Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 3, Problem 21P
Summary Introduction

To determine: The proportion of his children will have the same karyotype that he has.

Introduction: Karyotyping is the process by which photographs of chromosomes are taken to determine the chromosome complement of an individual, including the number of chromosomes and any abnormalities.

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Suppose you discover two interesting rare cytological abnormalities in the karyotype of a human male. (Akaryotype is the total visible chromosome complement.) There is an extra piece (satellite) on one of the chromosomes of pair 4, and there is an abnormal pattern of staining on one of the chromosomes of pair 7. With the assumption that all the gametes of this male are equally viable, what proportion of his children will have the same karyotype that he has?
A couple comes into a fertility clinic. A chromosome preparation is made for each and the male is found to have an aberrant karyotype. He is heterozygous for two sets of reciprocal translocations involving four different chromosome pairs. What proportion of his gametes are expected to be functional and viable?
You are an allele on a single uncondensed chromosome in a Yellow fever-carrying mosquito (Aedes aegypti) diploid cell (2n = 6). Demonstrate in as much detail as possible: (1) how you will get to each genetically identical diploid cell of the multicellular offspring. (2) how you will get to the next generation of sexually reproduced progeny.
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