Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 22, Problem 62P
Interpretation Introduction
Interpretation:
The regulation of fatty acid
The reciprocal control of fatty acid synthesis and degradation must be determined.
Concept introduction:
The fatty acids are degraded in a sequential manner, that is two carbon units at the carboxyl end of the molecule are removed in each step. The process of beta-oxidation of fatty acids degrades the fatty acids. The process of fatty acid synthesis is a stepwise process, which occurs by the addition of two-carbon units. These carbon units are provided by the acetyl-CoA, derived from glucose oxidation.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Discuss the regulation of fatty acid metabolism by the isozymic forms of acetyl CoA carboxylase. Explain the reciprocal control of fatty acid synthesis and degradation and the various means by which this control is achieved
Discuss how the isozymic forms of acetyl CoA carboxylase regulate fatty acid metabolism. Explain the reciprocal regulation of fatty acid production and breakdown, as well as the numerous mechanisms that are used to accomplish this control.
Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of different methods. Make a list of everything that comes to mind.
Chapter 22 Solutions
Biochemistry
Ch. 22 - Prob. 1PCh. 22 - Prob. 2PCh. 22 - Prob. 3PCh. 22 - Prob. 4PCh. 22 - Prob. 5PCh. 22 - Prob. 6PCh. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Prob. 9PCh. 22 - Prob. 10P
Ch. 22 - Prob. 11PCh. 22 - Prob. 12PCh. 22 - Prob. 13PCh. 22 - Prob. 14PCh. 22 - Prob. 15PCh. 22 - Prob. 16PCh. 22 - Prob. 17PCh. 22 - Prob. 18PCh. 22 - Prob. 19PCh. 22 - Prob. 20PCh. 22 - Prob. 21PCh. 22 - Prob. 22PCh. 22 - Prob. 23PCh. 22 - Prob. 24PCh. 22 - Prob. 25PCh. 22 - Prob. 26PCh. 22 - Prob. 27PCh. 22 - Prob. 28PCh. 22 - Prob. 29PCh. 22 - Prob. 30PCh. 22 - Prob. 31PCh. 22 - Prob. 32PCh. 22 - Prob. 33PCh. 22 - Prob. 34PCh. 22 - Prob. 35PCh. 22 - Prob. 36PCh. 22 - Prob. 37PCh. 22 - Prob. 38PCh. 22 - Prob. 39PCh. 22 - Prob. 40PCh. 22 - Prob. 41PCh. 22 - Prob. 42PCh. 22 - Prob. 43PCh. 22 - Prob. 44PCh. 22 - Prob. 45PCh. 22 - Prob. 46PCh. 22 - Prob. 47PCh. 22 - Prob. 48PCh. 22 - Prob. 49PCh. 22 - Prob. 50PCh. 22 - Prob. 51PCh. 22 - Prob. 52PCh. 22 - Prob. 53PCh. 22 - Prob. 54PCh. 22 - Prob. 55PCh. 22 - Prob. 56PCh. 22 - Prob. 57PCh. 22 - Prob. 58PCh. 22 - Prob. 59PCh. 22 - Prob. 60PCh. 22 - Prob. 61PCh. 22 - Prob. 62P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Define beta-oxidation of fatty acids? Describe in detail three different steps of beta-oxidation of FAs.arrow_forwardIn fatty acid biosynthesis explain the following two parts -(a) What effect will an increase in oxaloacetate in mitochondria have on fatty acid biosynthesis?(b) How insulin and glucagon affect fatty acid oxidation and biosynthesis reactions/pathways, name them.arrow_forwardGlucagon secretion causes inhibition of intracellular acetyl-CoA carboxylase activity by several mechanisms. Name all you can think of.arrow_forward
- . Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.arrow_forwardA number of genetic deficiencies in acyl CoA dehydrogenases have been described. This deficiency presents early in life after a period of fasting. Symptoms include vomiting, lethargy, and sometimes coma. Not only are blood levels of glucose low ( hypoglycemia), but starvation-induced ketosis is absent. Provide a biochemical explanation for these last two observations.arrow_forwardDiscuss the metabolic rationale for phosphorylation of acetyl-CoA carboxylase by AMP-activated protein kinase (AMPK) and cyclic AMP–dependent protein kinase (PKA).arrow_forward
- explain how α-tocopherol and ascorbate work together in suppressing the oxidation of polyunsaturated fatty acidsarrow_forwardBriefly explain the malate-aspartate shuttle. Distinguish between this shuttle with the glycerol -phosphate shuttle based upon their transport of reducing equivalents and their potential for ATP synthesis.arrow_forwardphosphofructokinase reaction of Fructose-2,6-bisphosphate is a regulator of both glycolysis and gluconeogenesis for the glycolysis and the fructose-1,6-bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose-2,6-bisphosphate is regulated by many hormones, second messengers, and enzymes. Classify each condition according to its effect on glycolysis and gluconeogenesis Activates glycolysis and inhibits gluconeogenesis Activates gluconeogenesis and inhibits glycolysis Answer Bank activation of PFK-2 increased glucagon levels increased levels of cAMP increased levels of fructose-2,6-bisphosphate activation of fructose-2,6-bisphosphatase (FBPase-2)arrow_forward
- phosphofructokinase reaction of Fructose-2,6-bisphosphate is a regulator of both glycolysis and gluconeogenesis for the glycolysis and the fructose-1,6-bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose-2,6-bisphosphate is regulated by many hormones, second messengers, and enzymes. Classify each condition according to its effect on glycolysis and gluconeogenesis Activates glycolysis and inhibits gluconeogenesis activation of PFK-2 increased levels of cAMP Activates gluconeogenesis and inhibits glycolysis increased levels of fructose-2,6-bisphosphate activation of fructose-2,6-bisphosphatase (FBPase-2) increased glucagon levelsarrow_forwardThe total degradation of a fatty acid with an odd number of carbons yields acetyl-CoA and another compound, X. Show the structure of X, and describe the pathway by which it is converted into a citric acid cycle intermediate, including where any cofactors participate.arrow_forwardIdentify different types of organic reaction mechanism (SN1, SN2, etc.) and reaction types (Addition, elimination, etc ) in the following metabolic pathways. 1. Catabolism of triacylglycerols- beta-oxidation pathway 2. Biosynthesis of fatty acids from Acetyl CoA 3. Glycolysis (from glucose to two molecules of pyruvate) 4. Conversion of Pyruvate to Acetyl CoA 5. Citric acid cycle 6. Gluconeogenesis pathway (pyruvate to glucose)arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY