Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 17, Problem 6EQ
Summary Introduction

To review:

miRNA (micro ribonucleic acid) replacement therapy and three different examples of its approaches.

Introduction:

miRNAsare, as the name suggests, short sequences of RNA which do not code for proteins. Instead, they are involved in regulation of gene expression. They bind to mRNAs (messenger RNAs) through base complementarity, thus, decreasing translation of said mRNA into a functional protein.

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Compare and contrast anti-miRNA oligonucleotides, locked nucleicacids (LNAs), and antagomirs, which may eventually be used to treat certain forms of cancer.
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What are the differences between miRNA and siRNA? (Select all that apply.) OmiRNAs carry the genetic information from the DNA in the nucleus directly to the cytoplasm, and siRNAs are involved in the degradation of specific mRNA molecules. miRNAs are from 22 to 30 bases long, and siRNAs are 22 bases long. O miRNAs carry the genetic information from the DNA in the nucleus directly to the cytoplasm, and siRNAs help with the processing of the initial mRNA transcribed from DNA into a mature form. miRNAs prevent translation of certain mRNAs, and siRNAs are involved in the degradation of specific mRNA molecules. miRNAs are 20 to 22 bases long, and siRNAs are from 20 to 30 bases long.

Chapter 17 Solutions

Genetics: Analysis and Principles

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