Hereditary canine spinal muscular atrophy (HCSMA) is a motor neuron disease in Brittany Spaniels. Breeding studuies within a kindred of more than 125 dogs (Brittany spaniel and beagle-Brittany outcrosses) have established an autosomal dominant inheritance for HCSMA. Which of the following genotypes would cause the dog to NOT HAVE HCSMA? Hh HH Hh A and C B and C–   —(see question above for genotype) is a spaniel who is homozygous recessive for the HCSMA trait had a puppy with a spaniel who was heterozygous for this trait, what is the probability that the puppy would be normal? 0% 25% 50% 75% 100%

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.