Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 4, Problem 4CONQ
Let’s suppose a recessive allele encodes a completely defective protein. If the functional allele is dominant, what does that tell you about the amount of the functional protein that is sufficient to cause the
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As seen in the photo, Labradors come in three colors-- black, brown and yellow. What is the genetic basis for these different coat colors? One gene produces melanin, a pigment which is deposited in the dog's fur and makes the color dark. With this gene, allele B (black) is dominant to allele b. Only in the case of a recessive homozygote (bb) will the dog's phenotype be brown. The regulatory gene is separate from the melanin gene but it acts as a switch, either turning the melanin gene on or turning it off. Allele E is dominant and allows for the melanin to be deposited in the dog's fur ("on" switch), but if the switch gene is a recessive homozygote, the melanin is blocked ("off" switch) and a yellow dog is the result!
1. Two other Labradors mate and produce puppies. Their genotypes are Bbee and BbEe. What color are each parent and what are the phenotypic rations of their offspring in the F1 Generation? Show your work with a Punnett square.
As seen in the photo, Labradors come in three colors-- black, brown and yellow. What is the genetic basis for these different coat colors? One gene produces melanin, a pigment which is deposited in the dog's fur and makes the color dark. With this gene, allele B (black) is dominant to allele b. Only in the case of a recessive homozygote (bb) will the dog's phenotype be brown. The regulatory gene is separate from the melanin gene but it acts as a switch, either turning the melanin gene on or turning it off. Allele E is dominant and allows for the melanin to be deposited in the dog's fur ("on" switch), but if the switch gene is a recessive homozygote, the melanin is blocked ("off" switch) and a yellow dog is the result!
Review the information on Labrador retrievers above. What are the phenotypic ratios of the F1 generation offspring of two dihybrids? Make sure to match the numbers with coat colors (e.g, which number in the ration goes with which color). Use a Punnett square to…
In humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A).
What is the genotype of someone who has cystic fibrosis?
What are the two different genotypes that a healthy person could have?
If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.
Chapter 4 Solutions
Genetics: Analysis and Principles
Ch. 4.1 - 1. Which of the following statements is true?
a....Ch. 4.2 - 1. Which of the following is not an example of a...Ch. 4.2 - Prob. 2COMQCh. 4.2 - 3. Polydactyly is a condition in which a person...Ch. 4.3 - The outcome of an individuals traits is controlled...Ch. 4.4 - Prob. 1COMQCh. 4.4 - Prob. 2COMQCh. 4.5 - Prob. 1COMQCh. 4.5 - Hemophilia is a blood-clotting disorder in humans...Ch. 4.6 - Prob. 1COMQ
Ch. 4.7 - 1. The Manx phenotype in cats is caused by a...Ch. 4.8 - Which of the following is a possible explanation...Ch. 4.9 - 1. Two different strains of sweet peas are...Ch. 4.9 - If the F1 offspring from question 1 are allowed to...Ch. 4 - 1. Describe the differences among dominance,...Ch. 4 - Discuss the differences among sex-influenced,...Ch. 4 - 3. What is meant by a gene interaction? How can a...Ch. 4 - Lets suppose a recessive allele encodes a...Ch. 4 - 5. A nectarine is a peach without the fuzz. The...Ch. 4 - 6. An allele in Drosophila produces a star-eye...Ch. 4 - A seed dealer wants to sell four-oclock seeds that...Ch. 4 - 8. The blood serum from one individual (let’s call...Ch. 4 - 9. Which blood type phenotypes (A, B, AB, and/or...Ch. 4 - A woman with type B blood has a child with type O...Ch. 4 - A type A woman is the daughter of a type O father...Ch. 4 - In Shorthorn cattle, coat color is controlled by a...Ch. 4 - In chickens, the Leghorn variety has white...Ch. 4 - Propose the most likely mode of inheritance...Ch. 4 - 15. A human disease known as vitamin D-resistant...Ch. 4 - 16. Hemophilia is an X-linked recessive trait in...Ch. 4 - 17. Incontinentia pigmenti, a rare, X-linked...Ch. 4 - 18. Scurs in cattle is a sex-influenced trait. A...Ch. 4 - In rabbits, the color of body fat is controlled by...Ch. 4 - Prob. 20CONQCh. 4 - 21. The trait of feathering in fowls is a...Ch. 4 - Based on the pedigree shown here for a trait...Ch. 4 - 23. The pedigree shown here involves a trait...Ch. 4 - Lets suppose you have pedigree data from thousands...Ch. 4 - Prob. 25CONQCh. 4 - 26. In humans, a very rare dominant allele that...Ch. 4 - 27. A sex-influenced trait in humans affects the...Ch. 4 - Three coat-color patterns that occur in some...Ch. 4 - Prob. 1EQCh. 4 - 2. In chickens, some varieties have feathered...Ch. 4 - 3. In sheep, the formation of horns is a...Ch. 4 - Prob. 4EQCh. 4 - In the clover butterfly, males are always yellow,...Ch. 4 - The Mic2 gene in humans is present on both the X...Ch. 4 - 7. Duroc Jersey pigs are typically red, but a...Ch. 4 - 8. As shown in Figure 4.17, coat color in rodents...Ch. 4 - 9. Summer squash exist in long, spherical, or disk...Ch. 4 - In a species of plant, two genes control flower...Ch. 4 - 11. Red eyes is the wild-type phenotype in...Ch. 4 - 12. As mentioned in Experimental Question E11, red...Ch. 4 - Lets suppose you were looking through a vial of...Ch. 4 - 14. When examining a human pedigree, what features...Ch. 4 - Lets suppose a gene exists as a functional...Ch. 4 - In oats, the color of the chaff is determined by a...
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- Let’s suppose a recessive allele encodes a completely defective protein. If the functional allele is dominant, what does that tell youabout the amount of the functional protein that is sufficient to causethe phenotype? What if the allele shows incomplete dominance?arrow_forwardRed-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___arrow_forwardLet’s suppose that two different X-linked genes exist in mice,designated with the letters N and L. Gene N exists in a dominant,normal allele and in a recessive allele, n, that is lethal. Similarly,gene L exists in a dominant, normal allele and in a recessive allele,l, that is lethal. Heterozygous females are normal, but males thatcarry either recessive allele are born dead. Explain whether or notit would be possible to map the distance between these two genesby making crosses and analyzing the number of living and deadoffspring. You may assume that you have strains of mice in whichfemales are heterozygous for one or both genes.arrow_forward
- A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a phenotypically normal couple, the man had a female 1 cousin (on his father’s side) who died from FH; the woman had a maternal uncle with FH. Using standard symbols, draw apedigree of these couple’s families. Write the genotypes of each family member.arrow_forwardIn fruit flies the allele for long wings (L) is dominant and the allele for short wings (l) is recessive. What is the likely genotype of a fruit fly with long wings?arrow_forwardA common kind of red-green blindness in humans is caused by the presence of a sex-linked recessive gene c, whose normal allele is c+. Using these genes, what are the possible genotypes and their corresponding phenotypes in males and females? Can two colorblind parents produce a normal son? (b) A normal daughter? (c) Can two normal parents produce a colorblind son? (d) a colorblind daughter?arrow_forward
- In man, muscular dystrophy is a condition in which the muscles waste away during early life and may result in a shorter life expectancy. It is due to a sex-linked, recessive gene. A certain couple has five children – three boys (ages 1yr, 3yrs, and 10yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of this disease. You are their family physician and they come to you for advice. What would you tell them about the chances of their other children developing the disease?arrow_forwardCystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f What is the genotype of individual #13? A) ff B) FF C) Ff D) it is impossible to tellarrow_forward(a) Which allele/s will MOST likely result in an anomalous phenotype? (b) Explain your answer in (a). (c) Which allele/s will LEAST likely result in an anomalous phenotype? (d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid structure.)arrow_forward
- Two brown bears have cubs in late spring. The mother bear has the phenotype for long front claws. The mother bear has the genotype (Aa), while the father has the same genotype as the mother. A) What percentage of the offspring will have long claws?arrow_forwardMendel's concept of dominance states that in a genotype where two different alleles of a locus are present, only the trait encoded by the dominant allele is observed. Give a molecular explanation for dominance, i.e. explain intracellular molecular events that can result in what we observe as dominance on a phenotypic level. Use the gene that encodes seed shape in peas as an example, where roun(R) is dominant over wrinkled(r), to explain how RR and Rr plants can have the same phenotype.arrow_forwardThis pedigree traces the inheritance of a trait in humans. Based on this pedigree, is the allele for this disease dominant or recessive? Is it sex-linked? Explain. What genotypes are most probable for the individuals labeled 4, 7, and 10?arrow_forward
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