Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 20, Problem 5RQ
How do the two limbs of the loop of Henle differ in their permeability to water? What makes this difference in permeability possible?
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One type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle.
A) What does it mean to inhibit the transport of sodium ions in the loop of Henle?
B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.
Describe the characteristics of the two limbs of the loop of Henle with regard to their transport of Na1, Cl2, and water.
Identify the mechanism of transport used in this location across the simple cuboidal cell of the proximal convoluted tubule
Choose from the following:
(A) facilitated diffusion
(B) simple diffusion
(C) active transport
(D) secondary active transport
Chapter 20 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 20.2 - Does the apical membrane of a collecting duct cell...Ch. 20.2 - Prob. 2CCCh. 20.2 - A scientist monitoring the activity of...Ch. 20.2 - If vasopressin increases water reabsorption by the...Ch. 20.2 - Experiments suggest that there are peripheral...Ch. 20.2 - Prob. 6CCCh. 20.2 - Prob. 7CCCh. 20.3 - In Figure 20.9b, what forces cause Na+ and K+ to...Ch. 20.3 - Prob. 9CCCh. 20.3 - Laboratory values for ions may be reported as...
Ch. 20.3 - A man comes to the doctor with high blood...Ch. 20.3 - Map the pathways through which elevated renin...Ch. 20.3 - Why is it more efficient to put ACE in the...Ch. 20.5 - Incorporate the thirst reflex into Figure 20.8.Ch. 20.6 - Map the pathway that begins with renal artery...Ch. 20.7 - CO2+H2OH++HCO3(6) In equation 6, the amount of...Ch. 20.7 - Why is ATP required for H+ secretion by the H+-K+...Ch. 20.7 - In hypokalemia, the intercalated cells of the...Ch. 20 - What is an electrolyte? Name five electrolytes...Ch. 20 - Prob. 2RQCh. 20 - Prob. 3RQCh. 20 - List the receptors that regulate osmolarity, blood...Ch. 20 - How do the two limbs of the loop of Henle differ...Ch. 20 - Prob. 6RQCh. 20 - Prob. 7RQCh. 20 - Prob. 8RQCh. 20 - Write out the words for the following...Ch. 20 - Prob. 10RQCh. 20 - Prob. 11RQCh. 20 - Prob. 12RQCh. 20 - Prob. 13RQCh. 20 - Prob. 14RQCh. 20 - Prob. 15RQCh. 20 - When ventilation increases, what happens to...Ch. 20 - Prob. 17RQCh. 20 - Figures 20.15 and 20.18a show the respiratory and...Ch. 20 - Explain how the loop of Henle and vasa recta work...Ch. 20 - Prob. 20RQCh. 20 - Prob. 21RQCh. 20 - Name the four main compensatory mechanisms for...Ch. 20 - Prob. 23RQCh. 20 - Compare and contrast the terms in each set: a....Ch. 20 - Prob. 25RQCh. 20 - Prob. 26RQCh. 20 - Prob. 27RQCh. 20 - Hannah, a 31-year-old woman, decided to have...Ch. 20 - Prob. 29RQCh. 20 - Prob. 30RQCh. 20 - The Henderson-Hasselbalch equation is a...Ch. 20 - Hyperglycemia in a diabetic patient leads to...Ch. 20 - Osmotic diuresis refers to the loss of additional...
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- a. A person ingests an ion-channel inhibitor, such that the ion channels present in the Loop of Henle are only able to pump at half their normal rate? b. What would this person notice about changes to their physiological filtration? (Answer a and b)arrow_forwardMention the difference between overhydration, dehydration, and imbalane of osmotic fluid. Atleast 2 difference.arrow_forwardWhat is Osmotic pressure ? Why it is used ?arrow_forward
- What effect does digitalis have on the Na and K gradients? Why?arrow_forwardWhen the kidneys filter plasma, the filtered glucose is reabsorbed from the renal tubules and is not passed in the urine. However, glucose can appear in the urine when the blood sugar is exceptionally high. Given that glucose is reabsorbed by carrier-mediated transport, what functional aspect of carrier-mediated transport does the appearance of glucose in urine demonstrate? Explain.arrow_forwardWhat two mechanisms are triggered by an increase in theosmolality of the extracellular fluid?arrow_forward
- Explain what are countercurrent exchangers? Explain how are they used in the conservation of temperature. How is it used to extract oxygen in gills? How is it used to eliminate waste in the Malpighian tubules? How is a counter current multiplier used to concentrate urine in the kidney?arrow_forward1. There is a medical condition called Syndrome of Inappropriate Anti-Diuretic Hormone (SIADH) secretion, which can occur as a result of head trauma. Patients with this condition retain water and present with a volume imbalance. A) Name the type of volume imbalance and accompanying direction of changes in ICF and ECF volumes and osmolality. B) Calculate the changes in osmolality and volumes of extracellular and intracellular fluid compartments if 3 liters of water are retained by a patient with SIADH. You can assume that the patient’s initial volumes were ECF=14 L, ICF=28 L. And his initial body osmolality = 290 mOsM. Remember that the total solute in the ICF compartment is kept in place by the cell membrane barrier.arrow_forward6) Consider the mechanism of net NaCl secretion across an epithelium shown below: b) What is the driving force for Na+ transport through the paracellular pathway? c) What is the significance of K+ channels located on the basolateral membrane?arrow_forward
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