Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 11, Problem 6RQ
Summary Introduction
To determine: In the given pedigree analysis, whether the individuals showing the trait are homozygous or heterozygous.
Introduction: The inheritance of traits shows patterns used for the prediction of the reappearance of the traits in the offspring. The patterns of inheritance are classified based on their relation to the autosomes or sex chromosomes and with dominant and recessive inheritance patterns.
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For this pedigree, give the most likely mode of inheritance, assuming that the trait is rare.
For the pedigree, what is the probability that III-4 and III-5 will have a boy AND he will be affected?
In pedigrees, individuals are usually specified by using a Roman numeral for their generation in the chart and an Arabic number for their position (reading left to right) within that generation. If we use the letter c for the allele that causes cystic fibrosis, what are the genotypes of individuals III-3 and III-4 (the third and fourth individuals shown in generation III) in the pedigree that shows this disease?
The pedigree below shows a family with a history of an autosomal recessive genetic
disease with one individual's genotype indicated (G denotes the normal allele and g
denotes the disease-causing allele).
*
O 0
O 1/8
1/4
O 1/16
Individual 1's father is known to be heterozygous (*) and his mother is known to be
homozygous dominant. Other individuals in the pedigree may be carriers, but are not
marked. The question mark (?) indicates that you do not yet know anything about this
individual's phenotype with regard to the disease.
Part 1
What is the probability that individuals 1 and 2 will have a child (5) who is a male with the
disease (the child is unborn and the sex is not yet known)?
O 1/4
1
O 1/6
5
1/8
2
01/12
gg
3
Part 2
What is the probability that the daughter (female)(6) that individual 3 and 4 just had will have the
disease?
6
Chapter 11 Solutions
Biology
Ch. 11.1 - describe the relationships among chromosomes,...Ch. 11.1 - Prob. 2CYLCh. 11.2 - distinguish between self-fertilization and...Ch. 11.2 - Prob. 2CYLCh. 11.3 - Prob. 1TCCh. 11.3 - Prob. 1CSCCh. 11.3 - describe the pattern of inheritance of a trait...Ch. 11.3 - Prob. 2CYLCh. 11.3 - Prob. 3CYLCh. 11.4 - Can the genotype of a plant grown from a smooth,...
Ch. 11.4 - Prob. 2TCCh. 11.4 - Prob. 1CYLCh. 11.4 - Prob. 2CYLCh. 11.4 - Prob. 3CYLCh. 11.5 - Prob. 1TCCh. 11.5 - Prob. 1CSCCh. 11.5 - Prob. 1HYEWCh. 11.5 - Prob. 1CYLCh. 11.5 - Prob. 2CYLCh. 11.6 - describe how the patterns of inheritance differ...Ch. 11.7 - If a color-deficient woman and a man with normal...Ch. 11.7 - Prob. 1CYLCh. 11.7 - explain why most sex-linked traits are controlled...Ch. 11.7 - describe the pattern of inheritance of sex-linked...Ch. 11.8 - Prob. 1TCCh. 11.8 - use pedigrees to determine the pattern of...Ch. 11.8 - Prob. 2CYLCh. 11.8 - Prob. 3CYLCh. 11.8 - Prob. 2TCCh. 11.8 - Prob. 1CTCh. 11 - Prob. 1MCCh. 11 - Prob. 2MCCh. 11 - Independent assortment means that a. two genes on...Ch. 11 - Prob. 4MCCh. 11 - Prob. 5MCCh. 11 - An organism is described as Rr, with red coloring....Ch. 11 - Prob. 2FIBCh. 11 - Prob. 3FIBCh. 11 - Genes that are present on one sex chromosome but...Ch. 11 - Prob. 5FIBCh. 11 - Define the following terms: gene, allele,...Ch. 11 - Prob. 2RQCh. 11 - Prob. 3RQCh. 11 - Prob. 4RQCh. 11 - Prob. 5RQCh. 11 - Prob. 6RQCh. 11 - Prob. 1ACCh. 11 - Prob. 2ACCh. 11 - In certain cattle, hair color can be red...Ch. 11 - In the edible pea, tall (T) is dominant to short...Ch. 11 - Prob. 3GPCh. 11 - Prob. 4GPCh. 11 - Prob. 5GP
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- *Cystic fibrosis is a rare autosomal recessive condition. phenotypically normal man whose father had cystic fibrosis marries a phenotypically normal woman from outside the family.² a) Draw the pedigree as far as described. b) If the frequency of heterozygotes in the general population is 1/50, what is the probability that the couple's first child will have cystic fibrosis? c) If the first child does have cystic fibrosis, what is the probability that the second child will be normal?arrow_forwardThe following family pedigree shows individuals afflicted with a metabolic disease. Suppose the male (b) and the female (c) have 2 girls and 2 boys, indicate directly on the pedigree the symbols for these children that would be most consistent with the mode of inheritance observations in the pedigree? II II a b d e IVarrow_forwardThis is a pedigree for a dominant trait caused by gene A in humans. Shaded symbols show individuals affected with the trait; non-shaded individuals are normal (aa). Among the progeny arising from the marriage of individual III-1, what proportion would be expected to show the trait? Among the progeny arising from the marriage of individual III-6, what proportion would be expected to show the trait?arrow_forward
- The accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information. 1) What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AAAA and two of them are AaAa? (Hint: Consider all possible orders of genotypes.) Express your answer to two decimal places.arrow_forwardThe three genes X, Y, and Z are linked on an autosomal chromosome in humans (X to Y is 15 cM, and Y to Z is 18 cM). If an individual that is heterozygous at all three loci (XYZ/xyz) has children with an individual that is homozygous recessive at all three loci (xyz/xyz), what is the probability that they will have a child that is phenotypically identical to either parent (X-Y-Z- or xxyyzz)? Assume there is no genetic interference to double crossover events at this site.arrow_forwardDefine the pedigree symbol(s) associated with each of the following individuals. Please be as specific as possible. Be sure to indicate WHOSE pedigree symbols you are defining. (i) II-1 and II-3 (ii) II-5 (iii) II-9-10 (iv) II-11 (v) IV-14 and IV-15 (vi) IV-18arrow_forward
- Given the following pedigree: Is the trait autosomal or sex-linked? Is the trait dominant or recessive? Based only on the information given, what is the probability that I-2 is heterozygous? Give the genotypes of individuals II-3, II-4. What is the probability that individual III-1 is purebreeding?arrow_forwardFor the following cross, show the P generation Genotypes and the Phenotypic ratio that would be seen in the F1 and F2. Remember, to produce the F2 generation you want to cross Heterozygotes from the F1. d) Genes 1 and 2 exhibit Epistasis (9:6:1) and Gene 3 is an Autosomal Dominant. In the P generation, the Male is Homozygous Recessive for the Genes showing Epistasis. Use E1, E2 and E3 to represent the Phenotypes shown by Epistasis. Report your results in the following format: P = aabb x AABB, F1 = 100%AaBb (Phenotype), and %3! F2 = 9/16 A_B_ (Phenotype), 3/16 aaB (Phenotype), 3/16 A_bb (Phenotype), 1/16 aabb (Phenotype)arrow_forwardIn each of the following pedigrees (A, B) by inspection, determine the mode of inheritance involved. Indicate the possible genotypes of all individuals in all the pedigrees.arrow_forward
- In the below pedigree, what is the probability that the individual in generation V (marked as a "?") will have the mutant phenotype? (Assume that the mutant phenotype manifests during childhood and individual III-6 is homozygous). Enter your answer as a fraction without spaces (e.g. 9/16)arrow_forwardThe individuals with a certain disease are shown in this pedigree. The disease is caused by an autosomal recessive allele, q. Give the genotype of the following individuals: (a) III-1 (the girl at lower left corner) (b) II-1 (the girl’s mother) (c) II-2 (the girl’s father)arrow_forwardTwo unlinked genes, A and B, encode very similar enzymes involved in the production of purple flower pigments in a particular plant species. Recessive, non-functional alleles a and b are available. If the A and B genes are functionally redundant, so a single functional copy of either gene is sufficient for purple pigmentation, what proportion of the progeny of a cross between AaBb double heterozygotes is expected to have white flowers? 1/8 O 1/4 O 1/16 O 1/32arrow_forward
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