Chromatin remodeling is affected by two processes, DNA methylation and a. base substitution b. histone covalent modifications c. ultraviolet radiation d. transcription factor binding
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Chromatin remodeling is affected by two processes, DNA methylation and
a. base substitution
b. histone covalent modifications
c. ultraviolet radiation
d. transcription factor binding
Step by step
Solved in 3 steps
- Transcription factors a. help the RNA polymerase bind DNA b. are involved in chromatin remodeling, uncoil the DNA c. modulate transcription from the distance d. add the 5’ CAP to the RNAFor each statement below indicate whether it is true or false: A. Strand discrimination during the process of DNA repair is based on DNA methylation B. The genetic code has 64 amino acid-specifying codons C. Mutations in germline cells are more consequential to subsequent generations than mutations in somatic cells.Loosening the chromatin structure occurs because of Select one: a. Lysine methylation b. Lysine acetylation c. Lysine phosphorylation d. Lysine sumoylation
- In eukaryotes, chromatin remodeling plays an important role is gene regulation. This is because a. repositioning of the nucleosomes makes DNA accessible to transcription regulatory proteins b. the nucleosomes contain important regulatory regions c. chromatin remodeling activates gene expression d. chromatin remodeling represses gene expressionWhich of the following may produce more than one functional protein from an mRNA transcript?a. chromatin condensation b. transcriptional regulation c. epigeneticsd. alternative mRNA processingWhich of the following will increase the rate of transcription? a. Activation of a transcriptional repressor b. Inhibition of a transcriptional activator c. Histone methylation leading to chromatin compaction d. Removal of RNA polymerase
- Which of the following is an example of chromatin modification that stimulates gene expression? Group of answer choices A. alternative exon splicing b. microRNA binding to mRNA c. DNA methylation D. histone acetylationWhich illustration below correctly depicts the effect of histone modification in chromatin remodeling? (Ac- acetyl group, -H3K9trimethylated)? Ac Ac AC AC AC A. m 2 Ac Ac Ac Ac B. C. Ac Ac H3K9trimethylated Ac Ac AcEukaryotes such as humans have linear chromosomes. In order to signal the end of DNA replication, there is a large repetitive sequence of DNA called a telomere. The telomere region of the DNA signals a process called a. detachment b. termination c. elongation d. transcription
- Which of the following complex compound is used in the treatment of cancer?A. Cis platin B. Transplatin C. Potassium ferrocyanide D. Sodium cobal nitriteHistones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backboneWhich of the following statements is NOT true about chromatin architecture? A. The histone tails on heterochromatin are deacetylated B. Heterochromatin is heavily methylated C. Euchromatin is more likely to contain genes that are expressed at that time D. Euchromatin is heavily methylated