Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 8.3, Problem 13CC
If you put ouabain, an inhibitor of the Na+-K+ pump, on a neuron and then stimulate the neuron repeatedly, what do you expect to happen to action potentials generated by that neuron?
- (a) They cease immediately.
- (b) There is no immediate effect, but they diminish with repeated stimulation and eventually disappear.
- (c) They get smaller immediately, then stabilize with smaller amplitude.
- (d) Ouabain has no effect on action potentials.
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Following a current injection in a neuron, the membrane potential changes were recorded.
a) Is the produced voltage change a hyperpolarization or a depolarization, and why?
b) Is the produced voltage change excitatory or inhibitory, and why?
c) What is the reason the voltage change switches from passive to active?
Nerve membrane hyperpolarization after an action potential
a)Is the movement of membrane potential voltage below normal resting potential voltage. b) This Is mostly due to the slow-closing of K+ channels. c)Makes it more difficult to evoke another action potential. d) This Is mostly due to the slow-closing of Na+ channels.
Which of the following factors are important in the establishment of the membrane potential at -70 mV?
(i) Coulomb force;
(ii) Ion concentration;
(iii) Length of the axon;
(iv) Number of dendrites;
(v) Permeability of the cell membrane.
Select one:
a. (i), (iv), (v).
b. (ii), (iii).
c. (i), (ii), (v).
d. (iii), (iv).
Chapter 8 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 8.1 - Organize the following terms describing functional...Ch. 8.2 - Where do neurohormone-secreting neurons terminate?Ch. 8.2 - What is the difference between a nerve and a...Ch. 8.2 - Draw a chain of three neurons that synapse on one...Ch. 8.2 - What is the primary function of each of the...Ch. 8.2 - Name the two glial cell types that form myelin....Ch. 8.3 - Given the values in Table 8.2, use the Nernst...Ch. 8.3 - Would a cell with a resting membrane potential of...Ch. 8.3 - Would the cell membrane depolarize or...Ch. 8.3 - Match each ions movement with the type of graded...
Ch. 8.3 - Prob. 11CCCh. 8.3 - What is the difference between conductance and...Ch. 8.3 - If you put ouabain, an inhibitor of the Na+-K+...Ch. 8.3 - The pyrethrin insecticides, derived from...Ch. 8.3 - When Na+ channel gates are resetting, is the...Ch. 8.3 - A stimulating electrode placed halfway down an...Ch. 8.3 - Place the following neurons in order of their...Ch. 8.4 - Prob. 18CCCh. 8.4 - Prob. 19CCCh. 8.4 - Prob. 20CCCh. 8.4 - Prob. 21CCCh. 8.4 - Prob. 22CCCh. 8.4 - Classify the H+-neurotransmitter exchange as...Ch. 8.4 - Prob. 24CCCh. 8.4 - Prob. 25CCCh. 8.4 - Is Na+-dependent neurotransmitter reuptake...Ch. 8.5 - In Figure 8.24e, assume the postsynaptic neuron...Ch. 8.5 - In the graphs of Figure 8.24a, b, why doesnt the...Ch. 8.5 - Prob. 29CCCh. 8.5 - Prob. 30CCCh. 8 - List the three functional classes of neurons, and...Ch. 8 - Somatic motor neurons control __________, and...Ch. 8 - Prob. 3RQCh. 8 - Prob. 4RQCh. 8 - Prob. 5RQCh. 8 - Prob. 6RQCh. 8 - Axonal transport refers to the (a) release of...Ch. 8 - Match the numbers of the appropriate...Ch. 8 - Arrange the following events in the proper...Ch. 8 - List the four major types of ion channels found in...Ch. 8 - Prob. 11RQCh. 8 - An action potential is (circle all correct...Ch. 8 - Choose from the following ions to fill in the...Ch. 8 - What is the myelin sheath?Ch. 8 - List two factors that enhance conduction speed.Ch. 8 - Prob. 16RQCh. 8 - Draw and label a graph of an action potential....Ch. 8 - Prob. 18RQCh. 8 - Prob. 19RQCh. 8 - Create a map showing the organization of the...Ch. 8 - Prob. 21RQCh. 8 - Prob. 22RQCh. 8 - Prob. 23RQCh. 8 - Prob. 24RQCh. 8 - The presence of myelin allows an axon to (choose...Ch. 8 - Define, compare, and contrast the following...Ch. 8 - Prob. 27RQCh. 8 - Prob. 28RQCh. 8 - Prob. 29RQCh. 8 - Prob. 30RQCh. 8 - An unmyelinated axon has a much greater...Ch. 8 - The GHK equation is sometimes abbreviated to...Ch. 8 - In each of the following scenarios, will an action...
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- (b) Use Figure Q1(b) of an action potential to answer questions (i) until (iv) below. Choose the correct letter to represent each condition. (i) The neuron cannot fire an action potential because it is in a refractory period. (ii) The membrane potential is about -70 mV. (iii) The voltage-gated Na+ channels activation gates are closed, but the inactivation gates are open. (iv) Both gates of the voltage-gated Na+ channels are open. C Threshold B A E Figure Q1 (b)arrow_forwardWhat happens when a resting neuron’s membranedepolarizes?(A) There is a net diffusion of Na+out of the cell.(B) The equilibrium potential for K+(EK) becomesmore positive.(C) The neuron’s membrane voltage becomesmore positive.(D) The cell’s inside is more negative than the outsidearrow_forwardWhy are action potentials usually conducted in one direction?(A) Ions can flow along the axon in only one direction.(B) The brief refractory period prevents reopening of voltagegated Na+channels.(C) The axon hillock has a higher membrane potential thanthe terminals of the axon.(D) Voltage-gated channels for both Na+and K+open in onlyone direction.arrow_forward
- The extracellular sodium [Na+]0 is reduced in the saline bath. Following another current injection in a neuron, the membrane potential changes were recorded. a) Why has the membrane potential changed following the Na+ reduction? b) Why has the current injection produced no action potentials? c) How might you experimentally rescue action potential generation?arrow_forwardIn SA nodal cells the upstroke of the action potential:A)is characterized by a substantial overshoot component.B)results from rapid inward movement of Na+.C)results from inward movement of Ca2+D)results from inward movement of K+.arrow_forwardDuring the refractory period a) if a neuron reaches threshold the action potential goes to completion b) No stimulus of any strength will trigger a new action potential c) It is possible to trigger a new action potential but only with an unusually strong stimulus d) The signal grows weaker with distance e) The neuron fires at its maximum voltage if a stimulus depolarizes the neuron to thresholdarrow_forward
- If you increase the amount of neurotransmitter in the synaptic cleft, how would you expect the post-synaptic potential (PSP) to change? a) The PSP would be stronger b) The PSP would change from depolarizing to hyperpolarizing c) The PSP would not changearrow_forwardMatch each type of membrane potential (resting, threshold, graded, or action) to its definition: a) The membrane potential at which voltage gated sodium channels open. b) The membrane potential that triggers the action potential. c) Change in membrane potential that may or may not reach threshold and that may be depolarizing or hyperpolarizing. d) Rapid, strong depolarization followed by immediate repolarization. This potential is self-renewing if the right ion channels are nearby.arrow_forwardWhich of the following is true regarding the difference between graded and action potentials? a.) Action potential occur only when the surface of the neuron is myelinated, but graded potentials occur in both in both myelinated and non-myelinated neurons. b.) The magnitude of action potential depends on the magnitude of the stimulus, whereas graded potentials are all or none. c.) The magnitude of graded potential depends on the magnitude of the stimulus, whereas action potentials are all or none.arrow_forward
- 1. If you block calcium channels on an axon, which will not occur? A) exocytosis of neurotransmitter B) repolarization phase of the action potential C) depolarization phase of the action potential D) hyperpolarization phase of the action potential E) graded potentialarrow_forwardWhich of the following occurs first when voltage reaches the threshold level in a neuron plasma membrane? (a) voltageactivated Na1 channels open (b) K1 channels open (c) the membrane hyperpolarizes (d) neurotransmitter is released (e) K1 channels closearrow_forwardSuppose you inactivated a neuron’s Na/K exchange pumps (the active transporters), then immediately stimulated the neuron. i) Would the action potential fail to occur or be different from usual? Briefly explain. ii) Would repolarization fail to occur or be different from usual? Explain briefly. iii) Would the cell’s ability to respond to a second stimulus be changed? Explain briefly.arrow_forward
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