Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Why does antibody titer rise after infection? Is a
high antibody titer indicative of an ongoing infection?
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- Infants and young children with deficiencies in specific complement components present with recurrent respiratory infections caused by extracellular bacteria. The peak age of susceptibility is between 6 and 12 months after birth. At this time, as shown in figure below, maternal antibodies acquired by the child during fetal gestation are nearly gone, but the child is not yet generating robust antibody responses to new infections, as indicated by the low circulating levels of IgG and IgA. As children with this immunodeficiency get older, they outgrow this disease and show no further evidence of these recurrent infections. Based on this information, name one likely gene deficiency (in the complement system) that could cause this primary immunodeficiency, and the specific complement pathway likely to be affected. Explain your answer.arrow_forwardGive the sequence of events from the time the B-cell encounters the antigen to actual antibody production.arrow_forwardExplain why IgM has a stronger power of agglutination than antibodies of any other class.arrow_forward
- How different are theactions of antibodies againstbacteria and against virus?Why is the cellular immuneresponse activated in case ofchronic viral infection?arrow_forwardHow can the anamnestic response be explained in immunologic terms?arrow_forward1) SDS PAGE gels can be probed with NBT/BCIP to perform an immunoblot true/ false 2) the direction of migration of protiens through a matrix is due to most proteins in natur having a net negative charge true/false 3) PBST is a buffer that is used for blocking the membrane during immunoblotting. true/false 4) the buffer used during for transferring proteins to nitrocellulose methanol. true/false 7) The size of the pores of a polyacrylamide gel dcreases as concentrations of polyacrylamide increases. True or false 10) The secondary antibody used in laboratory for western blotting is conjugated to which enzyme A) Alkaline decarboxylase B) GAPDH C) Alkaline Phosphatase D) Horseeradish peroxide 13) In protien electrophroresis, what reagent present in the sample buffer is used to eliminate difference in the charge densities of protein A) SDS B) 2- mercaptoethanol C) Tris-HCL pH6.8 D) Tris- HCL PH 8.8arrow_forward
- List FOUR features of the acute and chronic responses to infection and name TWO cytokines involved in the acute response. Thank you!arrow_forwardIn radial immunodiffusion what are the circular precipitating rings composed of, and what do they represent?arrow_forwardWhat are the functions of Helper T cell markers?arrow_forward
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