Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 3, Problem 14P
Summary Introduction
To determine: The male- and female labeled centromere combinations that are possible in the gametes.
Introduction: The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids. During mitosis, spindle fibers attach to the centromere via the kinetochore.
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In a diploid organism of 2n=10, assume that you can label all the centromeres derived from its female parent and all the centromeres derived from its male parent. When this organism produces gamestes, how many male and female-labeled centromere combinations are possible in the gametes?
A diploid individual is heterozygous for a chromosome rearrangement. The original chromosome and its rearranged homolog have the following segments, where ∙ represents a centromere:
A B ∙ C D E F G
A B ∙ C F E D G
While paired in prophase I, a single crossing-over occurs between segment E and segment D of the paired chromosomes. Describe the unusual crossing-over structure that forms as a result.What gamete types will result from crossing over when meiosis is complete?
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A normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable?
If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?
Chapter 3 Solutions
Introduction to Genetic Analysis
Ch. 3 - Prob. 1PCh. 3 - Prob. 2PCh. 3 - Prob. 4PCh. 3 - Prob. 5PCh. 3 - Prob. 6PCh. 3 - Prob. 7PCh. 3 - Prob. 10PCh. 3 - Prob. 11PCh. 3 - Prob. 12PCh. 3 - Prob. 13P
Ch. 3 - Prob. 14PCh. 3 - Prob. 15PCh. 3 - Prob. 16PCh. 3 - Prob. 17PCh. 3 - Prob. 18PCh. 3 - Prob. 19PCh. 3 - Prob. 20PCh. 3 - Prob. 21PCh. 3 - Prob. 22PCh. 3 - Prob. 23PCh. 3 - Prob. 24PCh. 3 - Prob. 25PCh. 3 - Prob. 26PCh. 3 - Prob. 27PCh. 3 - Prob. 28PCh. 3 - Prob. 29PCh. 3 - Prob. 30PCh. 3 - Prob. 31PCh. 3 - Prob. 31.1PCh. 3 - Prob. 31.2PCh. 3 - Prob. 31.3PCh. 3 - Prob. 31.4PCh. 3 - Prob. 31.5PCh. 3 - Prob. 31.6PCh. 3 - Prob. 31.7PCh. 3 - Prob. 31.8PCh. 3 - Prob. 31.9PCh. 3 - Prob. 31.10PCh. 3 - Prob. 31.11PCh. 3 - Prob. 31.12PCh. 3 - Prob. 31.13PCh. 3 - Prob. 31.14PCh. 3 - Prob. 31.15PCh. 3 - Prob. 32PCh. 3 - Prob. 33PCh. 3 - Prob. 34PCh. 3 - Prob. 35PCh. 3 - Prob. 36PCh. 3 - Prob. 37PCh. 3 - Prob. 38PCh. 3 - Prob. 39PCh. 3 - Prob. 40PCh. 3 - Prob. 41PCh. 3 - Prob. 42PCh. 3 - Prob. 43PCh. 3 - Prob. 44PCh. 3 - Prob. 45PCh. 3 - Prob. 46PCh. 3 - Prob. 48PCh. 3 - Prob. 49PCh. 3 - Prob. 50PCh. 3 - Prob. 51PCh. 3 - Prob. 52PCh. 3 - Prob. 53PCh. 3 - Prob. 54PCh. 3 - Prob. 57P
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- A 2n=4 plant is heterozygous at two genes, one controlling plant height (T = tall, t= short) and one controlling disease resistance (D = resistant, d = susceptible). The plant height gene is located on one chromosome, and the disease resistance gene is located on the other chromosome. In the cells below, draw to two possible arrangements of the chromosomes at metaphse I of meiosis. Hint: look at Figure 2.17 in your textbook for an example of how chromosomes can be arranged at metaphase I. Be sure to label the alleles present at the genes on the two chromosomes in each drawing. 00arrow_forwardA diploid organism produces four gametes from one parent cell through the process of meiosis. Two gametes are found to have 7 chromosomes and two gametes are found to have 5 chromosomes. A) Is this the expected number of chromosomes that would be found in each gamete following a normal cycle of meiosis? If yes, explain why. If no, explain why not and describe how the gamete situation described above occurred. B) Determine the number of homologous chromosome pairs that the original parent cell contained, before meiosis began. Explain how you determined this value.arrow_forwardAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Draw the pairing arrangement of these chromosomes in prophase I of meiosis.arrow_forward
- What is the probability that, in an organism with a haploid number of 10, a sperm will be formed that contains all 10 chromosomes whose centromeres were derived from maternal homologs?arrow_forwardA specific human individual with a male sex has the same sex chromosome complement as a metafemale Drosophila fly. Both individuals have a diploid set of autosomes.i) What is the sex chromosome complement of these two individuals? ii) If these individuals were produced from a fertilization event involving an abnormal egg and abnormal sperm cell, provide the genetic make-up of the two gametes? Clearly indicate the male and female gametes.arrow_forwardConsider the following two meiocytes in metaphase I, with crossover positions as indicated for cell A. Solid black lines indicate spindle microtubules. Assume blue chromosomes represents paternal chromosomes and green maternal chromosomes. i) How many chromosomes and chromatids were present in cell A during the G1 phase? Please clearly specify chromosomes and chromatids in your answer. ii) For cell A, list all the gametes that will be produced from this cell. Give the alleles of each gamete contained within a set of brackets. You may ignore independent assortment.iii) For cell B, list all the gametes that will be produced from this cell given crossing over. Give the alleles of each gamete contained within a set of brackets. You may assume that no crossing over would take place.arrow_forward
- If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the F1 be expected to produce? Derive the expected F2 genotypic and phenotypicarrow_forwardA reciprocal translocation between chromosome 1 and 2 in Drosophila resulted in AB//CPQR and MN//ODEF. Double stroke indicates centromere location. (i) Diagram the alignment of these chromosomes during meiosis. (ii) What will be the gametes produced by alternate segregation, adjacent 1 segregation and adjacent 2 segregation?arrow_forwardA diploid (2n) trihybrid individual with the genotype EeFfGg can make eight genetically different gametes. Loci E/e and F/f are on chromosome 1 and locus G/g is on chromosome 2. Explain how a gamete containing the alleles e, f and g may be produced by meiosis. Refer specifically to meiotic events occurring during Prophase I, Metaphase I, Anaphase I and Anaphase II. (NB: remember to refer to the organism above).arrow_forward
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