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Concept Introduction:
Replication of DNA: The process by which copies of DNA are made when a cell divides. During cell division, the DNA in the nucleus undergoes replication. Initially, partial unwinding of double strand is achieved by the use of an enzyme called helicases; unwinding occurs in many specific locations known as origins of replication. At the site of replication forks, DNA polymerases move onto the leading separated strand, one by one specific base of triphosphate
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
- Why does DNA replication produce two daughter strands that are identical to each other and to the parent DNA?arrow_forwardWhat is the difference between the leading strand and the lagging strand in DNA replication? There are different DNA polymerases involved in elongation of the leading strand and the lagging strand. The leading strand is synthesized continuously in the 5' → 3' direction, while the lagging strand is synthesized discontinuously in the 5' → 3' direction. The leading strand requires an RNA primer, whereas the lagging strand does not. The leading strand is synthesized in the 3' → 5' direction in a discontinuous fashion, while the lagging strand is synthesized in the 5' → 3' direction in a continuous fashion.arrow_forwardIf the sequence of one single strand of DNA is C-A-A-G-T-A-G-G-C-T, what is the sequence of the complementary strand? Describe the origin of each strand of the new double helices created after DNA replication. Why is DNA replication important to the growth and development of a multicellular organism? Place the following terms in the correct order from smallest to largest: Nucleosome, supercoils, coils, chromosome, DNA double helixarrow_forward
- Why is DNA replication is considered a semi-discontinuous process? Explain in detail.arrow_forwardWhat is bidirectional replication?arrow_forwardWhy is the replication of DNA referred to as a semiconservative process? What is the experimental evidence for the semiconservative nature of the process? What experimental results would you expect if replication of DNA were a conservative process?arrow_forward
- Why is replication important?arrow_forwardWhy must replication of DNA proceed in two opposite directions? And what differs about how DNA replication occurs in each direction?arrow_forwardAs a result of DNA replication two DNA molecules come into existence. Why is it not correct to assert that two “new” DNA molecules are created? What is the name given to the process concerning that fact?arrow_forward
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning