Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 48, Problem 1TYK
Summary Introduction

Introduction: The nervous system refers to the network of nerve cells and fibers that transmits nerve impulses between the parts of the human body. Spinal cord and brain are the parts of the central nervous system.

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Explain what happens when an action potential reaches the axon terminus (terminal) by activating the receptors on the postsynaptic membrane.   Explanation addressing the question above When an action potential, or nerve impulse, arrives at the axon terminal, it activates voltage-gated calcium channels in the cell membrane. Which is present at a much higher concentration outside the neuron than inside, rushes into the cell. The Ca​2+​​ allows synaptic vesicles to fuse with the axon terminal membrane, releasing neurotransmitters into the synaptic cleft. The molecules of neurotransmitters diffuse across the synaptic cleft and bind to receptor proteins on the postsynaptic cell. Activation of postsynaptic receptors leads to the opening or closing of ion channels in the cell membrane. This may be depolarizing, making the inside of the cell more positive, or hyperpolarizing making the inside more negative depending on the ions involved. The excitatory and inhibitory postsynaptic potentials…
Which of the following rows correctly completes the following statement about synaptic transmission? The neurotransmitters contained in vesicles enter the synaptic cleft via __A______ to attach to receptor proteins in the postsynaptic membrane. Once the postsynaptic neuron has been stimulated, the neurotransmitters return via ____B_____.   a.  A  B  Exocytosis  Binding b.  A  B  Binding  Exocytosis c.  A  B  Endocytosis  Enzymatic breakdown d.  A  B  Exocytosis  Endocytosis
An undisclosed drug (Drug A) is a drug that can block voltage-gated K+ channels when being introduced into the bloodstream. Explain the effects of Drug A on the action potentials produced by a neuron. If Drug A could be applied selectively to a presynaptic neuron that releases an excitatory neurotransmitter, analyse how would it alter the synaptic effect of the neurotransmitter on the presynaptic cell. Remark: The word count limit (250 words only), no less than 100 words
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