Chapter 11.8, Problem 1CT

Summary Introduction

To explain: Whether the genetic modification of defective alleles of sperm and eggs should be permitted or not.

Introduction: “Marfan syndrome” is caused due to mutation in the gene FBN1 that produces a protein called Fibrillin-1. This protein forms microfibrils inside the cells, which support the connective tissues. The defect in this protein causes a lack of strength in the connective tissues of the human body. It is inherited in the form of the autosomal dominant trait.