Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 28.2, Problem 5TQ
Summary Introduction

To review:

The role of IgG antibody titers in the diagnosis of recently acquired diseases.

Introduction:

Immunoglobulin G (IgG) is a type of antibody. 75% (percent) of serum antibodies present in humans are represented by IgG. It is most commonly found in blood circulation. Plasma B (bone marrow) cells are responsible for the production and release of IgG. They have two antigen-binding sites.

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Innate lymphoid cells reside primarily in tissues such as the lungs, the lining of the gastrointestinal tract, and the skin, because these sites represent the major routes of entry of pathogens into the body. Several different subsets of innate lymphoid cells exist, and each is specialized to respond to a category of pathogen (e.g., viruses, extracellular bacteria, helminthic parasites, etc). a) True b) False
Let’s say there are two closely related viruses, let’s call them Guernsey virus and Micro virus. These two viruses only infect epithelial cells. Their surface antigens are sufficiently similar that there are a number of shared epitopes between the two viruses. Choose one of the following: A) If you get infected and successfully recover from one virus, it’s quite possible that you’ll have neutralizing antibodies against the other. B) If you get infected and successfully recover from one virus, you’ll still be susceptible to the other one because the antigens aren’t exactly the same. C) If you get infected and successfully recover from one virus, it’s likely that getting infected with the other virus will be worse because of the common phenomena of antibody-dependent enhancement. D) Not enough information has been given.
Which antibody type description among A- D is falsely characterized? A) O IgA: form dimers; prevent adherence of pathogens to mucosal surfaces 1f1 B) O IgG: circulating antibody with multiple functions; formed in high numbers in secondary antibody response C) O IgM: forms multimers whose function is agglutination of infectious microbes D) O IgE, IgD: carry out their function while bound to the surfaces of specific cell types E) O None are false, A-D are all correct
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Serology 101: Testing for IgG and IgM antibodies; Author: Beckman Coulter Dx;https://www.youtube.com/watch?v=LtqKB-qpJrs;License: Standard youtube license