Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 26, Problem 14CONQ
Describe the molecular features of the homeobox and homeodomain. Explain how these features are important in the function of homeotic genes.
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Explain the function of the homeobox sequence in a homeotic gene.
WRT is a gene in C. elegans worms which is normally expressed in a specific stage of development.
Worms without this gene (wrt-/wrt- genotype) survive, but grow too large, never develop some
parts of their anatomy. Over-expression of WRT results in a different phenotype: the worms have
stunted growth, developing mature anatomical structures too early in their growth. The following
experiments were used to learn how WRT is regulated.
a.
Several genetic loci that are also involved in development in the worm are suspected of being
regulators of WRT. Mating experiments shows that some of these genes have epistatic
relationships with WRT, and others don't. Which are likely to be WRT regulators?
i. Genes epistatic to WRT are unlikely to regulate WRT
ii. Genes epistatic to WRT are likely to regulate WRT
iii. Epistasis cannot tell us whether another gene is in the same pathway as WRT
b. Deletion of locus 1 in a WRT wildtype background causes the wrt- associated phenotype (large
but…
Categorize each statement as an example of adhesion, communication, or differentiation.
Statement
During animal development, proliferating cells become organized into
sheets of cells called epithelia. Cadherins play and essential role in
maintaining the integrity of these sheets in a process known as:
Complex multicellular organisms rely on signaling molecules
synthesized by one cell to bind to receptors on the surface of a second
cell to regulate gene expression. This type of interaction between two
different cells is a form of:
The human body contains 200 distinct cell types, yet each cell contains
the same genome. The process by which each cell adopts a specific fate
is known as:
differentiation
Answer Bank
adhesion
communication
Category
Chapter 26 Solutions
Genetics: Analysis and Principles
Ch. 26.1 - Prob. 1COMQCh. 26.1 - Prob. 2COMQCh. 26.1 - Which of the following is the correct order for...Ch. 26.2 - Prob. 1COMQCh. 26.2 - Prob. 2COMQCh. 26.2 - Prob. 3COMQCh. 26.2 - Prob. 4COMQCh. 26.3 - Prob. 1COMQCh. 26.3 - Prob. 2COMQCh. 26.3 - 3. Myogenic bHLH proteins are ___________ that...
Ch. 26.4 - Prob. 1COMQCh. 26.4 - Prob. 2COMQCh. 26.5 - 1. A key event that initially determines female or...Ch. 26.5 - Prob. 2COMQCh. 26 - 1. What four types of cellular processes must...Ch. 26 - Prob. 2CONQCh. 26 - Prob. 3CONQCh. 26 - 4. Which of the following statement(s) is/are true...Ch. 26 - Discuss the morphological differences between the...Ch. 26 - Prob. 6CONQCh. 26 - Explain what a morphogen is, and describe how it...Ch. 26 - 8. What is positional information? Discuss three...Ch. 26 - Prob. 9CONQCh. 26 - Prob. 10CONQCh. 26 - 11. Describe the function of the Bicoid protein....Ch. 26 - With regard to development, what are the roles of...Ch. 26 - Discuss the role of homeotic genes in development....Ch. 26 - Describe the molecular features of the homeobox...Ch. 26 - What would you predict to be the phenotype of...Ch. 26 - Prob. 16CONQCh. 26 - If a mutation in a homeotic gene produced the...Ch. 26 - 18. Explain how loss-of-function mutations in the...Ch. 26 - What is the difference between a maternal-effect...Ch. 26 - Prob. 20CONQCh. 26 - Prob. 21CONQCh. 26 - Prob. 22CONQCh. 26 - 23. Discuss the similarities and differences...Ch. 26 - 24. What is cell differentiation? Discuss the role...Ch. 26 - Prob. 25CONQCh. 26 - What is a totipotent cell? In each of the...Ch. 26 - 27. What is a meristem? Explain the role of...Ch. 26 - Prob. 28CONQCh. 26 - Predict the phenotypic consequences of each of the...Ch. 26 - 30. Explain how alternative splicing affects sex...Ch. 26 - Prob. 1EQCh. 26 - Compare and contrast the experimental advantages...Ch. 26 - 3. What is meant by the term cell fate? What is a...Ch. 26 - 4. Explain why a cell lineage diagram is necessary...Ch. 26 - Explain the rationale behind the use of the bag of...Ch. 26 - Prob. 6EQCh. 26 - Take a look at question 2 in More Genetic TIPS...Ch. 26 - All of the homeotic genes inDrosophilahave been...Ch. 26 - Prob. 9EQCh. 26 - wo techniques commonly used to study the...Ch. 26 - Prob. 11EQCh. 26 - Prob. 12EQCh. 26 - 13. Another way to study the role of proteins...Ch. 26 - 14. Why have geneticists used reverse genetics to...Ch. 26 - Prob. 1QSDCCh. 26 - Prob. 2QSDCCh. 26 - Prob. 3QSDC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Please explain the role of gene expression in the process of a stem cell differentiating into a neuron rather than a liver cell. Hint: use the terms "serial activation of a subset of genes" and "master regulatory gene".arrow_forwardexamine the process of gene expression. Include the following: Explain the regulation of gene expression in eukaryotic cells. Discuss mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA? Explain how cancer is formed. Describe genetic changes found in cancer cells and how these changes lead to alterations in cell behavior. Determine whether proteome data can be utilized in genetic disorder diagnosis. Relate the Human Genome Project data to the analysis of cancer genes. Relates the Human Genome Project's utility in pharmacogenomics and personalized medicine to diagnose and treat cancerarrow_forwardHousekeeping genes that code for enzymes such as those that provide energy via glycolysis are expressed in active cells only such as muscle and nerve cells while genes coding for other proteins are expressed in all kinds of cells. Select one: True Falsearrow_forward
- What types of global regulatory mechanisms might a cell use to control the changes in gene expression that occur during attachment? How will the cell sense that it is attached and what ways does it have to turn genes on or off to take advantage of the situation? Give examples to illustrate your point.arrow_forwardexplain which controls over gene expression are likely to be very brief, which may be long lasting, and why they differ?arrow_forwardExpression of a homeotic gene in the wrong tissue inDrosophila results in the development of an inappropriatebody part from that tissue. Explain why this happens andhow it shows that homeotic genes are positive regulators ofdevelopmental pathways.arrow_forward
- clarify how wild-type alleles of genes control cell growth, cell communication, and the emergence of specialized cells, tissues, and organs.arrow_forwardExplain circadian rhythms in terms of gene expression.arrow_forwardLong non-coding RNAs (lncRNA) can act as a scaffold to form protein/RNA complexes that regulate gene expression? True False Wnt is a regulatory factor that regulate myogenic stem cell proliferation? True Falsearrow_forward
- Gene dosage—the number of copies of a gene that areactively being expressed—is important to proper development. Identify and describe two processes that establish the proper dosage of certain genes.arrow_forwardExplain how morphogens and cell-to-cell contacts conveypositional information.arrow_forwardIn which tissue(s) is the mRNA and protein highly expressed in? 1. Go to: https://www.proteinatlas.org/2. Type the name of your protein in the search bar. Click "Search"3. Click on the gene name of your protein4. Click on the "Tissue" icon5. Scroll down to the graphs showing Protein and mRNA expression.6. Search for the tissue type that shows high expression in both the protein and mRNA graphs. Kidney Placenta Adipose tissue Stomach Ovary *Can be more than one answer*arrow_forward
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