Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 8, Problem 17RQ
Draw and label a graph of an action potential. Below the graph, draw the positioning of the K+ and Na+ channel gates during each phase.
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Students have asked these similar questions
In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential.
Discuss the importance of threshold. How does this relate to the concept of APs being all or none?
Describe the action potential in terms of the different functional states of the voltage- gated Na+ membrane channels (Note: there are three states)
Draw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each)
A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential
a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to rest
Chapter 8 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 8.1 - Organize the following terms describing functional...Ch. 8.2 - Where do neurohormone-secreting neurons terminate?Ch. 8.2 - What is the difference between a nerve and a...Ch. 8.2 - Draw a chain of three neurons that synapse on one...Ch. 8.2 - What is the primary function of each of the...Ch. 8.2 - Name the two glial cell types that form myelin....Ch. 8.3 - Given the values in Table 8.2, use the Nernst...Ch. 8.3 - Would a cell with a resting membrane potential of...Ch. 8.3 - Would the cell membrane depolarize or...Ch. 8.3 - Match each ions movement with the type of graded...
Ch. 8.3 - Prob. 11CCCh. 8.3 - What is the difference between conductance and...Ch. 8.3 - If you put ouabain, an inhibitor of the Na+-K+...Ch. 8.3 - The pyrethrin insecticides, derived from...Ch. 8.3 - When Na+ channel gates are resetting, is the...Ch. 8.3 - A stimulating electrode placed halfway down an...Ch. 8.3 - Place the following neurons in order of their...Ch. 8.4 - Prob. 18CCCh. 8.4 - Prob. 19CCCh. 8.4 - Prob. 20CCCh. 8.4 - Prob. 21CCCh. 8.4 - Prob. 22CCCh. 8.4 - Classify the H+-neurotransmitter exchange as...Ch. 8.4 - Prob. 24CCCh. 8.4 - Prob. 25CCCh. 8.4 - Is Na+-dependent neurotransmitter reuptake...Ch. 8.5 - In Figure 8.24e, assume the postsynaptic neuron...Ch. 8.5 - In the graphs of Figure 8.24a, b, why doesnt the...Ch. 8.5 - Prob. 29CCCh. 8.5 - Prob. 30CCCh. 8 - List the three functional classes of neurons, and...Ch. 8 - Somatic motor neurons control __________, and...Ch. 8 - Prob. 3RQCh. 8 - Prob. 4RQCh. 8 - Prob. 5RQCh. 8 - Prob. 6RQCh. 8 - Axonal transport refers to the (a) release of...Ch. 8 - Match the numbers of the appropriate...Ch. 8 - Arrange the following events in the proper...Ch. 8 - List the four major types of ion channels found in...Ch. 8 - Prob. 11RQCh. 8 - An action potential is (circle all correct...Ch. 8 - Choose from the following ions to fill in the...Ch. 8 - What is the myelin sheath?Ch. 8 - List two factors that enhance conduction speed.Ch. 8 - Prob. 16RQCh. 8 - Draw and label a graph of an action potential....Ch. 8 - Prob. 18RQCh. 8 - Prob. 19RQCh. 8 - Create a map showing the organization of the...Ch. 8 - Prob. 21RQCh. 8 - Prob. 22RQCh. 8 - Prob. 23RQCh. 8 - Prob. 24RQCh. 8 - The presence of myelin allows an axon to (choose...Ch. 8 - Define, compare, and contrast the following...Ch. 8 - Prob. 27RQCh. 8 - Prob. 28RQCh. 8 - Prob. 29RQCh. 8 - Prob. 30RQCh. 8 - An unmyelinated axon has a much greater...Ch. 8 - The GHK equation is sometimes abbreviated to...Ch. 8 - In each of the following scenarios, will an action...
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- Draw and label an action potential, indicating the ion movements responsible for the rising phase and the falling phase.arrow_forwardFigure 35.11 Potassium channel blockers, such as amiodarone and procainamide, which are used to treat abnormal electrical activity in the heart, called cardiac dysrhythmia, impede the movement of K+ through voltage-gated K+ channels. Which part of the action potential would you expect potassium channels to affect?arrow_forwardState whether the channels listed would be open or closed at the corresponding numbered phases of the action potential graph. Phase on Graph Sodium Voltage Gated channels Potassium Voltage Gated channels 1 2 3 4arrow_forward
- Graph an action potential, showing the change inelectrical potential on the y-axis and time on the x-axis.Indicate on the graph the phases when voltage-gated Na1 andK1 ion channels are opened and when they are closedarrow_forwardDraw the current that you would expect to flow during a voltage clamp experiment on a typical neuron. Voltages and time course are shown. Briefly explain why the currents are inward or outward. Be sure to provide scale bars. You should definitely label the Y axis so that the peak current value is obvious. Draw the Na+ current you would expect if there were physiological ionic gradients. Draw the K+ current you would expect if there are physiological ionic gradients. Draw the K+ current you would expect if the bath solution and the intracellular solution are both 125 mM.arrow_forwardA membrane potential (Vm) labeled axis on the graph In the graph draw the phases of the action potential Include the channels involved and when they open and close matching them to the Vm Indicate the periods in which the action potential can or cannot occurarrow_forward
- List the characteristics of a local potential versus an action potentials. Describe where each happens and what type of gates are involved and what is achievedarrow_forwardBased upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forwardAt the peak of the action potential, Vm is approximately -65 mV. Assuming normal intracellular and extracellular K+ concentrations (refer to the table), (1) calculate the driving force (in mV) that acts on K+ ions and (2) use the information obtained in part 1 to determine the direction in which K+ ions will flow (i.e., into the cell or out of cell)arrow_forward
- Summarize the steps in generating an action potential as a flowchart. You can make your flowchart on paper and take a picture of it, or make it electronically. Be sure you’ve included: the location in the neuron and components of the neuron involved, the types of cellular transport and ions involved, how action potentials can be stimulated and inhibited. you can get the information from this: https://youtu.be/HYLyhXRp298arrow_forwardGive a detailed, step-by-step description of the stages of an action potential, including a description of and explanation for the refractory periods and the rising and falling phases as well as return to rest. In your explanation, make sure to include 1) summation principles, 2) key membrane potentials (values), 3) location of voltage changes along the membrane, 4) states of the various voltage-gated channels. The more detail, the better. There are 5 main steps.arrow_forwardA True OUTSIDE CELL This cell is at rest. False INSIDE CELL C D T Earrow_forward
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