Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 3, Problem 28P
Summary Introduction

To determine:  The genotypes of the parents for each of the resulting progenies.

Introduction. The mutation is the change in the nucleotide sequence of the gene, which results in either the formation of a defective protein or no protein at all. The mutation can also alter the regulation of certain genes leading to their hyperactivity or hypoactivity..

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The pedigree below shows the phenotypes of the ABO blood groups and Rhesus factors [positive (+) and negative (-)] for several members of a family. I (B+ AB- 1 2 3 4 II O- A+ В- B- AB+ A+ 1 2 4 5 6 a. What are the ABO blood group genotypes of individuals I-1 and I-2? b. Which child/ren of individual I-4 can donate blood to him? c. Which individual in the pedigree can donate blood to all the other individuals in the pedigree?
Among dogs, short hair is dominant to long hair and dark coat color is dominant to white (albino) coat color. Assume that these two coat traits are caused by independently segregating gene pairs. For each of the crosses given below, write the most probable genotype (or genotypes if more than one answer is possible) for the parents. It is important that you select a realistic symbol set and define each symbol below. Assume that for cross (d), you were interested in determining whether fur color follows a 3:1 ratio. Set up (but do not complete the calculations) a Chi-square test for these data [fur color in cross (d)].
In dogs, dark coat color is dominant over albino, andshort hair is dominant over long hair. Assume that theseeffects are caused by two independently assorting genes.Seven crosses were done as shown below, in which D andA stand for the dark and albino phenotypes, respectively,and S and L stand for the short-hair and long-hairphenotypes.Number of progenyParental phenotypes D, S D, L A, S A, La. D, S × D, S 88 31 29 12b. D, S × D, L 19 18 0 0c. D, S × A, S 21 0 20 0d. A, S × A, S 0 0 29 9e. D, L × D, L 0 31 0 11f. D, S × D, S 45 16 0 0g. D, S × D, L 31 30 10 10Write the genotypes of the parents in each cross. Use thesymbols C and c for the dark and albino coat-color allelesand the symbols H and h for the short-hair and long-hairalleles, respectively. Assume parents are homozygousunless there is evidence otherwise.
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