Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 11, Problem 2P
Would you characterize the pattern of inheritance of anonymous DNA polymorphisms as recessive, dominant, incompletely dominant, or codominant?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Why must the carrier of a genetic disease be heterozygous?
According to the pedigree below, what mode of inheritance is occurring?
A)Autosomal dominant
B)Autosomal recessive
C)X-linked
Why are the concepts of variable expressivity, incomplete penetrance, and delayed age of onset so important in relation to genetic diseases?
Chapter 11 Solutions
Genetics: From Genes to Genomes
Ch. 11 - Choose the phrase from the right column that best...Ch. 11 - Would you characterize the pattern of inheritance...Ch. 11 - Would you be more likely to find single nucleotide...Ch. 11 - A recent estimate of the rate of base...Ch. 11 - If you examine Fig. 11.5 closely, you will note...Ch. 11 - Approximately 50 million SNPs have thus far been...Ch. 11 - Mutations at simple sequence repeat SSR loci occur...Ch. 11 - Humans and gorillas last shared a common ancestor...Ch. 11 - In 2015, an international team of scientists...Ch. 11 - Using PCR, you want to amplify an approximately 1...
Ch. 11 - Prob. 11PCh. 11 - The previous problem raises several interesting...Ch. 11 - You want to make a recombinant DNA in which a PCR...Ch. 11 - You sequence a PCR product amplified from a...Ch. 11 - Prob. 15PCh. 11 - The trinucleotide repeat region of the Huntington...Ch. 11 - Sperm samples were taken from two men just...Ch. 11 - Prob. 18PCh. 11 - a. It is possible to perform DNA fingerprinting...Ch. 11 - On July 17, 1918, Tsar Nicholas II; his wife the...Ch. 11 - The figure that follows shows DNA fingerprint...Ch. 11 - Microarrays were used to determine the genotypes...Ch. 11 - A partial sequence of the wild-type HbA allele is...Ch. 11 - a. In Fig. 11.17b, PCR is performed to amplify...Ch. 11 - The following figure shows a partial microarray...Ch. 11 - Scientists were surprised to discover recently...Ch. 11 - The microarray shown in Problem 25 analyzes...Ch. 11 - The figure that follows shows the pedigree of a...Ch. 11 - One of the difficulties faced by human geneticists...Ch. 11 - Now consider a mating between consanguineous...Ch. 11 - The pedigree shown in Fig. 11.22 was crucial to...Ch. 11 - You have identified a SNP marker that in one large...Ch. 11 - The pedigrees indicated here were obtained with...Ch. 11 - Approximately 3 of the population carries a mutant...Ch. 11 - The drug ivacaftor has recently been developed to...Ch. 11 - In the high-throughput DNA sequencing protocol...Ch. 11 - A researcher sequences the whole exome of a...Ch. 11 - As explained in the text, the cause of many...Ch. 11 - Figure 11.26 portrayed the analysis of Miller...Ch. 11 - A research paper published in the summer of 2012...Ch. 11 - Table 11.2 and Fig. 11.27 together portray the...Ch. 11 - The human RefSeq of the entire first exon of a...Ch. 11 - Mutations in the HPRT1 gene in humans result in at...Ch. 11 - Prob. 44P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- For a particular gene, homozygous dominant AA and heterozygous Aa individuals produce green pigment, while homozygous recessive aa individuals produce yellow pigment. During the course of your research you discover the a1 allele that contains a class IlI transposon insertion. Allele A is dominant to a1. Which genotype is capable of producing a mixture of green and yellow pigment?arrow_forwardA young lady requested pre-marital genetic counselling because her sister had died in infancy of gangliosidosis, an autosomal recessive disease. What is the risk that this young lady has similarly affected offspring? What advice should be given?arrow_forwardAssume that a gene controls the expression of a trait in which affected children occur only in families where one or both parents are also affected; children who are normal may have parents who are (1) both normal, (2) one normal and one affected, or (3) both affected. Is the gene for the affected condition completely dominant, co-dominant, incompletely dominant or recessive?arrow_forward
- The Pedigree shown below shows what type of inheritance? a) Autosomal Dominant O b) Sex Linked Recessive O c) Sex Linked Dominant d) Autosomal Recessivearrow_forwardWhich of the following genetic diseases is/are inherited as an autosomal recessive trait: phenylketonuria, Huntington’s disease, Tay-Sachs disease?arrow_forwardMany genetic disorders exhibit locus heterogeneity. Define andgive two examples of locus heterogeneity. How does locus heterogeneityconfound a pedigree analysis?arrow_forward
- Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations and sometimes loss of awareness. For epilepsy, the concordance values are 72% for monozygotic twins and 15% for dizygotic twins. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.arrow_forwardCould the trait indicated in the pedigree above be caused by an autosomal gene? Hint: consider each type of autosomal inheritance and see if it could explain the inheritance of the trait. a) Yes, an autosomal dominant gene could explain this trait. b) Yes, an autosomal recessive gene could explain this trait. c) No, an autosomal gene could not account for this pedigree. d) Yes, A and B are true.arrow_forwardWhat is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.arrow_forward
- Circle any inheritance patterns that could explain this pedigree. Assume individuals marrying into the family do not have a mutant allele. Please refer to the image attached. A) Paternally imprinted B) Maternally imprinted C) Maternal inheritance D) Autosomal recessive E) Autosomal dominant F) X-linked recessive G) X-linked dominantarrow_forwardIn a multigenerational study of a family, 8% of the males and 8% of the females have red hair. What may be the cause of this? A)Autosomal inheritance B)Environmental influence C)Sex-linked inheritance D)Non-somatic inheritancearrow_forwardRegarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY