Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 19, Problem 33RA
Summary Introduction
To review:
The following:
1. The role of GLUT4 (glucose transporters) in glucose
2. The mechanism by which exercise aids in controlling type II diabetes mellitus.
Introduction:
Glucose is the main source of energy for all the cells and excess of blood glucose is stored in the form of glycogen in the liver and skeletal muscles. This stored glucose is utilized when the blood glucose level lowers down. Insulin and glucagon hormones regulate the blood glucose level. Insulin stimulates a decrease in the glucose level to the normal range whereas glucagon increases the blood glucose concentration.
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Chapter 19 Solutions
Human Physiology
Ch. 19 - Explain how the metabolic rate is influenced by...Ch. 19 - Prob. 2aCPCh. 19 - Prob. 2bCPCh. 19 - Prob. 3CPCh. 19 - Distinguish between the energy reserves and...Ch. 19 - Prob. 5CPCh. 19 - Identify the brain regions involved in hunger and...Ch. 19 - Prob. 7CPCh. 19 - Describe how the secretions of insulin and...Ch. 19 - Prob. 8bCP
Ch. 19 - Define the following terms: glycogenolysis,...Ch. 19 - Prob. 9CPCh. 19 - Prob. 10aCPCh. 19 - Prob. 10bCPCh. 19 - Explain the meaning of the terms insulin...Ch. 19 - Prob. 12aCPCh. 19 - Prob. 12bCPCh. 19 - Prob. 13aCPCh. 19 - Prob. 13bCPCh. 19 - Describe the mechanisms by which the secretion of...Ch. 19 - Prob. 15aCPCh. 19 - Prob. 15bCPCh. 19 - Prob. 15cCPCh. 19 - ln questions 1-5, match the item to the correct...Ch. 19 - Prob. 2RACh. 19 - Prob. 3RACh. 19 - Prob. 4RACh. 19 - Prob. 5RACh. 19 - Prob. 6RACh. 19 - Prob. 7RACh. 19 - Prob. 8RACh. 19 - Prob. 9RACh. 19 - The increased intestinal absorption of calcium is...Ch. 19 - Prob. 11RACh. 19 - Prob. 12RACh. 19 - Prob. 13RACh. 19 - Prob. 14RACh. 19 - Prob. 15RACh. 19 - Prob. 16RACh. 19 - Prob. 17RACh. 19 - Prob. 18RACh. 19 - Prob. 19RACh. 19 - Prob. 20RACh. 19 - Prob. 21RACh. 19 - Prob. 22RACh. 19 - Prob. 23RACh. 19 - Prob. 24RACh. 19 - Prob. 25RACh. 19 - Prob. 26RACh. 19 - Prob. 27RACh. 19 - Describe the conditions of gigantism, acromegaly,...Ch. 19 - Describe how hormones secreted by the...Ch. 19 - Prob. 30RACh. 19 - Prob. 31RACh. 19 - Prob. 32RACh. 19 - Prob. 33RACh. 19 - Prob. 34RACh. 19 - Prob. 35RACh. 19 - Prob. 36RACh. 19 - Prob. 37RACh. 19 - Prob. 38RACh. 19 - Prob. 39RACh. 19 - Prob. 40RACh. 19 - Prob. 41RACh. 19 - Prob. 42RACh. 19 - Prob. 43RA
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- Compare the localization of GLUT4 with that of GLUT2 and GLUT3, and explain why these localizations are important in the response of muscle,adipose tissue, brain, and liver to insulinarrow_forwardDiscuss briefly the principle involved in the estimation of blood glucose by the glucose oxidase method.arrow_forwardDuring the initial phase of exercise, muscles can become hypoxic which leads to the buildup of lactate. a) Fully explain how oxygen shortage can lead to the accumulation of lactate in the muscles. b) Describe how lactate (often seen as a waste product) can produce glucose via gluconeogenesis.arrow_forward
- People with non-insulin-dependent diabetes mellitus are generally not ketosis prone. This is thought to be a result of: the lack of increase in glucagons in the se individuals the presence of insulin in the individuals their obesity the fact that, their blood glucose levels do not tend to rise significantly Metabolic actions of insulin include all of the following except: increased glycogenesis decreased gluconeogenesis increased basal metabolic rate increased skeletal muscle amino acid up-take all of the above are metabolic actions of insulinarrow_forwardDescribe the effects of insulin and glucagon on glycogenmetabolismarrow_forwardMuscles may become hypoxic during the early stages of exercise, causing lactate to build up. a) Describe in detail how a lack of oxygen might cause lactate to build up in the muscles. b) Explain how lactate (typically thought of as a waste product) may be converted to glucose via gluconeogenesis.arrow_forward
- Which of the following is the correct summary of the anaerobic breakdown of glucose in the skeletal muscle? Glucose + ADP + Pi ⟶ lactate + ATP Glucose + 2ADP + 2Pi ⟶ 2 lactate + 2ATP Glucose + 2ADP + 2Pi + 2NAD+ ⟶ 2 pyruvate + 2ATP + 2NADH + 2H+ Glucose + ADP + Pi ⟶ pyruvate + ATP Glucose + 2ADP + 2Pi ⟶ 2 pyruvate + 2ATParrow_forwardExplain why insulin is required for adipocytes to synthesize triacylglycerols from fatty acids.arrow_forwardComplete the following chart about PDHK activity by determining if the molecule would be in high or low concentration or which pathway would be active. Molecule or pathway Low Energy State High Energy State Руruvate ATP/ADP Acetyl-CoA/CoA NADH/ NAD* Glycolysis/gluconeogenesis Insulin/Glucagonarrow_forward
- Name two proteins that are effectors of the insulin signaling pathway in adipocytes, liver, or muscle cells. Explain how these effector proteins address the conditions that triggered insulin release.arrow_forwardHexokinase deficiency (HKD) is a congenital disease that can disrupt intracellular glucose levels. Please provide an explanation of the diseases impact on intracellular glucose levels and the mechanism by which how GLUT1 regulates this disrupted glucose level.arrow_forwardIndividuals with McArdle’s disease often experience a “second wind” resulting from cardiovascular adjustments that allow glucose mobilized from liver glycogen to fuel muscle contraction. Explain why the amount of ATP derived in the muscle from circulating glucose is less than the amount of ATP that would be obtained by mobilizing the same amount of glucose from muscle glycogen.arrow_forward
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