Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 6, Problem 3RQ
Summary Introduction
To review:
The Baltimore classification of viral genomes.
Introduction:
The presence of a wide variety of viruses necessitates their classification into specific groups. This is required to explain their ancestry as well as relatedness. Viruses can be differentiated on the basis of their genome composition, size, capsid symmetry, envelope, and host.
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Describe the mechanism of replication of the eukaryotic virus SV40.
Coronaviruses have a positive-sense single stranded RNA genome.
a.) What is the genome replication strategy of this category of viruses?
b.) How do you think this feature affects the stability of the viral genome? (hint use figure below)
Mutation rates in different types of viruses. Estimates obtained for viruses belonging to the major indicated groups are shown as a function of genome size. This reveals an effect of genetic material (RNA/DNA) and genome size on viral mutation rates.
Match each of the following replication classes of viruses with the one description that best
describes it.
This virus class is composed of
segmented and non-segmented
helical viruses that carry an
RdRp within the virion into the
cell. Example: Rabies virus
These viruses are non-
enveloped, icosahedral, have
segmented genomes, and carry
their own RNA-dependent RNA
polymerase. The viral genome
is copied following assembly.
Example: Reovirus
This is the only class of RNA
viruses whose genome is
replicated by cellular enzymes
and not an RNA-dependent
RNA polymerase.
Cellular DNA polymerases
replicate this virus's non-
integrated genome, although
transcription is not the initial
event that takes place in the
process. Example:
Parvoviruses
In this class of viruses,
transcription occurs before
genome replication because
viral proteins are involved in
replicating the genome.
Example: Adenovirus
This class of viruses forms
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polymerases.…
Chapter 6 Solutions
Microbiology: An Evolving Science (Fourth Edition)
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What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY