(a) Interpretation: The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained. Concept introduction: A sequence of three DNA or RNA nucleotides is called a codon. The three- nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

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Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

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i. A schematic structure of the subunit of hemerythrin (an oxygen-binding protein from invertebrate animals) is shown to the right. (a) It has been found that in some of the a-helical regions of hemerythrin, about every third or fourth amino acid residue is a hydrophobic one. Suggest a structural reason for this finding. (b) What would be the effect of a mutation that placed a proline residue at point A in the structure?

GT 3 A. Write the structure of the pentapeptide GLDSC. B. What is the complete name of this pentapeptide? Show a tertiary structure of ACGGC after a disulfide bond forms. A sample of an unknown peptide was divided into two aliquots. One aliquot was treated with trypsin; the other was treated with cyanogen bromide. Given the following sequences (N-terminal to C- terminal) of the resulting fragments, deduce the sequence of the original peptide. Trypsin treatment Asn-Thr-Trp-Met-lle-Lys Gly-Tyr-Met-Gln-Phe Val-Leu-Gly-Met-Ser-Arg Cyanogen bromide treatment Gln-Phe Val-Leu-Gly-Met lle-Lys-Gly-Tyr-Met Ser-Arg-Asn-Thr-Trp-Met

AAAGAGAAAAGAAUA to AAAGAGAAAUGAAUA. Suppose the codon sequence has a single base pair mutation If the old protein sequence was Lys-Glu-Lys-Arg-Ile, what will be the new sequence encoded by the mutant gene? (Use the 3-letter amino acid abbreviations with hyphens and no spaces in between, i.e. Ser-Asn-Tyr-Leu-Pro.) Submit Answer Retry Entire Group No more group attempts remain

Answer 2

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Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

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Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

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Answer 4

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Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

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Answer 7

Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Answer 8

Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Answer 9

Chapter 4, Problem 47P

Interpretation Introduction

(a)

Interpretation:

The reason for the doubt in the reported amino acid substitution by a molecular geneticist needs to be explained.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Answer 10

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Answer 11

Interpretation Introduction

(b)

Interpretation:

The amino acid sequence, more palatable to the molecular geneticist needs to be determined.

Concept introduction:

A sequence of three DNA or RNA nucleotides is called a Codon. The three-nucleotide sequence or codon corresponds to a specific amino acid, and these codons are interpreted by the tRNA. The tRNA also contains the anticodon which recognizes and interprets the codons on the mRNA. The tRNA binds to its corresponding codon on the ribosome and they decode the mRNA until the whole sequence is coded. The sequences can be mutated, and they can give rise to new proteins and genes.

Answer 12

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Answer 15

Ch. 4 - Prob. 1P Ch. 4 - Prob. 2P Ch. 4 - Prob. 3P Ch. 4 - Prob. 4P Ch. 4 - Prob. 5P Ch. 4 - Prob. 6P Ch. 4 - Prob. 7P Ch. 4 - Prob. 8P Ch. 4 - Prob. 9P Ch. 4 - Prob. 10P

Solution Summary: The author explains the reason for the doubt in the reported amino acid substitution by a molecular geneticist.

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