Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
bartleby

Concept explainers

Question
Book Icon
Chapter 22, Problem 1P
Interpretation Introduction

Interpretation:

Match the given columns.

Concept introduction:

The process of fatty acid synthesis occurs in the cytosol of the animal cells, while it occurs in the stroma of chloroplast in the plant cells. It is a stepwise process, which occurs by the addition of two carbon units. These carbon units are provided by the acetyl-CoA, derived from glucose oxidation.

Expert Solution & Answer
Check Mark

Answer to Problem 1P

The columns are matched as given below:

a. Triacylglycerol 5. Storage form of fats
b. Perilipin 11. Lipid-droplet-associated protein
c. Adipose triglyceride lipase 1. The enzyme that initiates lipid degradation
d. Glucagon 10. Stimulates lipolysis
e. Acyl CoA synthetase 2. Activates fatty acids for degradation
f. Carnitine 6. Required for entry into mitochondria.
g. Beta-oxidation pathway 9. Means by which fatty acids are degraded
h. Enoyl CoA isomerase 3. Converts cis-Δ3 double bond into trans-Δ2 double bond
i. 2,4-dienoyl CoA reductase 4. Reduces 2,4-dienoyl intermediate to trans-Δ3-enoyl CoA
j. Methylmalonyl CoA reductase 7. Requires vitamin B12.
k. Ketone body 8. Acetoacetate.

Explanation of Solution

  1. Triacylglycerols are found in almost all body cells, especially in the liver and the intestine cells. It acts as an important fat and energy reserve in the body.
  2. Perilipin is also termed perilipin 1, PLIN, and lipid-droplet associated protein. It is encoded by PLIN gene, and they are associated with the lipid droplets at their surface.
  3. Adipose triglyceride lipase is an enzyme, which has triglyceride-specific lipase activity. The function of this enzyme is to initiate the lipid degradation process.
  4. Glucagon is a hormone which is secreted by the alpha cells of the pancreas. It functions opposite to insulin and helps in maintaining the blood glucose level. It also influences the conversion of triacylglycerols into free fatty acids and glycerol that is it stimulates lipolysis.
  5. AcylCoAsynthetase enzyme is used during the fatty acid activation. This enzyme requires ATP hydrolysis as energy to activate fatty acid and convert it into acyl-CoA.
  6. Carnitine is a carrier protein which is used to transport fatty acid from inner mitochondrial membrane to mitochondrial matrix.
  7. Beta-oxidation pathway is the process by which fatty acids are degraded. It is sequential process in which the two carbon units are removed from the carboxyl end.
  8. Enoyl CoA isomerase isomerases cis beta, gamma double bond to trans alpha, beta double bond.
  9. 2,4-dienoyl CoA reductase functions to reduce 2,4-dienoyl to trans-3-enoyl-CoA during the beta oxidation process.
  10. Methylmalonyl CoA reductase is required during the beta oxidation pathway and requires vitamin B12 as the cofactor.
  11. Ketone body in the fatty acid degradation is acetoacetate.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!
Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)
Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON