Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 4, Problem 8EQ
As shown in Figure 4.17, coat color in rodents is governed by a gene interaction. An albino rat is crossed to a black rat. The ratio of their offspring is 1 agouti : 1 black : 2 albino. What are the genotypes of the parents?
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Pink eye and albinism are two recessive traits found in the deer mouse, Peromyscus maniculatus. In mice with pink eye, the eye is devoid of color and appears pink from the blood vessels within it. Albino mice are completely lacking color both in their fur and in their eyes. F. H. Clark crossed pink‑eyed mice with albino mice; the resulting F1 had normal coloration in their fur and eyes. He then crossed these F1 mice with mice that were pink‑eyed and albino and obtained the mice shown in the table below. It is very hard to distinguish between mice that are albino and mice that are both pink‑eyed and albino, so he combined these two phenotypic classes (F. H. Clark, 1936, Journal of Heredity 27:259−260).
Match the expected numbers of progeny with each phenotype if the genes for pink‑eye and albinism assort independently.
Phenotype
Observed
Expected
wild type, wild type
12
wild type, pink eyes
62
albino, wild type, or pink eyes
78
Total
152
152
Answer…
Coat color in mice is influenced by two genes, one for color (A) and one for the amount of pigment production (C). Mice with the wild type agouti coat color have a yellowish to brownish color. Mice also have a gene that determines the amount of pigment the hair produces.
Multiple crosses were made between male and female mice that were each heterozygous for both traits (AaCc). The data table shows the number of mice of each coat type. Calculate the average F1 generation coat color to answer the question.
Which of the following is the most probable interaction between the two genetic loci, A and C, based on the average F1 ratio results?
A - The two loci show an epistatic pattern with the loci C epistatic to loci A.B - The two loci show a codominant pattern with both loci affecting coat color.C - The two loci interact in a Mendelian pattern with A being completely dominant over C.D - The two loci show an incomplete dominance pattern with neither loci A nor C being dominant.
Pink-eye and albino are two recessive traits found in the deer mouse Peromyscus maniculatus. In pink-eyed mice, the eye is devoid of color and appears pink because of the blood vessels within it. Albino mice are completely lacking color, both in their fur and in their eyes. F. H. Clark crossed pink-eyed mice with albino mice; the resulting F1 had normal coloration in their fur and eyes. He then crossed these F1 mice with mice that were pink eyed and albino and obtained the following progeny. It is hard to distinguish between mice that are albino and mice that are both pink eyed and albino, so he combined these two phenotypes (F. H. Clark. 1936. Journal of Heredity 27:259–260). a. Give the expected numbers of progeny with each phenotype if the genes for pink-eye and albino assort independently. b. Use a chi-square test to determine if the observed numbers of progeny fit the number expected with independent assortment.
Chapter 4 Solutions
Genetics: Analysis and Principles
Ch. 4.1 - 1. Which of the following statements is true?
a....Ch. 4.2 - 1. Which of the following is not an example of a...Ch. 4.2 - Prob. 2COMQCh. 4.2 - 3. Polydactyly is a condition in which a person...Ch. 4.3 - The outcome of an individuals traits is controlled...Ch. 4.4 - Prob. 1COMQCh. 4.4 - Prob. 2COMQCh. 4.5 - Prob. 1COMQCh. 4.5 - Hemophilia is a blood-clotting disorder in humans...Ch. 4.6 - Prob. 1COMQ
Ch. 4.7 - 1. The Manx phenotype in cats is caused by a...Ch. 4.8 - Which of the following is a possible explanation...Ch. 4.9 - 1. Two different strains of sweet peas are...Ch. 4.9 - If the F1 offspring from question 1 are allowed to...Ch. 4 - 1. Describe the differences among dominance,...Ch. 4 - Discuss the differences among sex-influenced,...Ch. 4 - 3. What is meant by a gene interaction? How can a...Ch. 4 - Lets suppose a recessive allele encodes a...Ch. 4 - 5. A nectarine is a peach without the fuzz. The...Ch. 4 - 6. An allele in Drosophila produces a star-eye...Ch. 4 - A seed dealer wants to sell four-oclock seeds that...Ch. 4 - 8. The blood serum from one individual (let’s call...Ch. 4 - 9. Which blood type phenotypes (A, B, AB, and/or...Ch. 4 - A woman with type B blood has a child with type O...Ch. 4 - A type A woman is the daughter of a type O father...Ch. 4 - In Shorthorn cattle, coat color is controlled by a...Ch. 4 - In chickens, the Leghorn variety has white...Ch. 4 - Propose the most likely mode of inheritance...Ch. 4 - 15. A human disease known as vitamin D-resistant...Ch. 4 - 16. Hemophilia is an X-linked recessive trait in...Ch. 4 - 17. Incontinentia pigmenti, a rare, X-linked...Ch. 4 - 18. Scurs in cattle is a sex-influenced trait. A...Ch. 4 - In rabbits, the color of body fat is controlled by...Ch. 4 - Prob. 20CONQCh. 4 - 21. The trait of feathering in fowls is a...Ch. 4 - Based on the pedigree shown here for a trait...Ch. 4 - 23. The pedigree shown here involves a trait...Ch. 4 - Lets suppose you have pedigree data from thousands...Ch. 4 - Prob. 25CONQCh. 4 - 26. In humans, a very rare dominant allele that...Ch. 4 - 27. A sex-influenced trait in humans affects the...Ch. 4 - Three coat-color patterns that occur in some...Ch. 4 - Prob. 1EQCh. 4 - 2. In chickens, some varieties have feathered...Ch. 4 - 3. In sheep, the formation of horns is a...Ch. 4 - Prob. 4EQCh. 4 - In the clover butterfly, males are always yellow,...Ch. 4 - The Mic2 gene in humans is present on both the X...Ch. 4 - 7. Duroc Jersey pigs are typically red, but a...Ch. 4 - 8. As shown in Figure 4.17, coat color in rodents...Ch. 4 - 9. Summer squash exist in long, spherical, or disk...Ch. 4 - In a species of plant, two genes control flower...Ch. 4 - 11. Red eyes is the wild-type phenotype in...Ch. 4 - 12. As mentioned in Experimental Question E11, red...Ch. 4 - Lets suppose you were looking through a vial of...Ch. 4 - 14. When examining a human pedigree, what features...Ch. 4 - Lets suppose a gene exists as a functional...Ch. 4 - In oats, the color of the chaff is determined by a...
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- In rabbits, an allelic series helps determine coat color. The alleles, in order of dominance, are listed below. C=full coat color Cch-chinchilla Ch-himalayan c=white What is the predicted outcome for a CCh rabbit crossed with a Cchc rabbit? Draw out the cross and show the predicted genotypes and phenotypes for the offspring.arrow_forwardSpotting in horses is a dominant trait. Cross a homozygous spotted horse with a homozygous solid-colored horse. What are the genotypes and phenotypes of their offspring? Cross two of the offspring from the above cross. What are the genotypes and phenotypes or their offspring? Cross a heterozygous spotted horse with a solid-colored horse. What are the genotypes and phenotypes of their offspring?arrow_forwardIn mice, short hair is dominant over long hair. If a heterozygous shorthaired male is crossed with a heterozygous female, what are the genotypes of the parents?arrow_forward
- coat color in rodents is governed by agene interaction. An albino rat is crossed to a black rat. The ratioof their offspring is 1 agouti : 1 black : 2 albino. What are the genotypes of the parents?arrow_forwardIn Thomas Hunt Morgan's experiments examining the transmission of eye color in fruit-flies, he observed that when he crossed heterozyYgous red-eyed females to red-eyed males, 1/2 of the male offspring were white-eyed, while all of the female offspring are red-eved, Which of the following best explains the results? 1/2 of the male offspring inherit a white-eye color allele from their heterozygous mothers. Since there is no eye color gene on the Y chromosome, their eyes are white. 1/2 of the male offspring inherit a Y-chromosome from their fathers. Since there is no eye color gene on the Y chromosome, their eyes are white. All of the female offspring inherit a dominant, red-eyed allele from their mothers A 3 to 1 ratio of dominant to recessive offspring are expected in a single factor crossarrow_forwardIn cats, black fur color is caused by an X-linked allele; the other allele at this locus causes orange color. The heterozygote is tortoiseshell. What kinds of offspring would you expect from the cross ofan orange female and a black male? A) black females; orange malesB) tortoiseshell females; black malesC) tortoiseshell females; tortoiseshell males D) tortoiseshell females; orange males E) orange females; black malesarrow_forward
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