Can we treat cancer by restoring tumor suppressor function such as mutated p53 or pRb?  If so, how can this be?

Q: How can a defect in p53 gene contribute to cancer development?

A: Cancer is an abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some…

Q: What is the link between epigenetics and cancer?

A: Epigenetics is considered as the study in which the gene shows its behavior according to the…

Q: The p53 gene was discovered in 1979, but it was not clear whether the gene functioned as an oncogene…

A: An oncogene is a type of gene that is responsible for causing the cells to divide uncontrollably and…

Q: Mutations in three broad classes of genes have been implicated in the onset of cancer. Can you…

A: A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic…

Q: What are Two kinds of cancer-producing mutations?

A: Cancer is defined as any one of a large number of diseases characterized by the development of…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: What plays an important role in preventing cancer ?

A: Cancer may be a giant cluster of diseases characterized by the uncontrolled growth and spread of…

Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…

A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…

Q: If cancer is fundamentally a genetic disease, how might an environmental factor such as smoking…

A: Tumor is a mass of tissues. It may be benign or malignant. The cellular growth that occurs when the…

Q: Explain the role of epigenetic alterations in cancer ?

A: Genes are the hereditary unit in an organism and are passed on from the parental generation to the…

Q: How can cancer arise from stem cells?

A: Stem cells are unique human cells and can grow into several cell types. This can vary between cells…

Q: solving Peto’s paradox the key to cancer prevention?

A: In 1977, British epidemiologist Richard Peto reasoned that the cells in large bodied and long-lived…

Q: Which mutations are more common in cancers,  growth promoters  or suppressors and why?

A: Cancer is a complex group of disease affecting a wide range of cell and tissues. It results from…

Q: What are some examples of genes involved in cancer?

A: Cancer is a clinical condition in which there occurs abnormal cell division leading to the formation…

Q: illustrate some of the molecular mechanisms leading from loss-of-function mutations in…

A: Tumor suppressing genes also known as Anti - oncogenes are the  regulatory genes which regulates…

Q: You decide to have your genome sequenced. The results come back and show that you have a…

A: Any abrupt change in the DNA causes mutation. This may or may not change the function of the cell.…

Q: How mutations, chromosomal changes epigenetics, and environmental agents play roles in the…

A: Cancer cells breaks the most basic rule of cell behavior by which multicellular organism are built…

Q: What genes are involved in cancer?

A: Genes Involved In Cancer --- Genes  and Their Characteristics -- Genes are made up of pieces of DNA…

Q: What is cancer? What defects are commonly found in cancer cells? Do all cancer cells have mutations…

A: Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells…

Q: How do normal cells protect themselves from accumulating mutations in genes that could lead to…

A: Studies reveal that the p53 protein instructs cells to under-go apoptosis when mutations in the DNA…

Q: How Mutations Cause Cancer Phenotypes?

A: The medical condition of cancer is generally characterized by the presence of a cluster of cells…

Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…

A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…

Q: Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?

A: Biotechnology is a wide range of studies where it uses its techniques with biological systems to…

Q: Are all pluripotent stem cells created equal, however?

A: Pluripotent cells are capable of repeated division to form most or all of the cell types but cannot…

Q: Hi, can you elaborate about these two concepts: 1) Can telomere inhibition be good cancer…

A: Cancer is a condition in which cells proliferate abnormally and infiltrate, erode, and kill healthy…

Q: Drivers are mutations that drive the cancer process; passengers are mutations that arise randomly in…

A: Cancer is the uncontrolled division or growth of the cells. The causes of cancer differ widely but…

Q: Which of the following statements about cancer is correct? A. Cancer stem cells can make tumors…

A: Cancer is a disease that occurs when the cells in the body start dividing abnormally. They go out of…

Q: how do tumor suppressor genes and proto-oncogenes causes cancer?

A: Tumor suppressor genes- These are the normal genes and they are responsible for regulating cell…

Q: What is the difference between a proto-oncogene and a tumor suppressor gene?  How can mutations in…

A: Proto-oncogenes are normally switched off. But when they get activated they cause tumors. On the…

Q: How tumor-suppressor mutations contribute to cancer?

A: Cancer - Cancer is a type of disease in which cells divide in an uncontrolled manner. The cells…