Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 20, Problem 26RQ
Summary Introduction
To determine: The renal function of the vasopressin receptor antagonists and the disease in which these drugs can be used.
Introduction: Human beings have a pair of kidneys. The essential function of kidneys is to eliminate toxic substances and reabsorb water, sodium, and other nutrients from the body.
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Nearly all renal diseases result in hypertension. In fact, some clinicians have a 'rule' that states "unexplained hypertension is always a result of a problem with the kidneys until proven otherwise". Briefly explain why hypertension occurs in renal disease.
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Chapter 20 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 20.2 - Does the apical membrane of a collecting duct cell...Ch. 20.2 - Prob. 2CCCh. 20.2 - A scientist monitoring the activity of...Ch. 20.2 - If vasopressin increases water reabsorption by the...Ch. 20.2 - Experiments suggest that there are peripheral...Ch. 20.2 - Prob. 6CCCh. 20.2 - Prob. 7CCCh. 20.3 - In Figure 20.9b, what forces cause Na+ and K+ to...Ch. 20.3 - Prob. 9CCCh. 20.3 - Laboratory values for ions may be reported as...
Ch. 20.3 - A man comes to the doctor with high blood...Ch. 20.3 - Map the pathways through which elevated renin...Ch. 20.3 - Why is it more efficient to put ACE in the...Ch. 20.5 - Incorporate the thirst reflex into Figure 20.8.Ch. 20.6 - Map the pathway that begins with renal artery...Ch. 20.7 - CO2+H2OH++HCO3(6) In equation 6, the amount of...Ch. 20.7 - Why is ATP required for H+ secretion by the H+-K+...Ch. 20.7 - In hypokalemia, the intercalated cells of the...Ch. 20 - What is an electrolyte? Name five electrolytes...Ch. 20 - Prob. 2RQCh. 20 - Prob. 3RQCh. 20 - List the receptors that regulate osmolarity, blood...Ch. 20 - How do the two limbs of the loop of Henle differ...Ch. 20 - Prob. 6RQCh. 20 - Prob. 7RQCh. 20 - Prob. 8RQCh. 20 - Write out the words for the following...Ch. 20 - Prob. 10RQCh. 20 - Prob. 11RQCh. 20 - Prob. 12RQCh. 20 - Prob. 13RQCh. 20 - Prob. 14RQCh. 20 - Prob. 15RQCh. 20 - When ventilation increases, what happens to...Ch. 20 - Prob. 17RQCh. 20 - Figures 20.15 and 20.18a show the respiratory and...Ch. 20 - Explain how the loop of Henle and vasa recta work...Ch. 20 - Prob. 20RQCh. 20 - Prob. 21RQCh. 20 - Name the four main compensatory mechanisms for...Ch. 20 - Prob. 23RQCh. 20 - Compare and contrast the terms in each set: a....Ch. 20 - Prob. 25RQCh. 20 - Prob. 26RQCh. 20 - Prob. 27RQCh. 20 - Hannah, a 31-year-old woman, decided to have...Ch. 20 - Prob. 29RQCh. 20 - Prob. 30RQCh. 20 - The Henderson-Hasselbalch equation is a...Ch. 20 - Hyperglycemia in a diabetic patient leads to...Ch. 20 - Osmotic diuresis refers to the loss of additional...
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- Which of the following does not contribute to the process of filtration? (a) active transport by epithelial cells lining renal tubules (b) large surface area for filtration (c) low permeability of glomerular capillaries (d) high hydrostatic blood pressure in glomerular capillaries (e) podocytesarrow_forwardFatty tissue holds the kidneys in place. Extremely rapid weight loss may cause this tissue to shrink so that the kidneys slip from their normal position. On rare occasions, the slippage can put a kink in one or both ureters and block urine flow. Suggest what might then happen to the kidneys.arrow_forwardWhich of the following does not contribute to the high salt concentration in the interstitial fluid of the kidney medulla? (a) active transport of sodium from the upper part of the ascending limb (b) diffusion of salt from the ascending limb of the loop of Henle (c) reabsorption of salt from various regions of Bowmans capsule (d) counterflow of fluid through the two limbs of the loop of Henle (e) diffusion of urea out of the collecting ductarrow_forward
- The afferent arteriole delivers blood to the (a) renal artery (b) efferent arteriole (c) renal vein (d) capillaries of the glomerulus (e) peritubular capillariesarrow_forwardA urinalysis reveals that the patients urine contains glucose, hemoglobin, and white blood cells (pus). Are any of these substances abnormal in urine? Explain.arrow_forwardwhich of the following is NOT describing the homeostatic function of renal system? Select one: a. Not effective in regulation of acid-base balance b. Very effective in regulation of arterial blood pressure c. Secretion of insulin d. No role in gluconeogenesis e. Regulation of blood glucosearrow_forward
- An investigator is studying renal physiology in patients with type 1 diabetes mellitus. When a substance that inhibits glucose reabsorption is given, which of the following best describes the clearance of glucose?a. Decreases and approaches the clearance of p-aminohippurateb. Decreases and approaches the clearance of inulinC. Increases and approaches the clearance of p-aminohippurated. Increases and approaches the clearance of inuline. Increases and approaches the clearance of sodiumarrow_forwardA patient has essential hypertension, and with a healthy lifestyle and medication, he is able to maintain normal blood pressure on a single antihypertensive medication. The medication he takes is called an angiotensin converting enzyme inhibitor, or ACE inhibitor, which blocks the activation of angiotensin II. Describe at least two mechanisms by which angiotensin II targets the kidneys to increase extracellular fluid volume and, therefore, increase blood pressure.arrow_forwardWhich of the following is a component of the renal response to metabolicacidosis?a. reabsorption of H1b. secretion of HCO3 2 into the tubular lumenc. secretion of ammonium into the tubular lumend. secretion of glutamine into the interstitial fluide. carbonic anhydrase-mediated production of HPO4 22arrow_forward
- Renin is an important proteolytic enzyme produced by the kidney, involved in the control of salt/water balance in the body. Explain the source of renin, how it is secreted and how it acts to ultimately influence plasma volume. A separate hormonal system exists for directly controlling kidney water reabsorption. Explain how this hormone is released and how it exerts its renal effects.arrow_forwardWhich of the following is TRUE about glucose reabsorption in the kidney? a.If an individual does not have diabetes mellitus, 100% of filtered glucose is reabsorbed at the proximal convoluted tubule. b.If an individual has diabetes mellitus, filtered glucose will be present in all the renal tubule. c.Glucose reabsorption along the proximal convoluted tubule uses the sodium glucose secondary active transporter and it is independent of insulin. d.All of the above e.None of the above asaparrow_forward
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