Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16, Problem 17CONQ
Explain how the VIN3/PRC2 complex specifically binds to the FLC gene.
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Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- In the regulatory switch experiment, what do you predict is a likely outcome in mice with the bat-mouse construct? Select one 1.) change in the nucleotide sequence of the Prx1 transcribed region 2.) change in the amount of Prx1 mRNA produced 3.)change in the amino acid sequence of the PRX1 protein 4.)change in the nucleotide sequence of the Prx1 mRNA producedarrow_forwardDiscuss in general terms the principle of the regulation of theexpression of the trp gene with attenuation in bacteria.arrow_forwardExplain one experimental strategy for determining the functional role of the mouse HoxD-3 gene.arrow_forward
- The p53 protein was discovered through its association with SV40 T antigen and assumed initially to be an oncoprotein. a. What is the current consensus as the function of p53 and what evidence caused this change in view? b. How does the effect of mutation in the p53 gene differ from the effect of mutation in the RB gene what is the molecular basis for this difference ?arrow_forwardExplain karyopherin exportins? What is it? What is its function? Why is iş important for the nucleus?arrow_forwardWhat do TATA boxes, initiators, and CpG islands have in common? Which was the first of these to be identified? Why?arrow_forward
- What are the advantages of using the T7 polymerase to control expression?arrow_forwardHow does the activity of human p53 get regulated through the interaction of the transactivation domains with its corresponding macromolecules when the cell is under stress vs unstressed conditions? based on this articles Primary paper: Lee, C. W., Martinez-Yamout, M. A., Dyson, H. J., & Wright, P. E. (2010). Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein. Biochemistry, 49(46), 9964–9971. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982890/#SD1 https://www.rcsb.org/structure/2L14 PDB file for TAD domainarrow_forwardExplain Sex-specific splicing of the primary fru transcript.?arrow_forward
- Briefly explain the steps to induce the expression of gene of interest using IPTG.arrow_forwardEpstein-Barr virus is associated with Burkitt’s lymphoma. The rate of EBV and c-myc gene translocation seems related, as both are highest in Equatorial Africa, lowest in North America and intermediate in South America. Explain what is c-myc translocation and why it results in overexpression of c-myc. What is the role of EBV in causing c-myc gene overexpression?arrow_forwardAn important mechanism for generating diversity in immunoglobulin light chain V-region sequences is based on the fact that the RAG recombinase generates hairpin structures, rather than blunt ends, at the cleavage sites between the recombination signal sequences and the coding sequences. Explain how this mechanism generates diversity at the junctions.arrow_forward
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