Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 10, Problem 1QSDC
Bacterial and eukaryotic chromosomes are very compact. Discuss the advantages and disadvantages of a compact chromosomal structure.
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Describe the structure of nucleosome
( please keep it short as much as you can ) .
A major difference between prokaryotes and eukaryotes is the presence of a nucleus. What advantages and disadvantages may occur with having a cell’s genome packaged in a nucleus?
A previously undiscovered single-cell organism was found living at a great depth on the ocean floor. Its nucleus contained only a single linear chromosome with 7 x 106 nucleotide pairs of DNA coalesced with three types of histone-like proteins. Consider the following questions:
Question: The analysis of individual nucleosomes reveals that each unit contained one copy of each protein and that the shortlinker DNA contained no protein bound to it. If the entirechromosome consists of nucleosomes (discounting any linkerDNA), how many are there, and how many total proteins areneeded to form them?
Chapter 10 Solutions
Genetics: Analysis and Principles
Ch. 10.1 - 1. A bacterial chromosome typically contains
a. a...Ch. 10.2 - Mechanisms that make the bacterial chromosome more...Ch. 10.2 - 2. Negative supercoiling may enhance activities...Ch. 10.2 - 3. DNA gyrase
a. promotes negative supercoiling....Ch. 10.3 - 1. The chromosomes of eukaryotes typically contain...Ch. 10.4 - Which of the following is an example of a...Ch. 10.5 - What are the components of a single nucleosome? a....Ch. 10.5 - 2. In Noll’s experiment to test the...Ch. 10.5 - Prob. 3COMQCh. 10.5 - Prob. 4COMQ
Ch. 10.6 - Prob. 1COMQCh. 10.6 - 2. The role of cohesin is to
a. make chromosomes...Ch. 10 - Prob. 1CONQCh. 10 - Prob. 2CONQCh. 10 - 3. Describe the mechanisms by which bacterial DNA...Ch. 10 - Why is DNA supercoiling called supercoiling rather...Ch. 10 - Prob. 5CONQCh. 10 - Prob. 6CONQCh. 10 - Prob. 7CONQCh. 10 - Prob. 8CONQCh. 10 - Prob. 9CONQCh. 10 - 10. What is the function of a centromere? At what...Ch. 10 - Prob. 11CONQCh. 10 - 12. Describe the structures of a nucleosome and a...Ch. 10 - Beginning with the G1 phase of the cell cycle,...Ch. 10 - Draw a picture depicting the binding between the...Ch. 10 - 15. Compare heterochromatin and euchromatin. What...Ch. 10 - 16. Compare the structure and cell localization of...Ch. 10 - 17. What types of genetic activities occur during...Ch. 10 - Lets assume the linker region of DNA averages 54bp...Ch. 10 - 19. In Figure 10.12, what are we looking at in...Ch. 10 - 20. What are the roles of the core histone...Ch. 10 - A typical eukaryotic chromosome found in humans...Ch. 10 - Which of the following terms should not be used to...Ch. 10 - Discuss the differences between the compaction...Ch. 10 - 24. What is an SMC complex? Describe two...Ch. 10 - Two circular DNA molecules, which we can call...Ch. 10 - 2. Let’s suppose you have isolated DNA from a cell...Ch. 10 - 3. We seem to know more about the structure of...Ch. 10 - In Nolls experiment of Figure 10.11, explain where...Ch. 10 - When chromatin is treated with a salt solution of...Ch. 10 - 6. Let’s suppose you have isolated chromatin from...Ch. 10 - If you were given a sample of chromosomal DNA and...Ch. 10 - Consider how histone proteins bind to DNA and then...Ch. 10 - In Chapter 23, the technique of fluorescence in...Ch. 10 - Bacterial and eukaryotic chromosomes are very...Ch. 10 - The prevalence of highly repetitive sequences...Ch. 10 - Discuss and make a list of the similarities and...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- All of the following statements regarding nucleosomes are true EXCEPT A each bead-like structure contains 8 molecules of histones H1, H2A, H2B, H3 and H4 the bead like structures are made up of core histones wrapped around by the DNA strands the histone proteins in the nucleosomes contain positively charged amino acids that interact with the negatively charged DNA D the bead like structures are linked to each other by the DNA chainarrow_forwardConsider the following DNA molecule (shown in the picture) and assume this is the DNA sequence of the entire chromosomes. list the amino acid sequences of the possible protein or proteins that could be produced from this DNA sequence what would be the DNA sequence of a sister chromatid generated from this chromosome sequence? (specify the 5' nd 3' ends)arrow_forwardIf the DNA of chromosome 1 is fully extended, it will exceed the diameter of the nucleus of a cell by about 15,000 times. Therefore, discuss how DNA is packaged into the cell.arrow_forward
- Chromosomal Basis of Heredity Eukaryotic chromosomes are thousands of times longer than a typical cell. Explain how chromosomes can fit inside a eukaryotic nucleus. How are chromosomes in eukaryotic cells packaged? Chromosome abnormalities can be structural or numerical. Enumerate at least 3 examples of each, giving the numerical or structural changes in the chromosomes.arrow_forwardThe analysis of individual nucleosomes reveals that each unit contained one copy of each protein and that the short linker DNA contained no protein bound to it. If the entire chromosome consists of nucleosomes (discounting any linker DNA), how many are there, and how many total proteins are needed to form them?arrow_forwardDiscuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forward
- The haploid human genome consists of approximately 3.2 × 109 bp (or 6.4 × 109 bp per diploid genome). Assuming that DNA is B-DNA, calculate the total length of a single cell’s DNA.arrow_forwardThe DNA molecules in eukaryotes including humans are negatively supercoiled while that in prokaryotes and viruses is positively supercoiled. (true/false, explain)arrow_forwardBriefly discuss the pros and cons of having a nucleoid (as bacteria do) versus a double nuclear membrane surrounding the DNA (as in eukaryotes). List and explain three reasons why DNA replication is very accurate.arrow_forward
- Kree DNA has histone like proteins that wrap up in nucleosomes. The Kree have a core DNA length of 255 bp and a linker DNA of 45 bp. The Kree genome is made up of approximately 6x108 base pairs of DNA. Determine the number of nucleosomes in each nucleus.arrow_forwardWe seem to know more about the structure of eukaryotic chromosomal DNA than bacterial DNA. Discuss why you think this is so,and list several experimental procedures that have yielded important information concerning the compaction of eukaryoticchromatinarrow_forwardWhy evenly spaced sequence in chromatogram is an indication of a good DNA chromatogram?arrow_forward
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