Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16.1, Problem 2COMQ
An epigenetic modification to a specific gene may initially be established by
a. a transcription factor.
b. a non-coding RNA.
c. both a and b.
d. none of the above.
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An epigenetic modification to a specific gene may initially beestablished bya. a transcription factor.b. a non-coding RNA.c. both a and b.d. none of the above.
Which of the following is NOT a description of an epigenetic modification?
A. regulatory patterns that persisis in the absence of the original signal
B. stable alterations in gene expression without changes to the underlying DNA sequence
C. the persistence of gene expression patterns through cell division
D. an intrinsic signal that triggers cell differentiation
The effects of transposons can includeA. disruption of gene expression.B. prevention of gene expression.C. occurrence of inversions.D. occurrence of deletions.E. all of the above
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- How would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forwardWhich of the following is true of CpG islands? a. They are methylated near promoters of actively transcribed genes. b. They are unmethylated near promoters of actively transcribed genes. c. Acetylation of CpG islands leads to repression of transcription. d. CpG islands code for RNA molecules that activate transcription.arrow_forwardEnhancers: a. are always located upstream of the TATA sequence b. are always within 200 bp of the TATA sequence c. are responsible for time and tissue specific transcription d. All the above are true.arrow_forward
- How does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choicearrow_forwardAlternative RNA splicing a. is a mechanism for increasing the rate of transcription. b. can allow the production of proteins of different sizes from a gene. C. can allow the production of similar proteins from different RNAS. d. increases the rate of transcription. e. is due to the presence or absence of particular snRNAs.arrow_forwardWhich of the following is the best description of a transcription factor? A. A protein that brings the correct nucleotides to RNA polymerase B. A protein that binds to specific DNA sequences C. A DNA sequence that binds to RNA polymerase D. A modification that is made to mRNA to help it be exported from the nucleus. .arrow_forward
- Differential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single genearrow_forwardIs each of the following statements true or false? A. An enhancer is a type of regulatory element. B. A core promoter is a type of regulatory element. C. Regulatory transcription factors bind to regulatory elements. D. An enhancer may cause the down regulation of transcription.arrow_forwardWhich of the following is not true regarding gene regulation that involves DNA bending? a. The precise distance between the regulatory sequence and the promoter is important. b. Effect can be to repress transcription c. Effect can be to activation transcription d. Regulated genes can be thousands of base pairs away from the regulatory sitesarrow_forward
- Methylation can alter the process of gene expression because: B. By causing DNA to coil more tightly. A. By derailing the cellular transcription machinery. C. By removing the gene from the genome altogether. D. ALL answers A, B and C are correct. E. Only answers A and B are correct, but not C.arrow_forwardRegulatory transcription factors can be modulated by a. the binding of small effector molecules. b. protein-protein interactions. c. covalent modifications. d. all of the above.arrow_forwardWhich of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA moleculesarrow_forward
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