Microbiology: An Evolving Science (Fourth Edition)
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ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 6.2, Problem 2TQ
Summary Introduction
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The advantage of icosahedron instead of some other polyhedron for a viral capsid.
Introduction:
Acapsid is a protective coat of virus or virion (virus presentextracellularly) that protects its genome during transmission into the host. It is composed of proteins. The proteins are in the form of several oligomeric structural subunits called protomers. The virus could be symmetrical or asymmetrical or combined aspects of both.
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How many protein subunits would be present in a complex icosahedral virus particle with a
triangulation (T) number of 8?
Compare the structure of an icosahedral capsid with that of a helical capsid. How do pentamers and hexamers associate to form a complete icosahedron? Which virus would have a longer helical capsid: a virus with a 7,200 base pair DNA genome or one with an 11,000 base ssRNA genome?
what is the Justification between complex capsid and helical capsid?
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Microbiology: An Evolving Science (Fourth Edition)
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A viral protein has a 20 amino acid amino acid chain consisting of the following primary structure: A-G-L-F-A-F-P-P-W-G-G-V-C-M-G-L-G-A-M-C In what places could these amino acids be found? a) Inside the hydrophobic core of a protein b) In a membrane that encloses the virus c) On the outside of a protein d) In a virus nail on the surface of the virusarrow_forwardYou have recently isolated a virus associated with a human disease. The virus particles are spherical, ~100 nm in diameter, and possess an envelope. Would you expect to find glycoproteins in the viral envelope? yes Would knowing that the particles are spherical mean that they are built with icosahedral symmetry? [Select]arrow_forwardA particular animal virus requires the use of DNA polymerase from its host, since it does not possess its own DNA polymerase enzyme. Which of the following assumptions in A-D would likely be correct regarding this virus? A) O This virus could not be a retrovirus type. B) OIt could be a (-) ss RNA virus. C) O It could be a (+) ss RNA virus. D) O The vVirus life cycle very likely includes going to the host cell nucleus. E) O All ofA-D are correct assumptions.arrow_forward
- Why must viruses repeat the same capsid protein subunits over and over again, rather than having hundreds of different capsid proteins?arrow_forwardViruses are made up of the same biomolecules as cellular organisms (DNA, RNA, proteins, lipids, etc.). They infect cells and replicate themselves using resources from the host cells. Scientists discovered a previously unknown strain of virus in the tropical Pacific Ocean and it can infect higher-order eukaryotes. Initial analysis revealed that the virus is mainly composed of nucleic acids, proteins, and lipids. Chemical analysis after complete hydrolysis revealed the following building blocks (by weight): Chemical components Nucleosides Amino acids Lipids, phosphates, and carbohydrates Percentage by weight 20 30 50 Analysis of percentages of nucleosides yielded the following results (by molar ratio): Nucleosides A G T C U Percentage by mole 19 29 19 29 4 Researchers determined that the lipids found in the virus form a bilayer membrane surrounding the virus, and are obtained from the membrane of the host cell during virus maturation and exit from host cell. Further…arrow_forwardThe assembly of new viral capsomeres and nucleic acid molecules take place with the help of an assembler protein true or false?arrow_forward
- Define the following: (a) virion (b) capsid (c) nucleocapsid (d) protein spikearrow_forwardIf a viral host cell has a mutation that interferes with the addition of carbohydrates to proteins (glycoproteins) during processing in the Golgi apparatus, which of the following processes is most likely to occur? O A. Viruses released by that host cell would have a decreased ability to infect cells than the virus that originally infected the cell. B. The virus-encoded protease would be unable to cleave large viral proteins into smaller, functional polypeptides. OC. The virus would be unable to replicate within the host cell. D. Viruses released by that cell are novel and would result in infections with higher mortality rates.arrow_forwardC) complex D) polyhedral 23. The first step in viral infection is the recognition between the virus and the host cell. Which of the following statements best describes how that occurs? A) The viral genome matches the host cell genome. B) Surface proteins on the virus are recognized by receptor proteins found in the plasma membrane of the host cell. C) The viral genome is recognized by the capsid that surrounds the host cell genome. D) The envelope on the virus is recognized by the host cell genome.arrow_forward
- As a general rule, viruses are not considered to be alive based on several reasons. One such reason is that some viruses use RNA as their genetic material instead of DNA. Which of the five biological themes does this violate? Briefly explain why.arrow_forwardAssume you isolate a single stranded (+) RNA virus. When you examine the proteins in the virus, you find that it does NOT contain replicase enzymes within its capsid. Which of the following is true? This virus must have a gene that encodes replicase. This virus will not be able to enter a host cell. Its genome cannot be translated (the process of translation) by the host cell ribosomes. A DNA copy of the viral genome has to be made before viral genes are expressed. This virus must lack surface antigens.arrow_forward1. "One structural form used in building virus particles is based on the icosahedron. Describe, either in words or in a diagram, the organization (number of capsomers, etc.) of the simplest virus particle of this form. 2. If a virus has a negative‐sense RNA genome, what enzymatic activity (if any) will be found as part of the virion, and what will be the first step in expression of the viral genome?"arrow_forward
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What Is A Virus ? ; Author: Peekaboo Kidz;https://www.youtube.com/watch?v=YS7vsBgWszI;License: Standard YouTube License, CC-BY