What are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequence

What are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequence

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter9: Molecular Biology

Section: Chapter Questions

Problem 11RQ: Post-translational control refers to: a. regulation of gene expression after transcription b....

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Question

What are epigenetic modifications?
a. the addition of reversible changes to histone
proteins and DNA
b. the removal of nucleosomes from the DNA
c. the addition of more nucleosomes to the DNA
d. mutation of the DNA sequence

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Epigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive gene expression? A. Histone acetylation B. Histone Methylation C. De-methylated DNA D. Methylated DNA
What degree of differences would you expect to see in the DNA base sequences and epigenetic marks of monozygotic twins? a. Similar differences in DNA base sequence and epigenetic marks b. Greater differences in DNA base sequence than epigenetic marks c. Greater differences in epigenetic marks than DNA base sequence d. No differences in either DNA base sequence or epigenetic marks
Which of these is NOT true of nucleosomes? A. Some post-translational modifications to histone proteins serve as binding sites for transcription factors. B. The position of nucleosomes is fixed on the genome and can not be changed. C. The position and post-translational modifications of histones can be inherited through mitosis. D. The binding between DNA and histone proteins can be disrupted by post-translational modifications.
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Define the following terms: a. epigenetics b. CpG island c. epimutation d. DNA methylation e. histone acetylation
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In Eukaryotes, DNA is a long molecule inside a tiny nucleus. a. How can this long chain fit in such space? b. How does it affect gene expression?
Why might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1A
Which of the following may produce more than one functional protein from an mRNA transcript?a. chromatin condensation b. transcriptional regulation c. epigeneticsd. alternative mRNA processing
Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA molecules
What would happen if a lysine residue that was normally acetylated was mutated to an arginine? A. There would probably be no affect on transcription B. The nucleosome affected by this mutation would be more likely to be uncondensed C. Genes within or near the nucleosome affected by this mutation would be more likely to be repressed D. RNA Pol II would have an easier time accessing the DNA at or near the affected nucleosome E. B and C are both correct