Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Chapter 22, Problem 28P
Interpretation Introduction
Interpretation:
To determine whether the given statements are true or false.
Concept introduction:
The process of fatty acid synthesis occurs in the cytosol of the animal cells, while it occurs in the stroma of chloroplast in the plant cells. It is a stepwise process, which occurs by the addition of two-carbon units. These carbon units are provided by the acetyl-CoA, derived from glucose oxidation.
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Compare between the Kreb cycle and fatty acid
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1. The type of metabolic pathway (catabolic or
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2. The reducing or oxidizing coenzymes needed
for these pathways
3. Location of these pathways inside the cell.
4. Fate of acetyl CoA in both pathways
Ammonia isa. a by-product of lipid metabolism.b. formed during ketogenesis.c. converted into urea in the liver.d. produced during lipogenesis.e. converted to keto acids.
Fatty acids are oxidized by acyl COA dehydrogenase. Branched fatty acids, containing a methyl group at beta carbons cannot be oxidized by this enzyme. How does the oxidation of such branched fatty acids take place? Explain with all set of reactions and enzymes involved.. give necessary detail.. avoid cpy righting
Chapter 22 Solutions
Biochemistry
Ch. 22 - Prob. 1PCh. 22 - Prob. 2PCh. 22 - Prob. 3PCh. 22 - Prob. 4PCh. 22 - Prob. 5PCh. 22 - Prob. 6PCh. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Prob. 9PCh. 22 - Prob. 10P
Ch. 22 - Prob. 11PCh. 22 - Prob. 12PCh. 22 - Prob. 13PCh. 22 - Prob. 14PCh. 22 - Prob. 15PCh. 22 - Prob. 16PCh. 22 - Prob. 17PCh. 22 - Prob. 18PCh. 22 - Prob. 19PCh. 22 - Prob. 20PCh. 22 - Prob. 21PCh. 22 - Prob. 22PCh. 22 - Prob. 23PCh. 22 - Prob. 24PCh. 22 - Prob. 25PCh. 22 - Prob. 26PCh. 22 - Prob. 27PCh. 22 - Prob. 28PCh. 22 - Prob. 29PCh. 22 - Prob. 30PCh. 22 - Prob. 31PCh. 22 - Prob. 32PCh. 22 - Prob. 33PCh. 22 - Prob. 34PCh. 22 - Prob. 35PCh. 22 - Prob. 36PCh. 22 - Prob. 37PCh. 22 - Prob. 38PCh. 22 - Prob. 39PCh. 22 - Prob. 40PCh. 22 - Prob. 41PCh. 22 - Prob. 42PCh. 22 - Prob. 43PCh. 22 - Prob. 44PCh. 22 - Prob. 45PCh. 22 - Prob. 46PCh. 22 - Prob. 47PCh. 22 - Prob. 48PCh. 22 - Prob. 49PCh. 22 - Prob. 50PCh. 22 - Prob. 51PCh. 22 - Prob. 52PCh. 22 - Prob. 53PCh. 22 - Prob. 54PCh. 22 - Prob. 55PCh. 22 - Prob. 56PCh. 22 - Prob. 57PCh. 22 - Prob. 58PCh. 22 - Prob. 59PCh. 22 - Prob. 60PCh. 22 - Prob. 61PCh. 22 - Prob. 62P
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- Lipids area. stored primarily as triglycerides.b. synthesized by beta-oxidation.c. broken down by oxidative deamination.d. All of these are correct.arrow_forwardDifferentiate fatty acid synthesis and degradation in terms of the following: Fatty acid synthesis Fatty acid degradation a. Subcellular location b. End product c. Co-factors d. Carriers of acyl/acetyl groups between the mitochondria and the cytosolarrow_forwardfill in the blanks The 2C units of acetyl CoA necessary for fatty acid synthesis in the cytosol comes from the 6C compound ( ). The cleavage of this 6C molecule into a 4C and 2C molecule is by the enzyme ( ). Recycling of the 4C molecule back into the mitochondria generates the ( ) molecule nessary for fatty acid synthesis.arrow_forward
- The effect of pH on enzyme activity. 2. The effect of pH on enzyme activity. pH 1.0 Reaction rate 8.5 1.5 10.0 2.0 8.5 2.5 3.0 7.0 5.5 3.5 3.0 a. “DRAW A LINE GRAPH OF THE RESULTS OF THE EFFECTS OF pH ON THE ENZYME PEPSIN'S REACTION RATE." b.WHY DO YOU THINK IT WORKS BEST AT SUCH AN ACIDIC pH? 5O50 5arrow_forwardFatty acids are oxidized by acyl COA dehydrogenase. Branched fatty acids, containing a methyl group at beta carbons cannot be oxidized by this enzyme. How does the oxidation of such branched fatty acids take place? Explain with all set of reactions and enzymes involved. . give necessary details as well.. do not copyrightarrow_forwardStatements:(1) Bile acids are cholesterol oxidation products.(2) Glycerophospholipids differ structurally from fats in the number of ester linkages present.(3) Stearic acid and linolenic acids are the two essential fatty acids. a. All three statements are true. b. Two of the three statements are true. c. Only one of the statements is true. d. None of the statements is true.arrow_forward
- Chemistry - Pyruvate can NOT be used to synthesize:A. Fatty acids B. AcetoneC. None of the aforementionedD. Amino AcidsE. Ethanol or lactate - A muscle cell is working extremely hard in conditions of low glucose levels and an anaerobic environment. One way to obtain its energy in that state would be:A. by means of glycogenolysisB. stimulating gluconeogenesis in the liverC. All of the aboveD. by means of lactate dehydrogenase - We should consider the Krebs Cycle important in:A. AnabolismB. NoneC. CatabolismD. Botharrow_forwardAdipose tissue cannot resynthesize triacylglycerols from glycerol released during lipolysis (fat breakdown). Why not? Describe the metabolic route that is used to generate a glycerol compound for tri- acylglycerol synthesis.arrow_forwardWhich of the following statements is true of the β - oxidation of an unsaturated fatty acid? a. It is identical to the β-oxidation of a saturated fatty acid. b. It involves an extra step to convert a cis double bond to a trans double bond. c. It involves an extra step to convert a trans double bond to a cis double bond. d. It is completely different from the β-oxidation of a saturated fatty acid.arrow_forward
- Consider docosanoic acid C12H43CO2H a. Label the alpha and beta Carbons. Show the beta-oxidation in an EXPANDED structure. b. Draw each acyl CoA derived from this fatty acid. c. How many acetyl Co A molecules are formed by complete beta-oxidation? d. How many cycles of beta-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid? Show the complete computation. f. How many moles of ATP per gram of fatty acid is formed from the complete catabolism of the given fatty acid? g. What is the molar mass of the given fatty acid? Solution: Show here the complete computations, [from a to e]arrow_forwardAdipose tissue cannot resynthesize triacylglycerols from glycerol released during lipolysis (fat breakdown). Why not? Describe the metabolic route that is used to generate a glycerol compound for triacylglycerol synthesis.arrow_forwardIn considering the carbohydrate maltose... a. How many molecules of acetyl CoA are formed from its complete catabolism? b. How many rounds of Citric acid Cycle must occur to complete catabolism? c. How many rounds of electron transport chain and oxidative phosphorylation?arrow_forward
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