Briefly explain the malate-aspartate shuttle. Distinguish between this shuttle with the glycerol-phosphate shuttle based upon their transport of reducing equivalents and their potential forATP synthesis.

The electrons produced during a biochemical pathway are allowed to move across the membrane for…

Answered: Briefly explain the malate-aspartate…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Explain the purpose of the glycerol 3 phosphate shuttle (Don’t worry about the mechanism, just the purpose of the shuttle. Just one sentence here!). Suppose a cell could only rely on the glycerol 3 phosphate shuttle and not the malate-aspartate shuttle, how would that affect the amount of ATP that could be generated from the complete oxidation of 1 molecule of glucose in that cell? How would this change the amount of ATP that could be generated from the complete oxidation of 1 molecule of palmitate in this cell?
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ATP Accounting Upon digestion of starch, maltose, one of its degradation products, is further hydrolyzed into its monosaccharide components prior to intestinal absorption and entry into the glycolysis. Calculate the number of ATP molecules produced from the digestion and complete oxidation of 3 molecules of maltose considering the malate-aspartate shuttle. Answer the following items using numerical value only (e.g. 1, not "1 ATP") which will help you arrive at the final answer for this question. a. Total number of glucose molecules entering glycolysis: b. Total number of pyruvate molecules produced at the end of glycolysis: c. Total number of mitochondrial NADH produced after pyruvate is acted upon by the pyruvate dehydrogenase complex: d. Total number of CO2 released right after the pyruvate dehydrogenase complex reaction: e. Total number of acetyl CoA molecules entering the citric acid cycle: f. Total number of net cytosolic ATP molecules produced right after glycolysis: g. Total…
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Briefly explain the malate-aspartate shuttle. Distinguish between this shuttle with the glycerol phosphate shuttle based upon their transport of reducing equivalents and their potential for ATP synthesis.