Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 20, Problem 9P
Put the following steps in the correct ordered sequence.
| a. | kinase cascade |
| b. | activation of a transcription factor |
| c. | hormone binds transmembrane receptor |
| d. | expression of target genes in the nucleus |
| e. | Ras molecular switch |
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Students have asked these similar questions
Binding of a ligand (like TGFA) to a receptor tyrosine kinase (RTK) causes all of the following except (can use cell):
OA. Dimerization of the receptor
B. Auto-phosphorylation of the receptor
O C. Activation of Ras through an interction with GRB2 (an adaptor) and SOS (a GEF) proteins.
O D. Activation of heterotrimeric G proteins
Which of the following defects in RAS would be tumorigenic? multiple answers
A.
Deletion of nucleotide binding domain
B.
Inactivation of Guanine Exchange Factor (GEF)
C.
Mutation at amino acid 61 that prevents hydrolysis of bound GTP
D.
Inactivation of GTPase Protein (GAPS)
E.
Mutation that prevents binding of GTP
Which of the following statements are correct about cytoplasmic signaling in cancer cells? Multiple answers.
A.
Only minor modifications of cell control machinery are required for normal cells to become highly proliferating cancer cells
B.
Immediate early genes are induced in the presence of protein synthesis inhibitors
C.
Many immediate -early genes are oncogenes
D.
Delayed early genes are highly expressed in the presence of protein synthesis inhibitors
E.
Delayed early genes are highly expressed in normal cells in the absence of growth factors
Chapter 20 Solutions
Genetics: From Genes to Genomes
Ch. 20 - For each of the terms in the left column, choose...Ch. 20 - Characterize the differences between tumor cells...Ch. 20 - Prob. 3PCh. 20 - Prob. 4PCh. 20 - A carcinogenic compound is placed on the skin of...Ch. 20 - You have decided to study genetic factors...Ch. 20 - B cells are specialized blood cells that secrete...Ch. 20 - Molecules outside and inside the cell regulate the...Ch. 20 - Put the following steps in the correct ordered...Ch. 20 - a. Would you expect a cell to continue or to stop...
Ch. 20 - Two different protein complexes called SCF and APC...Ch. 20 - One of the hallmarks of mitotic anaphase is the...Ch. 20 - Concerning the Tools of Genetics Box Analysis of...Ch. 20 - Are genome and karyotype instabilities...Ch. 20 - Prob. 15PCh. 20 - Why dont all loss-of-function mutations that are...Ch. 20 - Chromothripsis is a rare phenomenon, first...Ch. 20 - The chromosome 9/22 translocation associated with...Ch. 20 - A female patient 19 years old, whose symptoms are...Ch. 20 - Prob. 20PCh. 20 - A generic signaling cascade is shown in the...Ch. 20 - Neurofibromatosis type 1 NF1; also known as von...Ch. 20 - Families with germ-line BRCA1 or BRCA2...Ch. 20 - The text explained that retroviruses can cause...Ch. 20 - Hepatocellular carcinoma is the most frequent form...Ch. 20 - Suppose that instead of microarrays, you analyzed...Ch. 20 - Prob. 27PCh. 20 - Glioblastoma multiforme GBM is the most common and...Ch. 20 - a. The legend to Fig. 20.29 identifies which of...Ch. 20 - The website CBioPortal http://www.cbioportal.org...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
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