Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 17.1, Problem 2COMQ
When an ncRNA functions as a decoy, it
a. contains binding sites for many different proteins, thereby promoting the formation of a large complex.
b. recognizes other ncRNAs and sequesters them, thereby preventing them from working.
c. can alter its conformation, allowing it to switch between active and inactivate conformations.
d. may physically prevent or block a cellular process from happening.
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Alternative RNA splicing
a. is a mechanism for increasing the rate of transcription.
b. can allow the production of proteins of different sizes from a gene.
C. can allow the production of similar proteins from different RNAS.
d. increases the rate of transcription.
e. is due to the presence or absence of particular snRNAs.
Changes in a cell that affect micro RNAs lead to cancer because miRNAs...
a. help a cell to maintain a tight control on protein levels in a cell.
b. decrease the level of a specific protein.
c. increase the level of a specific protein.
d. prevent the Warburg effect.
An ncRNA may have the following functions: scaffold, guide, alterer of protein function or stability, ribozyme, blocker, and/or decoy. Which of these functions are mediated by each type of ncRNA listed next? Note: A singlencRNA may have more than one function.
A. tRNAB. rRNAC. SRP RNAD. piRNA
Chapter 17 Solutions
Genetics: Analysis and Principles
Ch. 17.1 - Which of the following can bind to ncRNAs? a. DNA...Ch. 17.1 - 2. When an ncRNA functions as a decoy, it
a....Ch. 17.1 - Prob. 3COMQCh. 17.2 - 1. Which of the following functions does HOTAIR...Ch. 17.3 - 1. The process of RNA interference may lead to
a....Ch. 17.3 - 2. In catalyzing the methylation or...Ch. 17.4 - 1. Which of the following is a function of SRP?...Ch. 17.5 - 1. Which of the following components are needed...Ch. 17.5 - 2. In the CRISPR-Cas system, what does the...Ch. 17.5 - Which of the following is a function of the...
Ch. 17.6 - Prob. 1COMQCh. 17.6 - Let's suppose that the overexpression of a...Ch. 17 - 1. List and briefly describe four types of...Ch. 17 - 2. An ncRNA may have the following functions:...Ch. 17 - 3. What is meant by the term RNA world? Describe...Ch. 17 - Explain how HOTAIR plays a role in the...Ch. 17 - What is the phenomenon of RNA interference (RNAi)?...Ch. 17 - With regard to RNAi, what are three possible...Ch. 17 - 7. What is the difference between an miRNA and an...Ch. 17 - Together with a specific set of proteins, snoRNAs...Ch. 17 - Describe the structure of SRP in eukaryotes, and...Ch. 17 - Look at Figure 17.6 and predict what would happen...Ch. 17 - Compare and contrast the roles of crRNA and...Ch. 17 - In the CRISPR-Cas system, does the tracrRNA act as...Ch. 17 - Prob. 13CONQCh. 17 - Outline the steps that occur when piRISCs silence...Ch. 17 - List five types of cancer in which ncRNAs can be...Ch. 17 - Prob. 16CONQCh. 17 - A protein called trypsin, which plays a role in...Ch. 17 - Prob. 2EQCh. 17 - Prob. 3EQCh. 17 - As described in Chapter 21, the CRISPR-Cas system...Ch. 17 - Prob. 5EQCh. 17 - Prob. 6EQCh. 17 - Prob. 1QSDCCh. 17 - Go to the PubMed website and do a search using the...
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- Complete the following sentence: Transcription of DNA by RNA polymerase II synthesises microRNA precursor transcript in: A. either the 3′ to 5′ direction or the 5′ to 3′ direction depending on the orientation of the gene B. a discontinuous fashion. C. the 3′ to 5′ direction. D. both the 3′ to 5′ direction and the 5′ to 3′ direction simultaneously E. the 5′ to 3′ direction.arrow_forwardAn ncRNA may have the following functions: scaffold, guide,alterer of protein function or stability, ribozyme, blocker, and/ordecoy. Which of those functions is/are mediated by each of thencRNAs listed next? (Note: A single ncRNA may have more thanone function.) A. HOTAIRB. RNA of RNasePC. microRNAD. crRNAarrow_forwardDefine the following terms: a. promoter b. consensus sequence c. operon d. chromatin-remodeling complex e. general transcription factorsarrow_forward
- Which of the following is an intron and intergenic coded long transcripts, processed into stem and loop structures that may bind specifically or otherwise? a. spliceosome RNA b. LncRNA c. miRNA d. piRNA e. siRNAarrow_forwardDifferential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single genearrow_forwardArrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forward
- Abnormalities in the expression of ncRNAs are associated witha. many forms of cancer.b. neurological disorders.c. cardiovascular diseases.d. all of the above.arrow_forwardWhich of the following is NOT TRUE about Eukaryotic Transcription: A. Occurs in the cytoplasm B. Pol II has 12 subunits C. Pol III transcribes tRNA genes D. It’s controlled by Cis-acting sequences E. Leads to specialization of cell functionarrow_forwardDefine the following terms:a. cistronb. operonc. miRNAd. siRNAe. snoRNAarrow_forward
- Which of the following is an RNA processing event that increases the number of potential polypeptides that can be encoded by a single gene. a. transcription b. alternative splicing c. alternative transcription d. polyadenylationarrow_forwardDefine the following terms: a. noncoding RNA b. miRNA c. siRNA d. snoRNA e. lncRNAarrow_forwardTwo different types of gene regulatory elements are DNA sequence and protein-based. Which of the following describes them, respectively? a. one blocks translation, the other blocks transcription b. The first is an aporepressor, the second is a promoter c. The first is an enhancer, the second is a repressor d. The first is a activator, the second is a an attenuator e. one is an activist, the other is a protestorarrow_forward
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