What type of control generally involves binding of a repressor protein to a regulatoryDNA sequence?(one or two word answer only, please)

Repressor : DNA binding protein which inhibits the expression of 1 or more genes via the binding to…

Answered: What type of control generally involves…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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You plan to synthesize a peptide to be used as a vaccine to treat melanoma, a particularly aggressive form of skin cancer. Normally, gp100, a protein on the surface of melanocytes, activates cell growth when it is bound by its ligand. Activation of the growth pathway depends on the presence of threonine in the ligand. The effective peptide vaccine will mimic the natural ligand, but won’t cause cell growth and division. Below is the sequence of the natural ligand: LDMKTAG In order to ensure your newly designed peptide vaccine does not cause cell growth upon binding, you must substitute the Threonine residue at position 5. What amino acid would you replace it with, bearing in mind that the peptide should still be similar enough to bind to the gp100 protein in the surface of melanocytes. Explain your choice. Your vaccine will be administered as a topical cream, and you require your peptide to have an overall neutral charge in order to be functional. At what pH should you formulate…
Differential lengths of poly-A tails affect mRNA stability. Pre-transcriptional control Transcriptional control Translational control O Post-translational control
A transcription repressor results in a decrease in transcription of an operon. This is an example of ____________________________. a constitutive system an inducible system positive control negative control a repressible system
What is meant by the term attenuation? Is it an example of gene regulation at the level of transcription or translation? Explain your answer
Alternative exon splicing contributes to resolving the G-value paradox. Group of answer choices True False
A nonsense mutation results in an exon junction complex remaining on the mRNA. This mRNA: Question 7 options: Will be destroyed via nonsense mediated decay. Will be destroyed via RNA interference. Will not be translated due to RNA interference. Will be post-transcriptionally modified using RNA interference. Will be translated due to read-through strategy.
You have developed an activator of a non-receptor tyrosine kinase. In three different cell types that all contain this receptor your drug has different effects. In cell type A you see activation of gene X and gene Y; in cell type B you note activation of Gene X, but no change in the mRNA levels for Gene Y. In cell type C your drug has no effect on either Gene X or Y. Describe how could each choice (A-D) be a possibility to suit the scenario? a. Genes X & Y are controlled by two separate STATs (STAT X & STAT Y). Cell type A contains both STATs; cell type B contains STAT X only; cell type C has neither STAT. b. Genes X & Y are controlled by two separate STATs (STAT X & STAT Y) and two separate JAKs (JAK X & JAK Y). Cell type A contains both STATs and JAKs; cell type B contains both STATs but JAK X only; cell type C has both STATs but neither JAK. c. Genes X & Y are controlled by two separate STATs (STAT X & STAT Y), two separate JAKs (JAK X & JAK Y) and…
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Which of the following is not a general description of the gene expression regulation mechanisms that operate in eukaryotic organisms processing level control replication level control post translational leve control transcriptional level control translational level control
A string of 8 adenine nucleotides in the mRNA is required for function of an intrinsic transcription terminator in bacteria. True False
Some genes have the genetic code responsible for coding more than one protein based on the process of mRNA splicing in the nucleus of the eukaryotic cell. Select one: True False
Please answer asap and in short and content should not be palgarised please answer first question only

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What type of control generally involves binding of a repressor protein to a regulatory DNA sequence? (one or two word answer only, please)