Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 8.4, Problem 26CC
Is Na+-dependent neurotransmitter reuptake facilitated diffusion, primary active transport, or secondary active transport? Explain your reasoning.
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if an object b has a plasma sodium concentration of 135mOsm/L and an intracellular concentration of 4mOsm/L. It also has a plasma concentration of potassium of 20mOsm/L and an intracellular concentration of 200mOsm/L. studies identify that the cells have a permeability to potassium that is 10 times greater than sodium. What is the resting membrane potential
There are differences in Na+, K+, and Cl- ion concentrations across the membrane. Knowing that ions like to flow down their respective concentration gradients explain how the movement of Cl- and K+ ions can result in membrane hyperpolarization.
What type of ion channel contributes to the restingmembrane potential? Describe the permeabilitycharacteristics of the plasma membrane.
Chapter 8 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 8.1 - Organize the following terms describing functional...Ch. 8.2 - Where do neurohormone-secreting neurons terminate?Ch. 8.2 - What is the difference between a nerve and a...Ch. 8.2 - Draw a chain of three neurons that synapse on one...Ch. 8.2 - What is the primary function of each of the...Ch. 8.2 - Name the two glial cell types that form myelin....Ch. 8.3 - Given the values in Table 8.2, use the Nernst...Ch. 8.3 - Would a cell with a resting membrane potential of...Ch. 8.3 - Would the cell membrane depolarize or...Ch. 8.3 - Match each ions movement with the type of graded...
Ch. 8.3 - Prob. 11CCCh. 8.3 - What is the difference between conductance and...Ch. 8.3 - If you put ouabain, an inhibitor of the Na+-K+...Ch. 8.3 - The pyrethrin insecticides, derived from...Ch. 8.3 - When Na+ channel gates are resetting, is the...Ch. 8.3 - A stimulating electrode placed halfway down an...Ch. 8.3 - Place the following neurons in order of their...Ch. 8.4 - Prob. 18CCCh. 8.4 - Prob. 19CCCh. 8.4 - Prob. 20CCCh. 8.4 - Prob. 21CCCh. 8.4 - Prob. 22CCCh. 8.4 - Classify the H+-neurotransmitter exchange as...Ch. 8.4 - Prob. 24CCCh. 8.4 - Prob. 25CCCh. 8.4 - Is Na+-dependent neurotransmitter reuptake...Ch. 8.5 - In Figure 8.24e, assume the postsynaptic neuron...Ch. 8.5 - In the graphs of Figure 8.24a, b, why doesnt the...Ch. 8.5 - Prob. 29CCCh. 8.5 - Prob. 30CCCh. 8 - List the three functional classes of neurons, and...Ch. 8 - Somatic motor neurons control __________, and...Ch. 8 - Prob. 3RQCh. 8 - Prob. 4RQCh. 8 - Prob. 5RQCh. 8 - Prob. 6RQCh. 8 - Axonal transport refers to the (a) release of...Ch. 8 - Match the numbers of the appropriate...Ch. 8 - Arrange the following events in the proper...Ch. 8 - List the four major types of ion channels found in...Ch. 8 - Prob. 11RQCh. 8 - An action potential is (circle all correct...Ch. 8 - Choose from the following ions to fill in the...Ch. 8 - What is the myelin sheath?Ch. 8 - List two factors that enhance conduction speed.Ch. 8 - Prob. 16RQCh. 8 - Draw and label a graph of an action potential....Ch. 8 - Prob. 18RQCh. 8 - Prob. 19RQCh. 8 - Create a map showing the organization of the...Ch. 8 - Prob. 21RQCh. 8 - Prob. 22RQCh. 8 - Prob. 23RQCh. 8 - Prob. 24RQCh. 8 - The presence of myelin allows an axon to (choose...Ch. 8 - Define, compare, and contrast the following...Ch. 8 - Prob. 27RQCh. 8 - Prob. 28RQCh. 8 - Prob. 29RQCh. 8 - Prob. 30RQCh. 8 - An unmyelinated axon has a much greater...Ch. 8 - The GHK equation is sometimes abbreviated to...Ch. 8 - In each of the following scenarios, will an action...
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- What happens across the membrane of an electricallyactive cell is a dynamic process that is hard to visualizewith static images or through text descriptions. View thisanimation (http://openstaxcollege.org/l/dynamic1) toreally understand the process. What is the differencebetween the driving force for Na+ and K+? And what issimilar about the movement of these two ions?arrow_forwardthe maximal rate of solute movement during diffusion is greater than during mediated transport true or false?arrow_forwardThe extracellular concentration of Cl-Cl¯ is 123 mM and the intracellular concentration is 4 mM. In which direction does Cl-CI¯| flow through an open channel when the membrane potential is in the -60 mV-60 mV to +30 mV+30 mV range?arrow_forward
- If a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude? Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM. Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM a) At rest it is only permeable to potassium b) At rest it has some permeability to more than one of these ions c) At rest it is only permeable to chloride d) Rest it is not permeable to sodiumarrow_forwardSodium (Na*) and Potassium (K+) are equally distributed across the neuronal membrane at resting membrane potential because of the: O Unassisted passive diffusion across the membrane O Nat/K+ Pump O Nongated Channels Voltage-gated Channels Chemically-gated Channelsarrow_forwardWhat happens across the membrane of an electrically active cell is a dynamic process that is hard to visualize with static images or through text descriptions. View this animation (http://openstaxcollege.org/l/dynamic1) to learn more about this process. What is the difference between the driving force for Na+ and K+? And what is similar about the movement of these two ions?arrow_forward
- Below find the structures for ibogaine and cocaine. Ibogaine and cocaine inhibit the dopamine active transporter (DAT). This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase. Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively. (a) Define secondary active transport. (b) Is ibogaine an effective treatment for cocaine based on DAT binding?arrow_forwardSimilarly, what will be the effect on membrane potential if Cl- ions move into a cell?arrow_forwardThe resting membrane potential is established by? The Na+/K+-ATPase pumping Na+ into the cell and K+ out of the cell The Na+/K+-ATPase pumping K+ into the cell and Na+ out of the cell A larger diffusion of K+ out of the cell compared to diffusion of Na+ into the cell A larger diffusion of K+ into the cell compared to diffusion of Na+ out of the cell a) and d) b) and c)arrow_forward
- Usually , rates of diffusion vary inversely with molecular weights; so smaller molecules diffuse faster than do larger ones. In cells, however, calcium ion diffuses more slowly than does cAMP. Propose a possible explanation.arrow_forwardIn which way are voltage-gated ion channels and active transporters similar? a they are required to move small permeable molecules across cell membranes b they are proteins which move molecules across cell membranes c they utilize facilitated diffusion d they directly require energy in the form of ATP to move molecules e they generate concentration gradientsarrow_forwardMembrane potential in cells is constantly fluctuating. These fluctuations are called graded potentials and we will learn more about them in future lectures. Look at the fluctuating graded potential in the graph as an example. If Cl- generally has a relatively low membrane permeability, how would increasing Cl- permeability affect this graph?arrow_forward
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