Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16.5, Problem 1COMQ
Summary Introduction
Introduction:
Epigenetic cells are bound to have cells that cause cancer. There are many ways through which, the cells can cause cancer. Cancer cells are dangerous and cause an abnormality in gene expression and gene regulation. Epigenetic effects causes the cancer cells to pass to cells of the offspring.
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Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- Why do stem cells that have been damaged prefer apoptosis over repairing the genome? a. Stem cells cannot repair the damaged genome b. The repair machinery is not perfect and therefore prone to make mistakes c. They don't d. None of the abovearrow_forwardWhat are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequencearrow_forwardWhich of the following statements correctly describes a characteristic of tumor-suppressor gene? a) they are frequently overexpressed in cancerous cells. b) they are cancer-causing genes introduced into cells by viruses. c) they encode proteins that help prevent uncontrolled cell growth. d) they often encode proteins that stimulate the cell cycle.arrow_forward
- Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb? If so, how can this be?arrow_forwardWhich of the following best describes a gene that codes for a tumor-suppressor protein? a. One that helps to prevent progression through the cell cycle. b. One that helps prevent apoptosis. c. One that codes for a DNA repair enzyme. d. One that supports part of a growth factor signaling pathway.arrow_forwardInsulators may exert their effect by a. acting as a barrier to changes in chromatin structure. b. blocking the effects of neighboring enhancers. c. doing both a and b. d. none of the above.arrow_forward
- Which of the following types of mutations are advantageous to cancer cell growth? a. Those resulting in defective mismatch repair b. Inherited defects in double-strand DNA repair c. A defect in nucleotide-excision repair d. A, B, and C e. None of the abovearrow_forwardWhich of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin gene to be expressed at all times during the cell cycle B) a mutation that causes an oncogene to be turned off so that no protein is made C) a mutation that causes a Cdk gene to be turned off so that no protein is made D) a mutation that causes a tumor suppressor gene to be over-expressedarrow_forwardPost-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationarrow_forward
- Chromatin remodeling is affected by two processes, DNA methylation and a. base substitution b. histone covalent modifications c. ultraviolet radiation d. transcription factor bindingarrow_forwardSome cancers have been treated with drugs that demethylate DNA.Explain how these drugs might work. Do you think the cancer-causinggenes that responded to the demethylation are likely to have beenoncogenes or tumor-suppressor genes? Explain your reasoning.arrow_forwardWhich of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerasesarrow_forward
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