Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 12.4, Problem 4COMQ
Summary Introduction
Introduction:
7 methyl guanosine is a modified purine nucleoside found in human urine, as a biomarker for some type of cancer. Thus, they could also be used as a type of cancer detection. Cancer is a disease, wherein the cells grow uncontrollably.
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The codon and anticodon are base-paired together during the process of translation. Which of the following is correct regarding the relationship between anticodon and codon?
A. The tRNA anticodon UCU pairs with the AGA mRNA codon.
B. The tRNA anticodon is read from the 5’ to the 3’ end.
C. A tRNA anticodon can pair with only one mRNA codon.
D. The mRNA codon ACG base pairs with the tRNA anticodon TGC.
Which translation factor mediates the aminoacyl-tRNA entry into the A site of the ribosome?
A. EF-Tu
B. EF-Ts
C. EF-G
D. IF1
Which of the following is not a function of the 5’ cap and 3’ poly-A tail of a mature eukaryotic mRNA molecule?
a. To facilitate splicing
b. To prevent mRNA degradation
c. To aid export of the mature transcript to the cytoplasm
d. To aid ribosome binding to the transcript
Chapter 12 Solutions
Genetics: Analysis and Principles
Ch. 12.1 - 1. Which of the following base sequences is used...Ch. 12.1 - Prob. 2COMQCh. 12.2 - With regard to a promoter, a transcriptional start...Ch. 12.2 - Prob. 2COMQCh. 12.2 - 3. Sigma factor is needed during which stage(s) of...Ch. 12.2 - A uracil-rich sequence occurs at the end of the...Ch. 12.3 - Which RNA polymerase in eukaryotes is responsible...Ch. 12.3 - Prob. 2COMQCh. 12.3 - Prob. 3COMQCh. 12.3 - Prob. 4COMQ
Ch. 12.4 - Which of the following are examples of RNA...Ch. 12.4 - A ribozyme is a. a complex between RNA and a...Ch. 12.4 - Prob. 3COMQCh. 12.4 - Prob. 4COMQCh. 12.5 - 1. Which of the following is not a key difference...Ch. 12 - Prob. 1CONQCh. 12 - Prob. 2CONQCh. 12 - Prob. 3CONQCh. 12 - Prob. 4CONQCh. 12 - 5. Mutations in bacterial promoters may increase...Ch. 12 - Prob. 6CONQCh. 12 - 7. In Chapter 9, we considered the dimensions of...Ch. 12 - 8. A mutation within a gene sequence changes the...Ch. 12 - Prob. 9CONQCh. 12 - At the molecular level, describe how factor...Ch. 12 - Prob. 11CONQCh. 12 - What is the complementarity rule that governs the...Ch. 12 - 13. Describe the movement of the open complex...Ch. 12 - 14. Describe what happens to the chemical bonding...Ch. 12 - Prob. 15CONQCh. 12 - Prob. 16CONQCh. 12 - Prob. 17CONQCh. 12 - Mutations that occur at the end of a gene may...Ch. 12 - If the following RNA polymerases were missing from...Ch. 12 - 20. What sequence elements are found within the...Ch. 12 - 21. For each of the following transcription...Ch. 12 - 22. Describe the allosteric and torpedo models for...Ch. 12 - Which eukaryotic transcription factor(s) shown in...Ch. 12 - 24. The initiation phase of eukaryotic...Ch. 12 - A eukaryotic protein-encoding gene contains two...Ch. 12 - 26. Describe the processing events that occur...Ch. 12 - Prob. 27CONQCh. 12 - Prob. 28CONQCh. 12 - Prob. 29CONQCh. 12 - Prob. 30CONQCh. 12 - 31. In eukaryotes, what types of modifications...Ch. 12 - Prob. 32CONQCh. 12 - Prob. 33CONQCh. 12 - 34. Figure 12.21 shows the products of alternative...Ch. 12 - 35. The processing of ribosomal RNA in eukaryotes...Ch. 12 - Prob. 36CONQCh. 12 - Prob. 37CONQCh. 12 - After the intron (which is in a lariat...Ch. 12 - Prob. 1EQCh. 12 - 2. Chapter 21 describes a technique known as...Ch. 12 - Prob. 3EQCh. 12 - As described in Chapter 21 and in experimental...Ch. 12 - Prob. 5EQCh. 12 - Prob. 6EQCh. 12 - 1. Based on your knowledge of introns and pre-mRNA...Ch. 12 - Discuss the types of RNA transcripts and the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following is the mRNA coding for the peptide trp-met-gly- ser-his? A. 5'GGUGUAUGGUCUUAC-3' B. 5'-CAUUCUGGUAUGUGG-3' C. 5'-UGGAUGGGUUCUCAU-3' D. 3'-UGGAUGGGUUCUCAU-5' E. cannot be determined since the genetic code is degeneratearrow_forwardWhich of the following mutations is most likely to cause a single amino acid difference during the translation of mRNA into protein? A. Single base-pair insertion B. Single base-pair deletion C. Mutations in regulatory sites D. Base-pair substitutionarrow_forwardThe initiation factors a. help assembling both ribosomal subunits with mRNA and initiator tRNA b. help with the peptide bond formation c. help starting the translation elongation d. are responsible for the initiation of ribosome translocationarrow_forward
- Of the following, which is a modification made to the pre-mRNA of eukaryotes before translation? a. The 5’ end receives a poly-A tail b. All of the above c. The 3’ end receives a cap d. Introns are cut out and exons are spliced togetherarrow_forwardThe release factors RF1 and RF2 are required for a. translation termination b. the realease of the aminoacid from the tRNA c. translation elongation d. translation initiationarrow_forwardDuring initiation of translation, a is positioned first at the start codon. A. fMet-tRNA B. Val-tRNA C. Cys-tRNA D. Ser-tRNAarrow_forward
- Arrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forwardA principle function of 5' and 3' end modifications of eukaryotic mRNA is: a. to ensure that all nucleotides are phosphorylated b. to protect RNA from nucleolytic degradation c. to guide the removal of introns d. to serve as binding sites for translation release factorsarrow_forwardA nonsense mutation Select one: a. results in a larger protein being produced from the mutated gene b. will lead to premature termination of translation c. is the same as a silent mutation d. will lead to the premature termination of transcriptionarrow_forward
- Why might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardDuring translation, when a stop codon is read on the mRNA strand at the ribosome... a the mRNA is digested by a protease complex b a repressor attached to the ribosome that inhibits the movement of the ribosome along the mRNA c the enzyme helicase binds to terminate the polypeptide d a release factor enters the A site of the ribosome and stimulates the disassembly of the translation complex Codons are... a triplets coding for a single amino acid. b redundant in their coding for various amino acids. c matched with anticodons during translation d triplets found on transfer RNA Question 6 (1 point) In order to produce many copies of the same protein in a short period of time, the cell uses... a intron self-splicing. b many RNA polymerase molecules to produce multiple mRNA transcripts at the same time. c single-unit ribosomes for high speed translation. d codon-anticodon reciprocal…arrow_forwardWhich of the following statements about RNA processing in eukaryotes is INCORRECT? A. The excision of introns from pre-mRNA is the only modification required to produce a mature mRNA. B. A protein/RNA complex is used to remove introns from the pre-mRNA. C. A poly A tail is added on to the 3′ end of the mRNA. D. A 7-methylguanosine cap is added on to the 5′end of the mRNA. E. Modification occurs in the nucleus.arrow_forward
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