Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Textbook Question
Chapter 4, Problem 3RA
Which of these statements about lactate dehydrogenase is true?
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Which of the following statements about the "central role" of TCA is/are correct?
a. Some metabolic intermediates of TCA are used as non-carbohydrate sources for gluconeogenesis.
b. β-oxidation of lipids produces acetyl-CoA that can enter TCA.
c. All metabolic intermediates in TCA are used in the biosynthesis of amino acids.
d. Degraded amino acids are converted to metabolic intermediates of TCA, then to ketone bodies.
Which of the following statements regarding formation of glucose - 1 - phosphate from
glycogen is NOT CORRECT?
A. It triggered by low blood glucose
B. It requires ATP hydrolysis
C. It is catalyzed by glycogen phosphorylase enzyme
D. It involves the cleavage of an alpha (1- 4) bond
Which of the following statements concerning gluconeogenesis is NOT true?
a.
Gluconeogenesis is to make glucose from glycogen.
b.
Many of the reactions of gluconeogenesis are glycolytic reactions going in reverse.
c.
The process of gluconeogenesis consumes ATP.
d.
The process of gluconeogenesis is regulated by ATP.
e.
Gluconeogenesis maintains the blood glucose level long after all dietary glucose has been absorbed and oxidized.
Chapter 4 Solutions
Human Physiology
Ch. 4 - Use the lock-and-key model to explain how enzymes...Ch. 4 - Explain how enzymes are named, and the nature of...Ch. 4 - Draw graphs to represent the effects of changes in...Ch. 4 - Prob. 4CPCh. 4 - Prob. 5aCPCh. 4 - Prob. 5bCPCh. 4 - Prob. 5cCPCh. 4 - Prob. 6aCPCh. 4 - Define the terms exergonic reaction and endergonic...Ch. 4 - Prob. 7aCP
Ch. 4 - Prob. 7bCPCh. 4 - Which of these statements about enzymes is...Ch. 4 - Which of these statements about enzyme-catalyzed...Ch. 4 - Which of these statements about lactate...Ch. 4 - In a metabolic pathway, a. the product of one...Ch. 4 - In an inborn error of metabolism,
a. a genetic...Ch. 4 - Which of these represents an endergonic...Ch. 4 - Which of these statements about ATP is true? a....Ch. 4 - When oxygen is combined with 2 hydrogens to make...Ch. 4 - Enzymes increase the rate of chemical reactions...Ch. 4 - According to the law of mass action, which of...Ch. 4 - Explain the relationship between an enzyme's...Ch. 4 - Explain how the rate of enzymatic reactions may be...Ch. 4 - Explain how end-product inhibition represents a...Ch. 4 - Prob. 14RACh. 4 - The coenzymes NAD and FAD can "shuttle" hydrogens...Ch. 4 - Prob. 16RACh. 4 - Why do we need to eat food containing niacin and...Ch. 4 - Metabolic pathways can be likened to intersecting...Ch. 4 - Prob. 19RACh. 4 - Suppose you come across a bottle of enzyme tablets...Ch. 4 - Describe the energy transformations that occur...Ch. 4 - Use the reversible reactions involving the...Ch. 4 - Use the graph here and in figure 4.4 to answer the...Ch. 4 - Use the graph here and in figure 4.4 to answer the...Ch. 4 - Prob. 25RACh. 4 - Prob. 26RACh. 4 - Prob. 27RA
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- Which of the following statements concerning the enzyme regulation is CORRECT? Select one: A. Citrate is the allosteric inhibitor of hexokinase. B. AMP is the alloseric activator of pyruvate dehydrogenase. C. Glucose-6-phosphate is the allosteric activator for phosphofructokinase. D. ATP is the activator of pyruvate kinase.arrow_forwardWhich of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalasearrow_forwardWhich of the following is the product of the oxidation of glucose at C1 & 6? A. Sorbitol B. glucuronic acid C. saccharic acid D. gluconic acid E. none of thesearrow_forward
- Which of the following is true concerning the function of lipoic acid in pyruvate metabolism? a. transfer of acetyl groups b. pyruvate decarboxylation c. conversion of pyruvate to lactate d. oxidation of FADH2 to yield NADHarrow_forwardWhich of the following statements is true of the β - oxidation of an unsaturated fatty acid? a. It is identical to the β-oxidation of a saturated fatty acid. b. It involves an extra step to convert a cis double bond to a trans double bond. c. It involves an extra step to convert a trans double bond to a cis double bond. d. It is completely different from the β-oxidation of a saturated fatty acid.arrow_forwardWhich of the following is the chemical end product of fatty-acids metabolized in the beta-oxidation pathway? Select one: a. Beta-carotine b. Free-radicals c. Lactic acid d. Acetyl-CoA e. Pyruvatearrow_forward
- Which of the following is NOT TRUE about fatty acid biosynthesis? A. 8 NADPH is used to produce palmitate. B. The growing fatty acid chain is elongated by the sequential addition of two-carbon units. C. The process is repeated 7 times to produce palmitate. D. The process occurs in the cytosol.arrow_forwardWhich of the following is a substrate for glycogen synthase? a. UTP-glucose b. Glucose 1-phosphate c. CDP-glucose d. UDP-glucosearrow_forwardWhich of the following statements is/are FALSE about glycolysis? A. It is an anaerobic process. B. Some steps occur in cytosol, others in mitochondria. C. It is the conversion of glucose to lactate or ethanol. D. It is the 1st stage of glucose metabolism.arrow_forward
- Which one of the following statements concerning gluconeogenesis is correct? a. It is inhibited by elevated levels of acetyl CoA. b. It occurs in muscle. c. It is important in maintaining blood glucose during normal overnight fast. d. It is stimulated by fructose 2,6-bisphosphate.arrow_forwardWhich of the following produces the highest number of reducing equivalent molecules per mole of a saturated 10 carbon fatty acid chain in aerobic conditions? A. Oxidation of Malate to Oxaloacetate B. the Electron Transport Chain C. Oxidation of a-Ketoglutarate to Succinyl-COA D. the B-Oxidation "spiral"arrow_forwardA patient complains of painful muscle cramps when performing strenuous physical exercise. A muscle biopsy indicates a higher than normal concentration of muscle glycogen. a. Which enzyme of glycogen metabolism is affected? b. Discuss how the defect of this enzyme affects glycogen metabolism.arrow_forward
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