Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 5, Problem 32RA
Summary Introduction
To review:
The total number of NADH and FADH2 produced during the complete
Introduction:
Beta-oxidation is the breakdown of fatty acids into acetyl-coenzyme A molecules that enter the Krebs cycle or the citric acid cycle and generate a large amount of energy in the form of ATP (adenosine triphosphate) molecules. NADH (nicotinamide adenine dinucleotide hydrogen) and FADH2 (flavin adenine dinucleotide hydrogen) are released, which are the energy carriers.
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Fourteen NADPH molecules are required to produce one molecules of palmitic acid from acetyl CoA. Substantiate this statement by referring to the enzymatic activities involved in reduction steps during fatty acid synthesis and the number of cycles required to produce palmitic acid from acetyl CoA. How many molecules of ATP is required for the synthesis of palmitic acid from cytosolic acetyl-CoA?
How many NADH and FADH2 will be produced when this fatty acid is completely metabolized?
Upon digestion of starch, isomaltose (an isomer of maltose), one of its degradation products, is further hydrolyzed into its monosaccharide components prior to its intestinal absortion and entry into the glycolysis. Calculate the no. of ATP molecules produced from the digestion and complete oxidation of 1 molecule of isomaltose considering the glycerol-3-phosphate shuttle.
Answer the ff.:
a) Total no. of glucose molecules entering glycolysis
b) Total no. of pyruvate molecules produced at the end of glycolysis
c) Total no. of mitochondrial NADH produced after pyruvate is acted upon by the pyruvate dehydrogenase complex
d) Total no. of CO2 released right after the pyruvate dehydrogenase complex reaction
e) Total no. of acetyl-CoA molecules entering the citric acid cycle
f) Total no. of net cytosolic ATP molecules produced right after glycolysis
g) Total no. of all NADH mols. produced after complete oxidation
h)Total no. of all FADH2 mols. produced after complete oxidation
i) Total…
Chapter 5 Solutions
Human Physiology
Ch. 5 - Define the term glycolysis in terms of its initial...Ch. 5 - What are the initial substrates and final products...Ch. 5 - Describe the physiological functions of lactic...Ch. 5 - Compare the fate of pyruvate in aerobic and...Ch. 5 - Draw a simplified citric acid cycle and indicate...Ch. 5 - Explain how NADH and FADH2 contribute to oxidative...Ch. 5 - Explain how ATP is produced in oxidative...Ch. 5 - Describe glycogenesis and glycogenolysis, and...Ch. 5 - Explain the significance of gluconeogenesis and...Ch. 5 - Prob. 6aCP
Ch. 5 - Prob. 6bCPCh. 5 - Describe transamination and deamination and...Ch. 5 - List five blood-borne energy carriers and explain,...Ch. 5 - Prob. 1RACh. 5 - In anaerobic metabolism, the oxidizing agent for...Ch. 5 - When skeletal muscles lack sufficient oxygen,...Ch. 5 - The conversion of lactic acid to pyruvic acid...Ch. 5 - Which of these statements about the oxygen in the...Ch. 5 - In terms of the number of ATP molecules directly...Ch. 5 - Ketone bodies are derived from
Ch. 5 - Prob. 8RACh. 5 - The conversion of glucose 6-phosphate to free...Ch. 5 - The formation of glucose from pyruvic acid derived...Ch. 5 - Which of these organs has an almost absolute...Ch. 5 - When amino acids are used as an energy source,
Ch. 5 - Intermediates formed during fatty acid metabolism...Ch. 5 - State the advantages and disadvantages of the...Ch. 5 - What purpose is served by the formation of lactic...Ch. 5 - Describe the effect of cyanide on oxidative...Ch. 5 - Describe the metabolic pathway by which glucose...Ch. 5 - Prob. 18RACh. 5 - Explain how energy is obtained from the metabolism...Ch. 5 - Prob. 20RACh. 5 - Why is the production of lactic acid termed a...Ch. 5 - Prob. 22RACh. 5 - What three molecules serve as the major substrates...Ch. 5 - A friend, wanting to lose weight, eliminates all...Ch. 5 - Suppose a drug is developed that promotes the...Ch. 5 - For many years, the total number of molecules of...Ch. 5 - People who are starving have very thin arms and...Ch. 5 - Prob. 28RACh. 5 - Prob. 29RACh. 5 - Prob. 30RACh. 5 - Prob. 31RACh. 5 - Prob. 32RACh. 5 - Prob. 33RA
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- Consider oleic acid (18:1∆9): 1. How many NADH will be produced from complete oxidation of this fatty acid? 2. How many FADH2 will be produced from complete oxidation of this fatty acid? 3. Total number of ATP produced from NADH in complete oxidation of oleic acid (exclude transport cost of the fatty acid)? 4. Total number of ATP produced from FADH2 in complete oxidation of oleic acid (exclude transport costs of the fatty acid)? Please provide how you got them.arrow_forwardIndicate whether the following statements are true or false:- a) The pentose phosphate pathway of glucose oxidation can lead to the release of energy. b) NAD + is a coenzyme of transketolase.arrow_forwardEthanol is oxidized in the liver to form acetate, which is then converted to acetyl-CoA. Determine how many molecules of ATP are produced from 1 mol of ethanol. (Note that 2 mol of NADH are produced when ethanol is oxidized to form acetate.)arrow_forward
- Show the first cycle of beta-oxidation of stearic acid. How many ATPs will be generated from the complete oxidation of this fatty acid?arrow_forwardupon digestion of starch maltose, one of its degradation products is further hydrolyzed into its monosaccharide components prior to intestinal absorption and entry into the glycolysis. calculate the number of ATP molecules produced from the digestion and complete oxidation of 1 molecule of maltose considering the glycerol-3-phosphate shuttle. question: 9. what is the total number of net ATP molecules produced after complete oxidation?arrow_forwardFatty acids are stored in adipose tissue, as triacylglycerol (TAG) forms. TAGs are degraded as glycerol and fatty acids where energy is required. Based on that knowledge explain: How these products are used in the adipose, liver, and other tissue? Why glycerol can not be metabolized in adipose tissue?arrow_forward
- Below is a list of steps that occur after an exercising muscle cell begins degrading amino acids for ATP production. For each step, choose (A) if the process occurs in the muscle cell and (B) if the process occurs in the liver. It will be easiest to answer this question if you first put the steps in order, then decide in which organ they occur. ______ Alanine is transaminated with a-ketoglutarate.______ Branched chain amino acids are transaminated with a-ketoglutarate.______ Glutamate is deaminated.______ Glutamate is transaminated with pyruvate.______ Ketoacid skeletons resulting from branch chain amino acids enter the CAC.______ Pyruvate enters gluconeogenesis.______ Urea is formed from the nitrogen removed from the original branched chain amino acid.arrow_forwardIsomaltose (an isomer of maltose), one of the degradation products of starch is further hydrolyzed into its monosaccharide components prior to its intestinal absorption and entry into the glycolysis. Calculate the no. of ATP molecules produced from the digestion and complete oxidation of 1 molecule of isomaltose considering the glycerol-3-phosphate shuttle. Answer the ff.: a) Total no. of glucose molecules entering glycolysis b) Total no. of pyruvate mols. produced at the end of glycolysis c) Total no. of mitochondrial NADH produced after pyruvate is acted upon by pyruvate dehydrogenase complex d) Total no. of CO2 released right after the pyruvate dehydrogenase complex reaction e) Total no. of acetyl CoA mols. entering the Citric Acid Cycle f) Total no. of net cytosolic ATP mols. produced right after glycolysis g) Total no. of all NADH mols. produced after complete oxidation h) Total no. of all FADH2 mols. produced after complete oxidation i) Total no. of all mitochondrial…arrow_forwardAnswer the following: This type of lipid is a complex mixture of esters of long-chain carboxylic acids and long-chain alcohols. The reduced cofactor important in the TCA cycle and used in the last part of respiration. Molecule that attaches to myosin and actin during muscle contraction.arrow_forward
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