Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 18.4, Problem 2COMQ
Summary Introduction
Introduction:
HIV (Human Immunodeficiency Virus) is a virus that mainly impacts the immunity of an individual and increases the risk of other diseases. It leads to AIDS (Acquired ImmunoDeficiency Syndrome) with time. It is a lifelong infection.
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People with the CCR5Δ32 mutation of a T-cell surface protein can be exposed to some strains of HIV-1 without becoming sick. What step of the virus life cycle is likely to be inhibited with this mutation? a. Release b. Reverse transcription c. Uncoating d. Attachment
69) in the first round of translation in Sheeppoxviruses the products are
a. the proteins go back to the nucleus
b. are composed of structural and non-structural proteins.
c. this round of translation happened before the DNA genome replication
d. among these products are the cellular RNA polymerase.
If the HIV did not have a reverse transcriptase enzyme, then which of the following would apply?
Select one:
a. The virus can make use of the reverse transcriptase enzyme from the host cell to convert its RNA into
DNA
b. Viral particles will be produced without reverse transcriptase enzyme since the original HIV is an
RNA virus and needs to assemble RNA ant coat proteins together
c. The virus will manufacture its proteins from its RNA using translation and ribosomes from host cell
d. Provirus will not be formed and assembly of viral particles will never occur
e. The virus will not be able to recognise the host cell and therefore entry into the cell is blocked
Chapter 18 Solutions
Genetics: Analysis and Principles
Ch. 18.1 - 1. What is a common feature found in all viruses?...Ch. 18.1 - 2. Viral genomes can be
a. DNA or RNA.
b....Ch. 18.2 - Prob. 1COMQCh. 18.2 - Prob. 2COMQCh. 18.3 - A mutation in phage results in 10-fold greater...Ch. 18.3 - 2. The cl gene that encodes the λ repressor has...Ch. 18.4 - A viral protein that is needed to make HIV DNA is...Ch. 18.4 - Prob. 2COMQCh. 18.4 - After HIV components are made, what is the correct...Ch. 18 - 1. Discuss why viruses are considered nonliving.
Ch. 18 - What structural features are common to all...Ch. 18 - 3. What are the similarities and differences among...Ch. 18 - Prob. 4CONQCh. 18 - Prob. 5CONQCh. 18 - Prob. 6CONQCh. 18 - Prob. 7CONQCh. 18 - Prob. 8CONQCh. 18 - Prob. 9CONQCh. 18 - Prob. 10CONQCh. 18 - 11. What is a prophage, a provirus, and an...Ch. 18 - Prob. 12CONQCh. 18 - Prob. 13CONQCh. 18 - 14. With regard to promoting the lytic or...Ch. 18 - 15. How do therepressor and the cro protein affect...Ch. 18 - Prob. 16CONQCh. 18 - Figure 18.11 shows a genetic switch that controls...Ch. 18 - Prob. 18CONQCh. 18 - Prob. 19CONQCh. 18 - Explain the role of RNase H (a component of...Ch. 18 - Prob. 21CONQCh. 18 - Prob. 22CONQCh. 18 - Prob. 23CONQCh. 18 - 24. Compare and contrast the roles of fully...Ch. 18 - 25. Describe the role of the Gag polyprotein...Ch. 18 - Prob. 26CONQCh. 18 - Prob. 27CONQCh. 18 - 1. Discuss how researchers determined that TMV is...Ch. 18 - Prob. 2EQCh. 18 - What is a reconstituted virus?Ch. 18 - Following the infection of healthy tobacco leaves...Ch. 18 - Prob. 5EQCh. 18 - Prob. 6EQCh. 18 - A researcher identified a mutation in PR of phage ...Ch. 18 - Experimentally, when an E. coli bacterium already...Ch. 18 - 9. A bacterium is exposed to a drug that inhibits...Ch. 18 - This question combines your knowledge of bacterial...Ch. 18 - Prob. 1QSDCCh. 18 - 2. Certain environmental conditions such as...Ch. 18 - 3. Browse the Internet to determine the drugs that...
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- Which Class I element has likely experienced the greatest accumulation of mutations compared to its retrovirus ancestor, as its DNA sequence is the most divergent? A. LINES B. transposons C. Ac/Ds elements D. SINES E. LTR retrotransposonsarrow_forward91) The NDV virus a. The mesogenic ND is less virulent than lentogenic than NDV b. The antigenomic copy is the template for both making genome and making subgenus c. The RNA polymerase is only made in the first round of translation d. The Fusion protein is the virulent proteinarrow_forwardThe HIV virus produces copies of its genome through: A. DNA replication B. Reverse transcription followed by integration then normal transcription C. RNA replication from an RNA template D. differential splicingarrow_forward
- How does a retrovirus prepare its genetic material for incorporation into the host cell genome? a. Host enzymes incorporate viral RNA directly into the genome. b. Host enzymes covert viral RNA to double-stranded viral DNA. c. Viral reverse transcriptase uses viral RNA to make double-stranded viral RNA. d. Viral reverse transcriptase uses viral RNA to make double-stranded viral DNA. e. Viral reverse transcriptase uses viral single-stranded DNA to make double-stranded viral DNA.arrow_forwardWhy are vaccines and/or passive immunization the method of choice in the treatment or prevention of viral infections? A. There are no known inhibitors to reverse transcription B. Viruses are non-living and do not have their own genetic mechanisms to reproduce by themselves hence host cells must rely on targeting the virus or their products. C. Antibodies prevent replication of viral genome D. Antibodies prevent transcription and translation of viral genomes E. All of thesearrow_forwardHow is it verified that the Lc chain formed is functional? a. translation is carried out b. the complete receptor (BCR) is formed c. join the Hc chain d. binds to an antigenarrow_forward
- Leaky scanning allows multiple viral proteins to be synthesized from a single mRNA. A. True B. Falsearrow_forwardA man was brought to the hospital showing "pneumonia"-like symptoms. They took the viral load and determined this to be the new RNA retrovirus infecting lung cells. Since antibodies were unavailable, doctors decided to treat him with drugs. Which of the following would most benefit the patient? A. Drug A is an inhibitor of the binding of 4OS with 60S ribosome of the lung cells. B. Drug B is a structural analogue of the viral peptide that binds to the receptor of the host cell enabling viral entry into the cell. C. Drug C is a polar molecule that inhibits the lytic enzymes activated upon viral infection. D. Drug D is an inducer of a proteolytic enzyme. E. Drug E is a steroid that binds at the regulatory site of a gene causing the synthesis of a repressor that binds at the gene site for the receptor.arrow_forwardWhich type of RNA comprises over 80% of total cellular RNA? A. ribosomal RNA B. Messenger RNA C. Transfer RNAarrow_forward
- A retrotransposon does NOT contain genes for which polyprotein? a. gag b. pol c. It contains genes for all of these polyproteins d. envarrow_forwardA virus is isolated, and individual virions appear spherical. What type of virus is this? A. Bacteriophage B. Helical C. Icosahedral D. Lysogenicarrow_forwardWhich nucleic-acid based technique will detect norovirus? A. Fluorescent In Situ Hybridization (FISH) probes B. PCR with primers specific for the genome of this virus C. Terminal Restriction Fragment Length Polymorphism (T-RFLP) D. reverse transcription PCR with specific primers A patient's blood sample tests positive for the antigen to Vibrio cholerae. Which of the following interpretations is correct? A. This person has cholera. B. This person was exposed to any species of Vibrio. C. This person was exposed to V. cholerae recently. D. This person had cholera at some point in their lifetime.arrow_forward
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