For the synthesis of metenkephalin, the mRNA sequence has to be synthesized. Concept Introduction: Codon: A sequence of three ribonucleotides in the mRNA chain that codes for a specific amino acid; also a three- nucleotide sequence that is a stop codon and stops translation. Genetic code: The sequence of nucleotides, coded in triplets (codons) in mRNA that determines the sequence of amino acids in protein synthesis. Illustrated relationships are: DNA informational strand : 5’ ATG CCA GTA GGC CAC TTG TCA 3’ DNA Template strand : 3’ TAC GGT CAT CCG GTG AAC AGT 5’ m RNA: 5’ AUG CCA GUA GGC CAC UUG UCA 3’ protein: Met Pro Val Gly His Leu Ser Notice: 5’ end of the mRNA strand codes for the N-terminal amino acid, whereas the 3’ end of the mRNA strand codes for the C-terminal amino acid. Proteins are always written N-terminal to C-terminal, reading left to right.

Question

Want to see the full answer?

Answer 1

Question

Chapter 26, Problem 26.66AP

Interpretation Introduction

Interpretation:

For the synthesis of metenkephalin, the mRNA sequence has to be synthesized.

Concept Introduction:

Codon: A sequence of three ribonucleotides in the mRNA chain that codes for a specific amino acid; also a three-nucleotide sequence that is a stop codon and stops translation.

Genetic code: The sequence of nucleotides, coded in triplets (codons) in mRNA that determines the sequence of amino acids in protein synthesis.

Illustrated relationships are:

**DNA informational strand: 5’ ATG CCA   GTA GGC CAC   TTG   TCA 3’

DNA Template strand:         3’ TAC GGT   CAT CCG GTG   AAC   AGT 5’

mRNA:                                  5’ AUG CCA GUA GGC CAC UUG   UCA 3’

protein:**                                      Met    Pro     Val    Gly     His    Leu      Ser

Notice: 5’ end of the mRNA strand codes for the N-terminal amino acid, whereas the 3’ end of the mRNA strand codes for the C-terminal amino acid. Proteins are always written N-terminal to C-terminal, reading left to right.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

The genetic disorder sickle-cell anemia occurs when the amino acid valine takes the place of glutamate during translation of a hemoglobin chain. Using the table of codons below, determine the mutation in DNA that produces this disorder. 1st position ✓ U C A G Select one: U C serine phenylalanine phenylalanine serine leucine serine leucine serine leucine leucine leucine leucine isoleucine isoleucine isoleucine methionine Table of mRNA Codons 2nd position valine valine valine valine proline proline proline proline alanine alaninc alanine alanine A tyrosine tyrosine a. CUC changes to C AG b. GAA changes to GUU c. CTT changes to CAT d. C A G changes to CTC stop stop threonine asparagine threonine asparagine threonine threonine histidine histidine arginine arginine glutamine arginine glutamine arginine lysine lysine G cysteine cysteine stop tryptophan aspartate aspartate glutamate glutamate serine serine arginine arginine glycine glycine glycine glycine 3rd position DCMO U С A G U C A G…

When the amino acid sequences of insulin isolated from different organisms were determined, differences were noted. For example, alanine was substituted for threonine, serine for glycine, and valine for isoleucine at corresponding positions in the protein. List the single-base changes that could occur in codons of the genetic code to produce these amino acid changes.

Choose a pentapeptied composed of five different amino acids. List the five amino acids. Present the messenger RNA codons for the amino acids and the sequence of the nucleotids on the DNA that was originally coded for the pentapeptide.