Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Chapter 4, Problem 8P
Interpretation Introduction
Interpretation:
The reason for the denaturation or melting of DNA during heating should be explained.
Concept introduction:
Denaturation is a process of breaking weak bonds or linkages within molecules of protein in natural states.
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TRUE OR FALSE. Studies have confirmed that damaged to both the double strands can be reversed via single stranded annealing.
TRUE or FALSE. If false, write the word/s that make(s) the statement incorrect.
1.The 2 subunits of DNA PoI II are called clamp loader and sliding clamps.
2. In eukaryotes, replication and transcription occur in the nucleus, while translation occurs in the cytoplasm.
N.
NH
2. One of the key pieces of information that Watson
and Crick used in determining the secondary
structure of DNA came from experiments done by E.
Chargaff, in which he studied the nucleotide
composition of DNA from many different species.
O=P-OCH,
N.
`NH,
HN
он
O= P- OCH,
NH,
Chargaff noted that the molar quantity of A_was
always approximately equal to the molar quantity of
T. and the molar quantity of C was always
approximately equal to the molar quantity of G. How
were Chargaff's results explained by the
structural model of DNA proposed by Watson
and Crick?
N
OH
N.
O= P-OCH,
OH
OH
Chapter 4 Solutions
Biochemistry
Ch. 4 - Prob. 1PCh. 4 - Prob. 2PCh. 4 - Prob. 3PCh. 4 - Prob. 4PCh. 4 - Prob. 5PCh. 4 - Prob. 6PCh. 4 - Prob. 7PCh. 4 - Prob. 8PCh. 4 - Prob. 9PCh. 4 - Prob. 10P
Ch. 4 - Prob. 11PCh. 4 - Prob. 12PCh. 4 - Prob. 13PCh. 4 - Prob. 14PCh. 4 - Prob. 15PCh. 4 - Prob. 16PCh. 4 - Prob. 17PCh. 4 - Prob. 18PCh. 4 - Prob. 19PCh. 4 - Prob. 20PCh. 4 - Prob. 21PCh. 4 - Prob. 22PCh. 4 - Prob. 23PCh. 4 - Prob. 24PCh. 4 - Prob. 25PCh. 4 - Prob. 26PCh. 4 - Prob. 27PCh. 4 - Prob. 28PCh. 4 - Prob. 29PCh. 4 - Prob. 30PCh. 4 - Prob. 31PCh. 4 - Prob. 32PCh. 4 - Prob. 33PCh. 4 - Prob. 34PCh. 4 - Prob. 35PCh. 4 - Prob. 36PCh. 4 - Prob. 37PCh. 4 - Prob. 38PCh. 4 - Prob. 39PCh. 4 - Prob. 40PCh. 4 - Prob. 41PCh. 4 - Prob. 42PCh. 4 - Prob. 43PCh. 4 - Prob. 44PCh. 4 - Prob. 45PCh. 4 - Prob. 46PCh. 4 - Prob. 47PCh. 4 - Prob. 48PCh. 4 - Prob. 49PCh. 4 - Prob. 50PCh. 4 - Prob. 51PCh. 4 - Prob. 52P
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- What is the melting temp. of the following double-stranded DNA fragment TCAAAAATCGAATATTTGCTTATCTA AGTTTTTAGCTTATAAACGAATAGATarrow_forwardPlease help me with this please. I really don't know how to make this. I really do appreciate you're help. 1. make a simple illustration to relate the different kinds of DNA to its function.arrow_forwardTrue or False. Each time the genome is replicated, half the newly synthesized DNA is stitched together from Okazaki fragments. Explain your answer in 1-2 sentences.arrow_forward
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- True or False. The first step of DNA repair is catalyzed by enzymes unique to the process and more general enzymes catalyze later steps of the process.arrow_forwardPlease draw or send me a picture of the structure of DNA and label the parts. Thank you very much.arrow_forwardCentral Dogma Theory (Chapter 8.1, 8.2, 8.3, 8.4, 8.5, 8.6, & 8.7) o Page 7: Draw a double-stranded segment of DNA and label phosphate groups, sugars, and the 4 bases (adenine, guanine, cytosine, & thymine) correctly paired.arrow_forward
- This is DNA. Locate the nitrogen bases (nitrogens are blue). Where are they located in the molecule?Locate the sugars and phosphates, and describe their location. Adjacent nucleotides are linked by covalent phosphodiester bonds (-O-P-O-) produced by a condensation reaction. What parts of the adjacent nucleotides are linked by phosphodiester bonds?Two nitrogenous bases extending towards the middle of the double helix. Are there any covalent bonds between these bases?If there are no covalent bonds between these bases, what other kinds of bonds might hold the two strands of the double helix together?arrow_forwardRNA- degrading enzyme. DNA Helicase Deoxyribonuclease Protease Ribonucleasearrow_forwardClose contact. Examination of the structure of DNA polymerases bound to nucleotide analogs reveals that conserved residues come within van der Waals contact of C-2'C-2' of the bound nucleotide. What is the potential significance of this interaction?arrow_forward
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