Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 17, Problem 12P
What type or types of inheritance are consistent with the following pedigree?
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The following pedigree shows what type of inheritance?
In the following pedigree, is the disorder’s mode of inheritanceautosomal dominant, autosomal recessive, or X-linked recessive?Explain your reasoning.
What is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.
Chapter 17 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 17 - 17.1 Reciprocal crosses of experimental animals or...Ch. 17 - 17.2 How are some of the characteristics of the...Ch. 17 - 17.3 The human mitochondrial genome encodes...Ch. 17 - What is the evidence that transfer of DNA from the...Ch. 17 - Draw a graph depicting the relative amounts of...Ch. 17 - Prob. 6PCh. 17 - 17.7 What is the evidence that the ancient...Ch. 17 - 17.8 Outline the steps required for a gene...Ch. 17 - 17.9 Consider the phylogenetic tree presented in...Ch. 17 - You are a genetic counselor, and several members...
Ch. 17 - A mutation in Arabidopsis immutans results in the...Ch. 17 - What type or types of inheritance are consistent...Ch. 17 - You have isolated (1) a streptomycin-resistant...Ch. 17 - You have isolated two petite mutants, pet1 and...Ch. 17 - 17.15 Consider this human pedigree for a vision...Ch. 17 - A 50- year - old man has been diagnosed with MELAS...Ch. 17 - 17.17 The first person in a family to exhibit...Ch. 17 - Prob. 18PCh. 17 - 17.19 What is the most likely mode of inheritance...Ch. 17 - 17.20 In , the Russian Tsar Nicholaswas deposed,...Ch. 17 - 17.21 The dodo bird (Raphus cucullatus) lived on...Ch. 17 - Cytoplasmic male sterility (CMS) in plants has...Ch. 17 - 17.23 Wolves and coyotes can interbreed in...Ch. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Most large protein complexes in mitochondria and...Ch. 17 - As described in this chapter, mothers will pass on...
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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forwardWhich mode of inheritance is suggested by the following pedigree? Based on this hypothesis, and assuming that the trait is rare and has complete penetrance, what are the possible genotypes of all individuals in this pedigree?arrow_forwardIn each of the following pedigrees (C, D) by inspection, determine the mode of inheritance involved. Indicate the possible genotypes of all individuals in all the pedigrees.arrow_forward
- What is the one most probable mode of inheritance for this pedigree and why?arrow_forwardFor each of the following modes of inheritance, describe the features that will be exhibited in a pedigree in which the trait is present: autosomal recessive, autosomal dominant, X-linked recessive, X-linked dominant, and Y-linked inheritance.arrow_forwardWhy is “threshold of liability” an important consideration in multifactorial inheritance?arrow_forward
- What is the partern of inheritance in pedigree a and b? Explain why.arrow_forward—Hereditary canine spinal muscular atrophy (HCSMA) is a motor neuron disease in Brittany Spaniels. Breeding studuies within a kindred of more than 125 dogs (Brittany spaniel and beagle-Brittany outcrosses) have established an autosomal dominant inheritance for HCSMA. Which of the following genotypes would cause the dog to NOT HAVE HCSMA? Hh HH Hh A and C B and C– —(see question above for genotype) is a spaniel who is homozygous recessive for the HCSMA trait had a puppy with a spaniel who was heterozygous for this trait, what is the probability that the puppy would be normal? 0% 25% 50% 75% 100%arrow_forwardThe following pedigree illustrates the inheritance of ringed hair, a condition in which each hair is differentiated into light and dark zones. What mode or modes of inheritance are possible for the ringed-hair trait in this family?arrow_forward
- Identify the pattern of inheritance shown in each of the following pedigrees. If the pedigree illustrates more than one (1) mode of inheritance, just choose one. Afterwards, determine the genotype and phenotype of the first 5 individuals in each pedigreearrow_forwardAcatalasia is caused by a rare autosomal recessive gene. In heterozygous condition catalase activity is decreased slightly. A woman with a normal catalase activity have a husband with low catalase activity. What is the probability of children birth without anomaly in the family, if grandparents from both sides have reduced activity of catalase? Diagram the cross and mention the genotypes of all individuals in the family?arrow_forwardPropose the most likely mode of inheritance (autosomal dominant, autosomal recessive, or X-linked recessive) for the following pedigrees. Affected individuals are shown with filled (black)symbols.arrow_forward
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