Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 4, Problem 12RA
Explain how the
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Discuss the different factors affecting the rate of an enzymatic reaction.
Describe the role that compartmentation plays in the regulation of metabolic pathways. Provide several examples.
1) Define the following terms:
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Anaerobic:
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2) Briefly explain why oxidation-reduction reactions are important in metabolism.
Chapter 4 Solutions
Human Physiology
Ch. 4 - Use the lock-and-key model to explain how enzymes...Ch. 4 - Explain how enzymes are named, and the nature of...Ch. 4 - Draw graphs to represent the effects of changes in...Ch. 4 - Prob. 4CPCh. 4 - Prob. 5aCPCh. 4 - Prob. 5bCPCh. 4 - Prob. 5cCPCh. 4 - Prob. 6aCPCh. 4 - Define the terms exergonic reaction and endergonic...Ch. 4 - Prob. 7aCP
Ch. 4 - Prob. 7bCPCh. 4 - Which of these statements about enzymes is...Ch. 4 - Which of these statements about enzyme-catalyzed...Ch. 4 - Which of these statements about lactate...Ch. 4 - In a metabolic pathway, a. the product of one...Ch. 4 - In an inborn error of metabolism,
a. a genetic...Ch. 4 - Which of these represents an endergonic...Ch. 4 - Which of these statements about ATP is true? a....Ch. 4 - When oxygen is combined with 2 hydrogens to make...Ch. 4 - Enzymes increase the rate of chemical reactions...Ch. 4 - According to the law of mass action, which of...Ch. 4 - Explain the relationship between an enzyme's...Ch. 4 - Explain how the rate of enzymatic reactions may be...Ch. 4 - Explain how end-product inhibition represents a...Ch. 4 - Prob. 14RACh. 4 - The coenzymes NAD and FAD can "shuttle" hydrogens...Ch. 4 - Prob. 16RACh. 4 - Why do we need to eat food containing niacin and...Ch. 4 - Metabolic pathways can be likened to intersecting...Ch. 4 - Prob. 19RACh. 4 - Suppose you come across a bottle of enzyme tablets...Ch. 4 - Describe the energy transformations that occur...Ch. 4 - Use the reversible reactions involving the...Ch. 4 - Use the graph here and in figure 4.4 to answer the...Ch. 4 - Use the graph here and in figure 4.4 to answer the...Ch. 4 - Prob. 25RACh. 4 - Prob. 26RACh. 4 - Prob. 27RA
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- Discuss several ways in which metabolic pathways are controlled or regulated.arrow_forwardDiscuss the different factors affecting the rate of an enzymatic reaction. Explain enzyme kinetics including zero-order and first-order kinetics.arrow_forwardA plot of the velocity v, or rate, of an enzymatic reaction vs. the substrate concentration [S] that is sigmoid or S abaned instead of hyperbolic is characteristic of: a) b) allosteric enzymes modulator proteins isozymes proenzymes zymogensarrow_forward
- Define the following as they apply to an enzymatic reaction. Give an example of each. a. Enzyme-limited: b. Substrate-limited:arrow_forwardDescribe an example of when large conformational changes that occur during an enzymatic reaction cycle are used to drive other processes.arrow_forwardB) Read the situations below and indicate which of the four methods of enzyme regulation is occurring for each. a) The energy-carrying molecule ATP is made by the enzyme ATP synthase. Muscle cells use a lot of energy and also have higher amounts of the ATP synthase enzyme than many ouier cem types. General mechanism of enzyme regulation: /1 b) Prostaglandins are messenger molecules involved in the inflammatory response, as well as th perception of pain. They are synthesized from polyunsaturated fatty acid substrates by an enzyn called cyclo-oxygenase. "Ibuprofen" is the active ingredient in a variety of anti-inflammatory medications such as Motrin® and Advil®. It reduces pain and swelling by binding to a hydrophobic channel in the active site of cyclo-oxygenase, blocking the polyunsaturated fatty acids from binding to the enzyme, and therefore stopping production of prostaglandins. General mechanism of enzyme regulation: a) In point form, describe the steps by which ATP is produced…arrow_forward
- Indicate whether the following statements are true or false:- a) The pentose phosphate pathway of glucose oxidation can lead to the release of energy. b) NAD + is a coenzyme of transketolase.arrow_forwardDetermine the class of enzyme that is most likely to catalyze each of the following reactions, see bottom Figure 6D:arrow_forwardBriefly, outline the process of the oxidative phosphorylationarrow_forward
- Describe how enzymes contribute to metabolic processes, how they act as catalysts, the basis for their specificity, and the role of energy carriers and co-enzyme A in enzymatic processes.arrow_forwardDefine beta-(b -)oxidationarrow_forwardDiscuss the role of enzymes in metabolic regulation by describing the following five mechanisms.11.1Cascade systems11.2 Futile cycle11.3Cellular compartmentalization 11.4 Covalent modification11.5 Zymogensarrow_forward
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