Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 8.3, Problem 2COMQ
Summary Introduction
Introduction:
Duplication is a type of gene mutation which causes a certain section of the chromosome to be repeated. A copy of a gene is repeated and this causes a change in the overall structure of the chromosome. They are caused due to non-allelic homologous recombination.
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With regard to gene duplications, which of the following statement(s) is/are correct?a. Gene duplications may be caused by nonallelic homologousrecombination.b. Large gene duplications are more likely to be harmful thansmaller ones.c. Gene duplications are responsible for creating gene familiesthat encode proteins with similar and specialized functions.d. All of the above statements are correct.
You are studying four linked genes located on chromosome 2 in the fruit fly Drosophila
melanogaster: adp (which contributes to obesity), b (which contributes to body color), pr (which
contributes to metabolism), and vg (which contributes to wing formation). A series of crosses
between pair-wise combinations of these mutations yielded the following recombination frequencies
between the indicated loci:
pr and adp 9%
adp and b 6%
pr and b 3%
vg and b 10%
vg and pr 7%
What is the genetic distance in map units (cM) between the adp and vg loci?
16
9
6
4
Ensure answers are clearly labelled a) & b).
a) Consider the following pedigree. The solid symbols represent affected individuals. Which of the following is / are possible genotypes
for II-2 with respect to this disease? Please type 1 - 4, and indicate yes or no only for each.
II
III
1. xAxa
2. xaxa
3. Aa
4. AA2
b) Genes A, B and C are on the same chromosome linked in cis (coupling) conformation. A'is 16 cM from B, and B is 22 cM from C. The
distance between A and C is 38 cM. The coefficient of coincidence is 0.55 for a trihybrid test cross. How many individuals with the
genotype AabbCc do you expect to see among the offspring of the cross if 1000 offspring are obtained? Please show your calculations
and round your answer off to the nearest whole number.
Chapter 8 Solutions
Genetics: Analysis and Principles
Ch. 8.1 - 1. A chromosome that is metacentric has its...Ch. 8.1 - Staining eukaryotic chromosomes is useful because...Ch. 8.2 - Prob. 1COMQCh. 8.3 - Which of the following statements is correct? a....Ch. 8.3 - Prob. 2COMQCh. 8.4 - 1. A paracentric inversion
a. includes the...Ch. 8.4 - Due to crossing over within an inversion loop, a...Ch. 8.4 - 3. A mechanism that may cause a translocation is...Ch. 8.5 - 1. Humans have 23 chromosomes per set. A person...Ch. 8.6 - Prob. 1COMQ
Ch. 8.6 - Prob. 2COMQCh. 8.7 - The term endopolyploidy refers to the phenomenon...Ch. 8.7 - 2. In agriculture, an advantage of triploidy in...Ch. 8.8 - Prob. 1COMQCh. 8.8 - The somatic cells of an allotetraploid contain a....Ch. 8 - 1. Which changes in chromosome structure cause a...Ch. 8 - Prob. 2CONQCh. 8 - 3. How does a chromosomal duplication occur?
Ch. 8 - 4. What is a gene family? How are gene families...Ch. 8 - Prob. 5CONQCh. 8 - Two chromosomes have the following orders for...Ch. 8 - An inversion heterozygote has the following...Ch. 8 - Prob. 8CONQCh. 8 - Explain why inversions and reciprocal...Ch. 8 - 10. An individual has the following reciprocal...Ch. 8 - A phenotypically normal individual has the...Ch. 8 - 12. Two phenotypically normal parents produce a...Ch. 8 - With regard to the segregation of centromeres, why...Ch. 8 - Prob. 14CONQCh. 8 - Prob. 15CONQCh. 8 - 16. A phenotypically abnormal individual has a...Ch. 8 - 17. A diploid fruit fly has eight chromosomes. How...Ch. 8 - Prob. 18CONQCh. 8 - Prob. 19CONQCh. 8 - 20. Aneuploidy is typically detrimental, whereas...Ch. 8 - 21. Explain how aneuploidy, deletions, and...Ch. 8 - Prob. 22CONQCh. 8 - 23. A cytogeneticist has collected tissue samples...Ch. 8 - Prob. 24CONQCh. 8 - A zookeeper has collected a male and a female...Ch. 8 - Prob. 26CONQCh. 8 - 27. What is mosaicism? How is it produced?
Ch. 8 - 28. Explain how polytene chromosomes of Drosophila...Ch. 8 - 29. Describe some of the advantages of polyploid...Ch. 8 - 30. While conducting field studies on a chain of...Ch. 8 - Prob. 31CONQCh. 8 - Which of the following terms should not be used to...Ch. 8 - Prob. 33CONQCh. 8 - Prob. 34CONQCh. 8 - A triploid plant has 18 chromosomes (i.e., 6...Ch. 8 - Prob. 36CONQCh. 8 - Prob. 37CONQCh. 8 - 38. A woman who is heterozygous, Bb, has brown...Ch. 8 - 39. What is an allodiploid? What factor determines...Ch. 8 - Prob. 40CONQCh. 8 - 41. Table 8.1 shows that Turner syndrome occurs...Ch. 8 - 42. Male honeybees, which are haploid, produce...Ch. 8 - Prob. 1EQCh. 8 - Prob. 2EQCh. 8 - With regard to the analysis of chromosome...Ch. 8 - 4. Describe how colchicine can be used to alter...Ch. 8 - 5. Describe the steps you would take to produce a...Ch. 8 - Prob. 6EQCh. 8 - What are G bands? Discuss how G bands are useful...Ch. 8 - A female fruit fly has one normal X chromosome and...Ch. 8 - Prob. 2QSDCCh. 8 - Besides the ones mentioned in this textbook, look...Ch. 8 - Prob. 4QSDCCh. 8 - 5. Discuss the importance of gene families at the...
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