Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 8, Problem 13RQ
Choose from the following ions to fill in the blanks correctly: Na+, K+, Ca2+, Cl−
- (a) The resting cell membrane is more permeable to _____ than to _____. Although _____ contribute little to the resting membrane potential, they play a key role in generating electrical signals in excitable tissues.
- (b) The concentration of _____ is 12 times greater outside the cell than inside.
- (c) The concentration of _____ is 30 times greater inside the cell than outside.
- (d) An action potential occurs when _____ enter the cell.
- (e) The resting membrane potential is due to the high _____ permeability of the cell.
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Choose the correct answer:
A) When the voltage gated K+ channels open K+ moves down its concentration
gradient from the ECF to inside the cell.
O B) The value for resting membrane potential is closer to the EK+ (Equilibrium
potential for K+) than the ENa+
O C) When the membrane potential is at rest the membrane is more permeable to
Na+ than it is to K+
O D) Closing of the voltage-gated Na+ channels increases the permeability of the
membrane to Na+
If a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude?
Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM.
Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM
a) At rest it is only permeable to potassium
b) At rest it has some permeability to more than one of these ions
c) At rest it is only permeable to chloride
d) Rest it is not permeable to sodium
There are differences in Na+, K+, and Cl- ion concentrations across the membrane. Knowing that ions like to flow down their respective concentration gradients explain how the movement of Cl- and K+ ions can result in membrane hyperpolarization.
Chapter 8 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 8.1 - Organize the following terms describing functional...Ch. 8.2 - Where do neurohormone-secreting neurons terminate?Ch. 8.2 - What is the difference between a nerve and a...Ch. 8.2 - Draw a chain of three neurons that synapse on one...Ch. 8.2 - What is the primary function of each of the...Ch. 8.2 - Name the two glial cell types that form myelin....Ch. 8.3 - Given the values in Table 8.2, use the Nernst...Ch. 8.3 - Would a cell with a resting membrane potential of...Ch. 8.3 - Would the cell membrane depolarize or...Ch. 8.3 - Match each ions movement with the type of graded...
Ch. 8.3 - Prob. 11CCCh. 8.3 - What is the difference between conductance and...Ch. 8.3 - If you put ouabain, an inhibitor of the Na+-K+...Ch. 8.3 - The pyrethrin insecticides, derived from...Ch. 8.3 - When Na+ channel gates are resetting, is the...Ch. 8.3 - A stimulating electrode placed halfway down an...Ch. 8.3 - Place the following neurons in order of their...Ch. 8.4 - Prob. 18CCCh. 8.4 - Prob. 19CCCh. 8.4 - Prob. 20CCCh. 8.4 - Prob. 21CCCh. 8.4 - Prob. 22CCCh. 8.4 - Classify the H+-neurotransmitter exchange as...Ch. 8.4 - Prob. 24CCCh. 8.4 - Prob. 25CCCh. 8.4 - Is Na+-dependent neurotransmitter reuptake...Ch. 8.5 - In Figure 8.24e, assume the postsynaptic neuron...Ch. 8.5 - In the graphs of Figure 8.24a, b, why doesnt the...Ch. 8.5 - Prob. 29CCCh. 8.5 - Prob. 30CCCh. 8 - List the three functional classes of neurons, and...Ch. 8 - Somatic motor neurons control __________, and...Ch. 8 - Prob. 3RQCh. 8 - Prob. 4RQCh. 8 - Prob. 5RQCh. 8 - Prob. 6RQCh. 8 - Axonal transport refers to the (a) release of...Ch. 8 - Match the numbers of the appropriate...Ch. 8 - Arrange the following events in the proper...Ch. 8 - List the four major types of ion channels found in...Ch. 8 - Prob. 11RQCh. 8 - An action potential is (circle all correct...Ch. 8 - Choose from the following ions to fill in the...Ch. 8 - What is the myelin sheath?Ch. 8 - List two factors that enhance conduction speed.Ch. 8 - Prob. 16RQCh. 8 - Draw and label a graph of an action potential....Ch. 8 - Prob. 18RQCh. 8 - Prob. 19RQCh. 8 - Create a map showing the organization of the...Ch. 8 - Prob. 21RQCh. 8 - Prob. 22RQCh. 8 - Prob. 23RQCh. 8 - Prob. 24RQCh. 8 - The presence of myelin allows an axon to (choose...Ch. 8 - Define, compare, and contrast the following...Ch. 8 - Prob. 27RQCh. 8 - Prob. 28RQCh. 8 - Prob. 29RQCh. 8 - Prob. 30RQCh. 8 - An unmyelinated axon has a much greater...Ch. 8 - The GHK equation is sometimes abbreviated to...Ch. 8 - In each of the following scenarios, will an action...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Assume that a membrane permeable to Na+ but not to Cl- separates two solutions. The concentration of sodium chloride on side 1 is higher than on side 2. Which of the following ionic movements would occur? a. Na+ would move until its concentration gradient is dissipated (until the concentration of Na+ on side 2 is the same as the concentration of Na+ on side 1). b. Cl- would move down its concentration gradient from side 1 to side 2. c. A membrane potential, negative on side 1, would develop. d. A membrane potential, positive on side 1, would develop. e. None of the preceding is correct.arrow_forwardDescribe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.arrow_forwardConformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forward
- The resting membrane potential…A) Can be approximated using the Goldman-Hodgkin-Katz equation.B) Represents a difference in charges across the cell membrane, resulting mostly from the passive flow of Na+ions.C) Has no influence on the driving force that acts on different ions across the cell membrane.D) Is equally dependent on the concentration gradients of potassium and sodium across the cell membrane.E) Becomes hyperpolarized during an excitatory graded potential.arrow_forwardIf: membrane potential=-70mV, ENa=+60mV, and Ex=-90mV, consider which directions Na+ and K+ will leak across the membrane. If both ions are crossing the membrane, what is the most important factor in determining whether membrane potential will become more positive or more negative?arrow_forwardif an object b has a plasma sodium concentration of 135mOsm/L and an intracellular concentration of 4mOsm/L. It also has a plasma concentration of potassium of 20mOsm/L and an intracellular concentration of 200mOsm/L. studies identify that the cells have a permeability to potassium that is 10 times greater than sodium. What is the resting membrane potentialarrow_forward
- The resting membrane potential…A) Can be approximated using the Nernst equation.B) Is established by a difference in charges across the cell membrane, with the inside more positive than the outside.C) Has no influence on the driving force for flow of a particular ion across the cell membrane.D) Is more dependent on the passive flow of potassium vs. sodium ions through leak channels across the cell membrane.E) Stays the same during an action potential.arrow_forwardJose measures membrane potential in two neighboring cells. He notices that when the membrane potential changes in one cell, the membrane potential of the neighboring cell changes in a similar manner. For example, if one cell hyperpolarizes, the neighboring cell also hyperpolarizes. He concludes the cells are electrically coupled. Which of the following is the most likely to cause the electrical coupling? a.) The electrical coupling is most probably due to integrins that connect the two cells. b.) The electrical coupling is most probably due to tight junctions that connect the two cells. c.) The electrical coupling is most probably due to desmosomes that connect the two cells. d.) The electrical coupling is most probably due to gap junctions that connect the two cells.arrow_forward1.A poison causes a drastic rise inE value with stimulation of the membrane.Thereafter membrane is slow to return towards resting membrane potential and levels off several millivolts above the threshold potential. This poison has likely affect which feature of the membrane? a) voltage gated na+ channels. b) voltage gated K+ channels. c) Na+/K+ Atp pump 2. All cell membrane demonstrate action potential if stimulated enough? True/False. 3. how many peaks are there in a compound action potential? a)2. b)4 c)6 d)8 4. Increasing the ionic concentration in the salt bridge results in E value increase to a point after which it plateeus. This is evidence brownian movement at work in the ionic solution that is keeping from energy flowing through the bridge with the fidelity that is seen in the metal bridge? True/ False 5. All cell membrane demonstrate action potential if stimulated enough? True or False.arrow_forward
- If sodium permeability were to increase compared to normal what would be the resulting effect on the membrane potential 1.The charge on the inside of the cell becomes less negative compared to resting conditions and hyperpolarizes 2.The charge on the inside of the cell becomes more negative compared to resting conditions and hyperpolarizes 3.The charge on the inside of the cell becomes less negative compared to resting conditions and depolarizes 4.The charge on the inside of the cell becomes more negative compared to resting conditions and depolarizesarrow_forwardAssume that in a neuron, the plasma membrane permeability values for potassium (K+), sodium (Na+), and Cl− are the following: PK = 1, PNa = 12, and PCl = 0.5. Based on physiological concentrations of K+, Na+, and Cl− (refer to the table), determine the membrane potential in this neuron.arrow_forwardThe resting membrane potential is established by? The Na+/K+-ATPase pumping Na+ into the cell and K+ out of the cell The Na+/K+-ATPase pumping K+ into the cell and Na+ out of the cell A larger diffusion of K+ out of the cell compared to diffusion of Na+ into the cell A larger diffusion of K+ into the cell compared to diffusion of Na+ out of the cell a) and d) b) and c)arrow_forward
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