Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 19.1, Problem 2COMQ
A down promoter mutation causes the promoter of a gene to be _______ like the consensus sequence and _________ transcription.
a. less, stimulates
b. more, stimulates
c. less, inhibits
d. more, inhibits
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Students have asked these similar questions
A nonsense mutation
Select one:
a.
results in a larger protein being produced from the mutated gene
b. will lead to premature termination of translation
c.
is the same as a silent mutation
d. will lead to the premature termination of transcription
A transcription factor (protein - orange/green) is bound to a promoter of a gene (DNA - blue) it regulates. What changes would result in the gene not being expressed?
A. Mutations in the DNA sequence where the TF is bound
B. Mutations in the DNA binding domain of the TF
C. Mutations in the 3’UTR (untranslated region) of this gene
A and B only
B and C only
A, B, and C
A down promoter mutation causes the promoter of a gene to be_______ like the consensus sequence and _________ transcription.a. less, stimulatesb. more, stimulatesc. less, inhibitsd. more, inhibits
Chapter 19 Solutions
Genetics: Analysis and Principles
Ch. 19.1 - 1. A mutation changes a codon that specifies...Ch. 19.1 - A down promoter mutation causes the promoter of a...Ch. 19.1 - 3. A mutation in one gene that reverses the...Ch. 19.1 - Which of the following is an example of a somatic...Ch. 19.2 - Prob. 1COMQCh. 19.3 - Which of the following is not an example of a...Ch. 19.3 - A point mutation could be caused by a....Ch. 19.3 - One way that TNRE may occur involves the formation...Ch. 19.4 - Nitrous acid replaces amino groups with keto...Ch. 19.4 - Prob. 2COMQ
Ch. 19.4 - Prob. 3COMQCh. 19.5 - The function of photolyase is to repair a....Ch. 19.5 - Which of the following DNA repair systems may...Ch. 19.5 - 3. In nucleotide excision repair in E. coli, the...Ch. 19.5 - Prob. 4COMQCh. 19.5 - An advantage of translesion-replicating...Ch. 19 - Is each of the following mutations a transition,...Ch. 19 - Prob. 2CONQCh. 19 - What does a suppressor mutation suppress? What is...Ch. 19 - Prob. 4CONQCh. 19 - X-rays strike a chromosome in a living cell and...Ch. 19 - Prob. 6CONQCh. 19 - Prob. 7CONQCh. 19 - 8. A point mutation occurs in the middle of the...Ch. 19 - Prob. 9CONQCh. 19 - Prob. 10CONQCh. 19 - 11. Is a random mutation more likely to be...Ch. 19 - 12. Which of the following mutations could be...Ch. 19 - Prob. 13CONQCh. 19 - Discuss the consequences of a germ-line versus a...Ch. 19 - Prob. 15CONQCh. 19 - Explain how a mutagen can interfere with DNA...Ch. 19 - What type of mutation (transition, transversion,...Ch. 19 - Explain what happens to the sequence of DNA during...Ch. 19 - Distinguish between spontaneous and induced...Ch. 19 - Prob. 20CONQCh. 19 - Prob. 21CONQCh. 19 - Prob. 22CONQCh. 19 - Trinucleotide repeat expansions (TNREs) are...Ch. 19 - 24. With regard to TNRE, what is meant by the term...Ch. 19 - 25. What is the difference between the mutation...Ch. 19 - Achondroplasia is a rare form of dwarfism. It is...Ch. 19 - Prob. 27CONQCh. 19 - In the treatment of cancer, the basis for many...Ch. 19 - Prob. 29CONQCh. 19 - 30. Which of the following examples is likely to...Ch. 19 - Prob. 31CONQCh. 19 - Prob. 32CONQCh. 19 - Prob. 33CONQCh. 19 - With regard to the repair of double-strand breaks,...Ch. 19 - Prob. 35CONQCh. 19 - Prob. 36CONQCh. 19 - 37. Three common ways to repair changes in DNA...Ch. 19 - Prob. 38CONQCh. 19 - Prob. 39CONQCh. 19 - Explain how the technique of replica plating...Ch. 19 - 2. Outline how you would use the technique of...Ch. 19 - 3. From an experimental point of view, is it...Ch. 19 - Prob. 4EQCh. 19 - Prob. 5EQCh. 19 - 6. Richard Boyce and Paul Howard-Flanders...Ch. 19 - In E. coli, a variety of mutator strains have been...Ch. 19 - 2. Discuss the times in a person’s life when it is...Ch. 19 - A large amount of research is aimed at studying...
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- The binding of ________ is required for transcription to start. a. a protein b. DNA polymerase c. RNA polymerase d. a transcription factorarrow_forwardWhich of these is used in the transcription of all genes? Choose all correct answers. A. Core promoter B. Proximal promoter C. Distal promoter D. General Transcription Factors E. Regulatory Transcription Factorsarrow_forwardA repressor is a __________ that _________ transcription. a. small effector molecule, inhibits b. small effector molecule, enhances c. regulatory protein, inhibits d. regulatory protein, enhancesarrow_forward
- Which of the following is not true regarding gene regulation that involves DNA bending? a. The precise distance between the regulatory sequence and the promoter is important. b. Effect can be to repress transcription c. Effect can be to activation transcription d. Regulated genes can be thousands of base pairs away from the regulatory sitesarrow_forwardProteins that influence RNA synthesis by binding directly to DNA are called_____ . a. promoters c. operators b. transcription factors d. enhancersarrow_forwardmRNA is the type of RNA that gets translated. A. True b. False Transcription forms new strands 3'-->5’. a. True b. Falsearrow_forward
- Mutations in the promoter region of the β-globin gene indicate that some areas are more sensitive than others. When mutations occur in consensus sequences (modular elements such as GC box, CAAT box, TATA box), transcription usually A. increases b. stays about the same c. decreasesarrow_forwardImagine that mutations occurred in one of the inverted repeat sequences within the rho-independent terminator sequence of a bacterium. What would likely be the consequence of this mutation? Select one: a. Transcription may not be initiated at all. b. Transcription may end prematurely. c. Transcription may be delayed. d. The rho protein won't be able to bind and transcription may not be terminate. e. Transcription may not be terminated and result in much longer RNA.arrow_forwardPromoters always contain a ________. a. TATA box b. GC-rich box c. ATAT sequencearrow_forward
- The transcription factors would recognize and bind to nucleotides between the positions _____________________________. Group of answer choices A. +1 to +55 B. -1 to -22 C. -16 to -22 D. +1 to +25arrow_forwardWhich statement/s is/are TRUE about transcription?A. During transcription, DNA polymerase binds to RNA and separates the DNA strands.B. RNA polymerase uses one strand of DNA as a template to assemble nucleotides into a strand of RNA.C. RNA polymerase binds only to DNA promoters, which have specific base sequences.D. Promoters are signals in RNA that indicate to RNA polymerase where to begin transcription.E. Transcription occurs in the 3’ to 5’ direction with respect to the growing mRNA strand.arrow_forwardA scientist is interested in producing flowers with a darker red color. To do this, the scientist alters the promoter of the gene to make it more active. This results in increased transcription and increased red pigments. The scientist then alters the promoter to make it even more active. This results in white flowers with no red pigment. Genetic research showed an increase in the siRNA in the cell. What did the siRNA do to the mRNA? A. The siRNA caused the mRNA to be broken down. B. The siRNA caused alternative splicing of the mRNA. C. The siRNA caused increased methylation of the mRNA. D. The siRNA caused the ribosome to no longer recognize this mRNA.arrow_forward
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