Concept explainers
Syn5 is a virus that infects photosynthetic bacteria belonging to the genus Synechococcus. The Syn5 virion is icosahedral (660 Å in diameter) with a short tail and an appendage called a horn. The horn is located on a vertex directly opposite the tail. Syn5 follows the typical five steps observed for most viruses when they multiply, and progeny viruses are released when the host lyses. The assembly of Syn5 virions involves several proteins, including capsid proteins, scaffolding proteins, a portal protein, a terminase, tail proteins, and horn proteins. To better understand the assembly of Syn5 virions, scientists used a type of microscopy called Zernike phase contrast electron cryotomography. This type of microscopy improves the contrast typically seen for conventional cryotomography. In their studies, the scientists observed several different developing virus particles in infected cells. The particles were: (1) 660 Å icosahedron containing DNA and having a tail; (2) 660 Å icosahedron lacking DNA, tail, and horn; (3) 590 Å spherical particle lacking DNA, tail, and horn; (4) 660 Å icosahedron containing DNA and having a tail and horn; (5) 660 Å icosahedron containing DNA but lacking tail and horn. Based on these observations the scientists suggested a pathway for assembly of Syn5 virions. What are the functions of the portal protein and terminase? Organize the particles into an assembly pathway and indicate what you think has happened at each step
Step by stepSolved in 4 steps
- How common is ABV in the USA? In the United States, over half of adults have been infected with ABV by age 40. Once ABV is in a person's body, it stays there for life and can reactivate. Match terms with descriptions based on the text above. You can use an answer more than once or not at all. "Over half of adults have been infected with ABV by age 40." ABV could belong to this group of viruses: A. Human Papilloma Viruses B. Incidence of ABV C. Herpesviruses D. Prevalence of ABV by age 40arrow_forwardOVID-19 can be transmitted from an infected human to a healthy human by viral particles present in respiratory droplets such as saliva. This route of infection is ____________. Biological vector transmission Mechanical vector transmission Vehicle transmission Carrier-typearrow_forwardIn what part of the host cell does a herpesvirus genome replicate? Where does the viral genome reside during a latent infection?arrow_forward
- An antimicrobial drug binds to the HIV reverse transcriptase enzyme, preventing it from working. Which of the following is true of this drug? It would inhibit early replication steps of some viruses, but not affect normal eukaryotic cell activity. It would directly interfere with translation of some viral proteins and some eukaryotic proteins. It would block assembly/maturation steps of some viruses, and interfere with translation in eukaryotic cells. It would interfere with release of newly formed viruses from a host cell, but not affect eukaryotic cells. It would interfere with protein synthesis in bacteria, but not affect eukaryotic ribosomes. It would interfere with mRNA transcription in bacteria and viruses, but not affect eukaryotic transcription.arrow_forwardSelect all the following events that occurs in both the lytic and lysogenic cycle of bacteriophage T4 infection. viral protein synthesis digestion of host DNA attachment entryarrow_forwardWhich of the following statements is true regarding the M13 virus coat protein? (Refer to the figure) 9 Positive R, K, H Negative D, E 5 10 15 20 25 30 35 40 45 50 The amino acids in the beginning of the chain should face the DNA. The amino acids towards the higher number end of the chain should face the DNA. The amino acids at the higher end of the chain can destabilize the DNA. The amino acids at the beginning of the chain can stabilize the DNA.arrow_forward
- List three ways in which a virus differs from its prokaryotic host. Number these 1. 2. and 3arrow_forwardWhich of the following components of a virus is NOT encoded by its own genome? O capsid of HIV O lipid bilayer of HIV envelope O spike glycoproteins of HIV envelope O anchoring structures of bacteriophagearrow_forwardDuring infection of a cell by Coronavirus, the N protein is: found on the outer surface of the virus particles synthesized on bound ribosomes on the rough ER synthesized in the cytosol on free ribosomes part of the RNA-dependent RNA polymerase required for binding of the virus particle to cellsarrow_forward
- Viruses are made up of the same biomolecules as cellular organisms (DNA, RNA, proteins, lipids, etc.), which are synthesized through enzymatic dehydration reactions from building blocks and disassembled by enzymatic hydrolysis. They infect cells and replicate themselves using resources from the host cells. Scientists discovered a previously unknown strain of virus in the tropical Pacific Ocean and it can infect higher-order eukaryotes. Initial analysis revealed that the virus is mainly composed of nucleic acids, proteins, and lipids. Chemical analysis after complete hydrolysis revealed the following building blocks (by weight): Chemical components Nucleosides Amino acids Lipids, phosphates, and carbohydrates Percentage by weight 20 30 50 Analysis of percentages of nucleosides yielded the following results (by molar ratio): Nucleosides A G T C U Percentage by mole 19 29 19 29 4 Which of the following events mostly involves hydrolysis reaction after the virus infects…arrow_forwardDiscuss the structures found in a typical virus.arrow_forwardSome viruses such as HPV are linked to mutations causing certain types of cancer. What part of a virus life cycle can add mutations to host DNA? What type of bacteriophage, as defined by life cycle, could do this?arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education